13F

Investor

EcoR1 Capital, LLC

CIK 0001587114 · filed 2026-05-15 · SEC filing

13F book

$2.36B

Positions

29

10 new · 9 sold

Largest name

24.4%

Zymeworks Inc. · ZYME

Est. mark

$80.4M

Price effect on 19 names still held. Flow $68.7M.
NameTickerSharesValueWeightEst. markChange
Zymeworks Inc.ZYME23M$575.2M24.4%−$29.6MHeld
Anaptysbio, IncANAB7.88M$437M18.5%$55MHeld
Jazz Pharmaceuticals PlcJAZZ1.71M$322.6M13.7%$32.5MHeld
Centessa Pharmaceuticals Plc6M$238.3M10.1%$45.8MAdded$160.4M
Crinetics Pharmaceuticals In4.29M$155.7M6.6%−$43.9MHeld
Aktis Oncology, Inc.AKTS4.82M$86.3M3.7%New
Oric Pharmaceuticals, Inc.ORIC6.73M$85.2M3.6%$30.2MHeld
CG Oncology, Inc.CGON1.1M$74.6M3.2%$20.2MAdded$42.5M
Crispr Therapeutics AgCRSP1.39M$66.1M2.8%−$6.77MHeld
Eton Pharmaceuticals, Inc.ETON2.17M$53.6M2.3%$15.8MAdded$19.3M
Galapagos Nv1.67M$50M2.1%−$4.5MHeld
Xencor IncXNCR2.18M$26.3M1.1%−$7.09MCut−$23.4M
Neurogene Inc.NGNE1.27M$25.6M1.1%−$559.4KHeld
Bridgebio Oncology Therapeut2.82M$25.3M1.1%−$10.1MHeld
MBX Biosciences, Inc.MBX777K$23.2M1.0%−$1.31MCut−$43.8M
Relay Therapeutics, Inc.RLAY1.9M$19M0.8%New
Zenas BioPharma, Inc.ZBIO789.5K$15.4M0.7%−$13.2MHeld
Erasca, Inc.ERAS900K$14.6M0.6%New
Eikon Therapeutics, Inc.EIKN732.6K$7.75M0.3%New
Replimune Group, Inc.REPL1M$7.65M0.3%New
Zura Bio LtdZURA1.18M$7.02M0.3%New
Phathom Pharmaceuticals, Inc.PHAT625K$6.94M0.3%New
Mereo Biopharma Group PlcMREO13.4M$4.41M0.2%−$681.2KAdded$1.14M
Stoke Therapeutics, Inc.STOK100K$3.26M0.1%New
Prelude Therapeutics IncPRLD947K$3.24M0.1%New
iBio, Inc.IBIO1.58M$3.01M0.1%−$47.5KCut−$1.29M
Helix Acquisition Corp. IIIHLXC200K$2.03M0.1%New
Atara Biotherapeutics, Inc.ATRA99.6K$471.1K0.0%−$1.33MCut−$9.9M
Surrozen Inc4.44K$129.5K0.0%$29KHeld

Positions as of Q1 2026. 13F filings arrive up to 45 days after quarter-end and omit shorts. Values are quarter-end marks, as filed. Estimated mark is the price effect on shares still held — not realized P&L or investment advice.