13F

Investor

GREAT POINT PARTNERS LLC

CIK 0001281446 · filed 2026-05-15 · SEC filing

13F book

$435.1M

Positions

39

18 new · 8 sold

Largest name

7.2%

Apogee Therapeutics, Inc. · APGE

Est. mark

$36.1M

Price effect on 21 names still held. Flow $63.7M.
NameTickerSharesValueWeightEst. markChange
Apogee Therapeutics, Inc.APGE374K$31.5M7.2%$3.25MHeld
Vor Biopharma Inc.VOR1.75M$31.2M7.2%$6.52MAdded$13.3M
Zura Bio LtdZURA4.22M$25.1M5.8%$2.71MAdded$5.09M
Amylyx Pharmaceuticals, Inc.AMLX1.75M$24.3M5.6%$3.19MHeld
Nektar TherapeuticsNKTR316.5K$22.8M5.2%$6.25MAdded$13.9M
Sol-Gel Technologies Ltd.SLGL274.4K$21.7M5.0%New
Alumis Inc.ALMS856.1K$18.9M4.3%New
Bright Minds Biosciences Inc.DRUG220K$16.1M3.7%New
Annexon, Inc.ANNX2.5M$13.8M3.2%New
Kalvista Pharmaceuticals Inc675K$13.6M3.1%$2.69MCut$2.51M
Immunovant, Inc.IMVT545.6K$13.6M3.1%−$316.5KCut−$5.51M
Jade Biosciences, Inc.JBIO964.5K$13.6M3.1%−$1.11MAdded$1.11M
Contineum Therapeutics, Inc.CTNM800.2K$10.5M2.4%$1.3MAdded$1.31M
Zenas BioPharma, Inc.ZBIO524.1K$10.2M2.4%New
Neurogene Inc.NGNE500K$10.1M2.3%−$154KAdded$2.87M
Moonlake ImmunotherapeuticsMLTX500K$9.32M2.1%New
Climb Bio, Inc.CLYM1.33M$9.14M2.1%$2.79MAdded$5.22M
Oruka Therapeutics, Inc.ORKA183.3K$8.99M2.1%$3.44MHeld
Eupraxia Pharmaceuticals Inc.EPRX1.2M$8.69M2.0%−$372KHeld
Vera Therapeutics, Inc.VERA199.3K$8.02M1.8%New
Evommune, Inc.EVMN325K$7.47M1.7%$1.91MHeld
Lb Pharmaceuticals IncLBRX300K$7.4M1.7%New
Compass Therapeutics, Inc.CMPX1.35M$7.14M1.6%New
Scynexis IncSCYX7.55M$6.93M1.6%New
Palisade Bio, Inc.PALI3.41M$5.96M1.4%New
Context Therapeutics Inc.CNTX2.24M$5.86M1.3%$2.57MCut−$1.02M
Relmada Therapeutics, Inc.RLMD842.1K$5.86M1.3%New
Silence Therapeutics Plc1.02M$5.38M1.2%−$654.5KAdded$465.1K
Unicycive Therapeutics, Inc.UNCY796.6K$5.24M1.2%$645.2KHeld
Tenax Therapeutics, Inc.TENX327.3K$5.23M1.2%New
ProMIS Neurosciences Inc.PMN371.4K$4.72M1.1%New
Cullinan Therapeutics, Inc.CGEM300K$4.26M1.0%$1.16MCut−$2.3M
Immix Biopharma, Inc.IMMX350K$3.19M0.7%New
Rezolute, Inc.RZLT951.8K$2.9M0.7%$656.7KHeld
Pharvaris N.V.PHVS82.8K$2.34M0.5%$41.4KHeld
Humacyte Inc3.75M$2.28M0.5%New
Avalo Therapeutics, Inc.AVTX124.7K$1.86M0.4%−$402.7KHeld
Alkermes plc.ALKS50K$1.77M0.4%New
Opus Genetics, Inc.IRD324.3K$1.48M0.3%New

Positions as of Q1 2026. 13F filings arrive up to 45 days after quarter-end and omit shorts. Values are quarter-end marks, as filed. Estimated mark is the price effect on shares still held — not realized P&L or investment advice.