13F

Investor

SILVERARC CAPITAL MANAGEMENT, LLC

CIK 0001816307 · filed 2026-05-14 · SEC filing

13F book

$979.8M

Positions

67

21 new · 18 sold

Largest name

5.9%

Kalvista Pharmaceuticals Inc

Est. mark

$75.8M

Price effect on 46 names still held. Flow $81.7M.
NameTickerSharesValueWeightEst. markChange
Kalvista Pharmaceuticals Inc2.88M$57.9M5.9%$9.66MAdded$18.7M
Dianthus Therapeutics Inc654.7K$54.9M5.6%$28MCut$24M
Cogent Biosciences, Inc.COGT1.31M$50.6M5.2%$3.7MAdded$6.35M
Celcuity Inc.CELC357.9K$40.9M4.2%$5.15MCut$3.44M
Immunome Inc.IMNM1.85M$40.5M4.1%$439.2KAdded$16.3M
Kodiak Sciences Inc.KOD991.9K$37.8M3.9%$10.1MCut$9.21M
Nuvalent Inc354.9K$36.4M3.7%$579.3KAdded$5.03M
Abivax Sa302.5K$33.7M3.4%−$7.11MCut−$23.2M
Monte Rosa Therapeutics, Inc.GLUE2M$32.9M3.4%$792.4KAdded$16.8M
Erasca, Inc.ERAS1.85M$30M3.1%$16.4MAdded$25.1M
Ascendis Pharma A/SASND124.7K$28.5M2.9%$762.5KAdded$18M
UroGen Pharma Ltd.URGN1.5M$27M2.8%−$8.18MCut−$13.7M
Rhythm Pharmaceuticals, Inc.RYTM306K$26.6M2.7%−$2.73MAdded$12.1M
Praxis Precision Medicines I71.6K$23.1M2.4%$1.96MCut−$1.25M
Zenas BioPharma, Inc.ZBIO1.14M$22.2M2.3%New
Syndax Pharmaceuticals IncSNDX889K$20.8M2.1%$1.51MAdded$7.26M
Centessa Pharmaceuticals Plc466.3K$18.5M1.9%$6.74MAdded$7.06M
Scholar Rock Hldg Corp339.6K$16.7M1.7%New
Alkermes plc.ALKS460.3K$16.3M1.7%New
Oric Pharmaceuticals, Inc.ORIC1.1M$13.9M1.4%$4.94MCut$4.8M
Disc Medicine, Inc.IRON196K$12.5M1.3%New
Helix Acquisition Corp. IIIHLXC1.21M$12.3M1.3%New
Xenon Pharmaceuticals Inc.XENE197.8K$11.5M1.2%New
CG Oncology, Inc.CGON166.3K$11.3M1.1%$4.35MCut−$3.74M
Immunovant, Inc.IMVT414.2K$10.3M1.1%New
Spyre Therapeutics, Inc.SYRE186.6K$9.41M1.0%$3.3MCut$3.26M
Biogen Inc.BIIB51K$9.34M1.0%$374.1KCut−$3.93M
Guardant Health, Inc.GH98.5K$9.1M0.9%−$898KAdded−$288.4K
Vaxcyte, Inc.PCVX145K$8.42M0.9%$1.74MCut$1.56M
Savara IncSVRA1.43M$7.81M0.8%New
Benitec Biopharma Inc.BNTC717.7K$7.64M0.8%−$2.02MCut−$2.21M
Oruka Therapeutics, Inc.ORKA150.9K$7.4M0.8%New
Compugen LtdCGEN3.32M$7.06M0.7%$1.99MCut$1.74M
Trevi Therapeutics, Inc.TRVI511.1K$6.1M0.6%−$301.6KCut−$678.6K
Insmed IncINSM35.9K$5.86M0.6%−$377.1KCut−$6.54M
Veracyte, Inc.VCYT179.7K$5.79M0.6%−$1.78MCut−$9.27M
Cerus CorpCERS3.18M$5.78M0.6%−$675.5KAdded−$16.3K
Celldex Therapeutics Inc New178.4K$5.66M0.6%$813.4KCut$468.6K
C4 Therapeutics, Inc.CCCC1.91M$5.03M0.5%$1.38MCut$1.22M
Cytokinetics IncCYTK71.2K$4.69M0.5%New
Climb Bio, Inc.CLYM684.9K$4.69M0.5%New
Compass Therapeutics, Inc.CMPX859K$4.54M0.5%−$68.7KCut−$1.1M
Surrozen Inc144.3K$4.2M0.4%$942KCut$646.6K
Contineum Therapeutics, Inc.CTNM301.7K$3.94M0.4%$491.8KCut$425.4K
Zura Bio LtdZURA560.7K$3.34M0.3%New
Fulcrum Therapeutics, Inc.FULC419.9K$3.22M0.3%−$1.44MAdded−$1.24M
Abeona Therapeutics Inc.ABEO648.9K$2.91M0.3%−$495.9KAdded−$400.9K
Camp4 Therapeutics CorpCAMP653.6K$2.88M0.3%New
Annexon, Inc.ANNX496.5K$2.75M0.3%New
Elutia Inc.ELUT2.5M$2.62M0.3%$892.5KCut$717.1K
Crescent Biopharma, Inc.CBIO130.5K$2.4M0.2%New
Monopar TherapeuticsMNPR43.5K$2.38M0.2%New
Ovid Therapeutics Inc.OVID1M$2.22M0.2%New
NextCure, Inc.NXTC176.1K$1.88M0.2%−$618KHeld
Compass Pathways PlcCMPS300K$1.66M0.2%New
Neumora Therapeutics, Inc.NMRA818.2K$1.6M0.2%New
Sionna Therapeutics, Inc.SION39.4K$1.58M0.2%−$41.4KCut−$125.4K
TELA Bio, Inc.TELA2.26M$1.4M0.1%−$1.27MCut−$1.72M
Edgewise Therapeutics, Inc.EWTX42.6K$1.34M0.1%$281.1KAdded$298.9K
Replimune Group, Inc.REPL171.9K$1.32M0.1%New
Generate Biomedicines, Inc.GENB100K$1.25M0.1%New
Radiopharm Theranostics Ltd187.4K$805.8K0.1%−$172.4KHeld
Fractyl Health, Inc.GUTS1.7M$779K0.1%−$2.96MCut−$20.9M
iBio, Inc.IBIO226K$429.4K0.0%−$3.18KAdded$224.8K
Adagio Med Hldgs Inc252K$289.8K0.0%$27.7KCut−$246.2K
Aardvark Therapeutics, Inc.AARD33.7K$127K0.0%−$315.1KCut−$3.86M
Rocket Pharmaceuticals Inc104.8K$2.16K0.0%−$388Held

Positions as of Q1 2026. 13F filings arrive up to 45 days after quarter-end and omit shorts. Values are quarter-end marks, as filed. Estimated mark is the price effect on shares still held — not realized P&L or investment advice.