| Siren, L.L.C. | 8.5M | $16.6M | $1.01M | Added$5.31M |
| SOFTBANK GROUP CORP. | 6.09M | $11.9M | $974.4K | Added$366.9K |
| PERCEPTIVE ADVISORS LLC | 5.1M | $9.95M | — | New |
| MIC Capital Management UK LLP | 4.46M | $8.7M | $713.7K | Added$713.7K |
| VANGUARD CAPITAL MANAGEMENT LLC | 3.89M | $7.59M | — | Held |
| Fidelity | 3.5M | $6.82M | $559.7K | Added$560.5K |
| WELLCOME TRUST LTD (THE) as trustee of the WELLCOME TRUST | 3.31M | $6.45M | $529.5K | Added$529.5K |
| MILLENNIUM MANAGEMENT LLC | 2.75M | $5.37M | $440.8K | Cut−$1.1M |
| ICONIQ Capital, LLC | 2.56M | $4.99M | $409.5K | Added$409.5K |
| Lunate Capital Ltd | 2.12M | $4.14M | $339.9K | Added$339.9K |
| BlackRock, Inc. | 2.05M | $4.01M | $324K | Added$381.3K |
| TWO SIGMA INVESTMENTS, LP | 2.04M | $3.97M | $209.2K | Added$1.63M |
| JOHNSON & JOHNSON | 1.85M | $3.61M | $295.9K | Added$295.9K |
| Renaissance Technologies | 1.39M | $2.71M | $222.2K | Added$120.4K |
| Ikarian Capital, LLC | 1.28M | $2.49M | $204.5K | Added$204.5K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.24M | $2.42M | $118.1K | Added$1.1M |
| MARSHALL WACE, LLP | 1.2M | $2.33M | $93.4K | Added$1.29M |
| GEODE CAPITAL MANAGEMENT, LLC | 1.09M | $2.12M | $160.8K | Added$322.9K |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1M | $1.95M | — | New |
| SILVERARC CAPITAL MANAGEMENT, LLC | 818.2K | $1.6M | — | New |
| TUDOR INVESTMENT CORP ET AL | 771.4K | $1.5M | — | New |
| JANE STREET GROUP, LLC | 747.7K | $1.46M | $119.6K | Cut−$562.9K |
| AlphaCore Capital LLC | 638.8K | $1.25M | $102.2K | Added$102.2K |
| Point72 Asset Management, L.P. | 602.4K | $1.17M | $96.4K | Cut−$5.4M |
| GOLDMAN SACHS GROUP INC | 568.3K | $1.11M | $90.9K | Cut−$428.6K |
| VANGUARD FIDUCIARY TRUST CO | 535K | $1.04M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 516.2K | $1.01M | $82K | Added$89.2K |
| FRANKLIN RESOURCES INC | 511.1K | $996.6K | — | New |
| MORGAN STANLEY | 503.8K | $982.4K | $38.2K | Added$555.6K |
| TANG CAPITAL MANAGEMENT LLC | 439.9K | $857.8K | $70.4K | Cut−$873.6K |
| Caption Management, LLC | 412.2K | $803.8K | — | New |
| State Street | 398.7K | $777.5K | $62.2K | Added$81.3K |
| DIMENSIONAL FUND ADVISORS LP | 354.9K | $691.8K | $17.1K | Added$499.8K |
| Citadel | 343.6K | $670K | $55K | Cut−$235.4K |
| BOOTHBAY FUND MANAGEMENT, LLC | 335.3K | $653.8K | $53.6K | Added$53.6K |
| FEDERATED HERMES, INC. | 314.1K | $612.5K | $50.3K | Added$50.3K |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 273.9K | $534K | $43.8K | Cut−$315.3K |
| JPMORGAN CHASE & CO | 274.1K | $529K | $1.47K | Added$510.2K |
| Cerity Partners LLC | 260.4K | $507.8K | $41.7K | Added$15.3K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 225K | $438.8K | $36K | Added$36K |
| XTX Topco Ltd | 221.8K | $432.6K | $18.2K | Added$228.7K |
| Invesco Ltd. | 205.9K | $401.6K | $32.9K | Cut−$5.83K |
| Qube Research & Technologies Ltd | 197.4K | $384.9K | — | New |
| NORTHERN TRUST CORP | 196.9K | $383.9K | $29.7K | Added$52.1K |
| ExodusPoint Capital Management, LP | 191.7K | $373.8K | $28.9K | Added$50K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 184.8K | $360.4K | — | Held |
| BANK OF AMERICA CORP /DE/ | 176.9K | $345K | $16.4K | Added$161.7K |
| Addis & Hill, Inc | 163.4K | $318.6K | $26.1K | Added$26.1K |
| Susquehanna Portfolio Strategies, LLC | 160.3K | $312.6K | $11.5K | Added$183.6K |
| Maniro Ltd | 158.2K | $308.6K | $25.3K | Added$25.3K |
| Squarepoint Ops LLC | 156.2K | $304.6K | $25K | Cut−$28K |
| SkyOak Wealth, LLC | 150K | $292.5K | $16K | Added$113.5K |
| CANADA PENSION PLAN INVESTMENT BOARD | 140.2K | $273.4K | $14.7K | Added$109.2K |
| SIMPLEX TRADING, LLC | 129.2K | $251.9K | — | New |
| EntryPoint Capital, LLC | 110.9K | $216.2K | $17.7K | Cut−$44K |
| Meridian Wealth Management, LLC | 102.4K | $199.7K | $13.8K | Added$45K |
| Stonepine Capital Management, LLC | 100K | $195K | — | New |
| Brevan Howard Capital Management LP | 97.1K | $189.3K | — | New |
| Voleon Capital Management LP | 93.9K | $183K | $5.01K | Added$127K |
| RBF Capital, LLC | 90K | $175.5K | $14.4K | Cut−$12.8K |
| Quadrature Capital Ltd | 85.3K | $166.4K | $1.82K | Added$146K |
| Velan Capital Investment Management LP | 80K | $156K | — | New |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 76.7K | $149.6K | $12.3K | Added$12.3K |
| DAFNA Capital Management LLC | 70K | $136.5K | — | New |
| Vanguard Personalized Indexing Management, LLC | 62K | $121K | $9.93K | Added$4.79K |
| UBS Group AG | 59.6K | $116.2K | $9.53K | Cut−$53.7K |
| Balyasny Asset Management L.P. | 57.6K | $112.4K | — | New |
| Icahn Capital | 56K | $109.2K | $8.96K | Cut−$59.4K |
| OMERS ADMINISTRATION Corp | 50.9K | $99.3K | $8.14K | Cut−$146.5K |
| CITIGROUP INC | 48.8K | $95.1K | $7.01K | Added$16.7K |
| GROUP ONE TRADING LLC | 46K | $89.8K | — | New |
| AMG National Trust Bank | 43.4K | $84.6K | $6.94K | Added$6.94K |
| AMERICAN CENTURY COMPANIES INC | 39.8K | $77.6K | $6.21K | Added$8.11K |
| Bank of New York Mellon Corp | 39.2K | $76.4K | $6.27K | Added$6.27K |
| BARCLAYS PLC | 34.5K | $67.3K | $4.95K | Added$11.9K |
| BNP PARIBAS FINANCIAL MARKETS | 33.5K | $65.4K | $1.98K | Added$43.2K |
| Catalyst Funds Management Pty Ltd | 33.3K | $64.9K | $4.74K | Added$12K |
| ADAR1 Capital Management, LLC | 33.1K | $64.5K | $5.3K | Cut−$26K |
| Jefferies Financial Group Inc. | 33K | $64.4K | $5.29K | Cut−$14.8K |
| Diametric Capital, LP | 32.8K | $63.9K | — | New |
| Vanguard Global Advisers, LLC | 31K | $60.5K | — | Held |
| China Universal Asset Management Co., Ltd. | 29.7K | $57.8K | $4.36K | Added$9.08K |
| SIG BROKERAGE, LP | 27.5K | $53.6K | $4.4K | Cut−$5.74K |
| Atom Investors LP | 23.8K | $46.3K | — | New |
| Legacy Private Trust Co. | 19K | $37K | $3.04K | Added$3.04K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 16K | $31.2K | — | New |
| HBK Sorce Advisory LLC | 17K | $31.2K | −$4.94K | Cut−$4.94K |
| Woodline Partners LP | 15K | $29.2K | $2.39K | Added$2.39K |
| HSBC HOLDINGS PLC | 11.4K | $22.7K | $2.22K | Cut−$4.19K |
| WINTON GROUP Ltd | 10.1K | $19.7K | — | New |
| Mirae Asset Global Investments Co., Ltd. | 8.71K | $17K | $1.3K | Added$2.46K |
| WELLS FARGO & COMPANY/MN | 5.5K | $10.7K | $880 | Cut−$7.17K |
| Walleye Capital LLC | 5.38K | $10.5K | $5 | Added$10.4K |
| Tower Research Capital LLC (TRC) | 4.07K | $7.93K | $651 | Cut−$23.8K |
| GF FUND MANAGEMENT CO. LTD. | 3.74K | $7.29K | $525 | Added$1.41K |
| CWM, LLC | 3.15K | $6.13K | $6.13K | Added$6.13K |
| RHUMBLINE ADVISERS | 2.58K | $5.03K | $413 | Added$413 |
| NISA INVESTMENT ADVISORS, LLC | 1.47K | $2.86K | $235 | Added$235 |
| Physician Wealth Advisors, Inc. | 1.32K | $2.57K | $211 | Added$211 |
| ROYAL BANK OF CANADA | 1.18K | $2K | −$54 | Cut−$3K |
| PNC Financial Services Group, Inc. | 1K | $1.95K | $160 | Added$160 |
| ACADIAN ASSET MANAGEMENT LLC | 381.5K | $738 | $37 | Added$312 |
| EverSource Wealth Advisors, LLC | 298 | $582 | $49 | Added$11 |
| Parallel Advisors, LLC | 279 | $544 | $45 | Added$45 |
| SIGNATUREFD, LLC | 264 | $515 | — | New |
| GSA CAPITAL PARTNERS LLP | 217.9K | $425 | $35 | Cut−$531 |
| HRT FINANCIAL LP | 198.9K | $387 | — | New |
| Fortitude Family Office, LLC | 167 | $326 | $27 | Cut−$1.5K |
| Virtu Financial LLC | 25.5K | $50 | $4 | Cut−$124 |
| Caitong International Asset Management Co., Ltd | 21 | $41 | $1 | Added$32 |
| SBI Securities Co., Ltd. | 18 | $35 | $3 | Added$1 |
| SG Americas Securities, LLC | 17.2K | $33 | $2 | Cut−$85 |
| Capital Advisors, Ltd. LLC | 145 | $0 | $0 | Held |
| Centerpoint Advisors, LLC | 220 | $0 | $0 | Held |