13F

Investor

VR ADVISER, LLC

CIK 0001615982 · filed 2026-05-15 · SEC filing

13F book

$2.68B

Positions

33

8 new · 2 sold

Largest name

26.7%

Apogee Therapeutics, Inc. · APGE

Est. mark

$469.4M

Price effect on 25 names still held. Flow $185.2M.
NameTickerSharesValueWeightEst. markChange
Apogee Therapeutics, Inc.APGE8.49M$714.9M26.7%$73.8MHeld
Erasca, Inc.ERAS16.4M$265.1M9.9%$204.1MCut$198.6M
Oruka Therapeutics, Inc.ORKA4.15M$203.5M7.6%$77.7MHeld
Spyre Therapeutics, Inc.SYRE3.69M$185.9M6.9%$65.2MHeld
Kalvista Pharmaceuticals Inc6.47M$130.3M4.9%$25.8MCut$21.7M
Dianthus Therapeutics Inc1.18M$99M3.7%$42.7MAdded$57.8M
Galecto IncDMRA3.6M$93.3M3.5%New
Ocular Therapeutix, IncOCUL10.3M$87.6M3.3%−$26.8MAdded−$1.17M
Cogent Biosciences, Inc.COGT2M$77M2.9%$5.94MHeld
Viridian Therapeutics Inc3.88M$75.9M2.8%−$44.9MHeld
Savara IncSVRA13.7M$75M2.8%−$7.83MHeld
Enliven Therapeutics, Inc.ELVN1.73M$67.7M2.5%$41.1MCut$18M
Oric Pharmaceuticals, Inc.ORIC4.32M$54.7M2.0%$19.4MCut$8.3M
Vor Biopharma Inc.VOR3.04M$54.3M2.0%$9.25MAdded$28.8M
Maze Therapeutics, Inc.MAZE1.6M$47.8M1.8%−$17.9MAdded−$16.3M
CytomX Therapeutics, Inc.CTMX9.98M$46.9M1.8%$4.39MCut−$19.4M
Jade Biosciences, Inc.JBIO3.22M$45.2M1.7%−$4.44MHeld
Dyne Therapeutics, Inc.DYN2.17M$39.4M1.5%−$3.11MHeld
Crescent Biopharma, Inc.CBIO2.13M$39.2M1.5%$13.9MHeld
Zura Bio LtdZURA6.43M$38.3M1.4%$3.8MAdded$10.3M
Relmada Therapeutics, Inc.RLMD4.84M$33.7M1.3%New
Engene Holdings Inc4.77M$32.5M1.2%−$10.6MHeld
Tenax Therapeutics, Inc.TENX1.68M$26.8M1.0%New
Adlai Nortye Ltd.ANL3.21M$22.2M0.8%New
Century Therapeutics, Inc.IPSC8.7M$19.7M0.7%New
Cullinan Therapeutics, Inc.CGEM1.38M$19.6M0.7%$5.33MHeld
Cybin Inc.HELP3.85M$18.5M0.7%−$13MAdded−$12.9M
Surrozen Inc632.9K$18.4M0.7%$4.13MHeld
Septerna, Inc.SEPN506.1K$12.2M0.5%−$1.95MCut−$4.87M
Korro Bio, Inc.KRRO1.01M$11.4M0.4%New
Alto Neuroscience, Inc.ANRO500K$11.2M0.4%New
Artiva Biotherapeutics, Inc.ARTV1.61M$10.4M0.4%$3.46MHeld
X4 Pharmaceuticals, IncXFOR330.5K$1.37M0.1%New

Positions as of Q1 2026. 13F filings arrive up to 45 days after quarter-end and omit shorts. Values are quarter-end marks, as filed. Estimated mark is the price effect on shares still held — not realized P&L or investment advice.