| EcoR1 Capital, LLC | 7.88M | $437M | $55M | Added$55M |
| BlackRock, Inc. | 1.68M | $93.2M | $11.7M | Added$9.16M |
| TANG CAPITAL MANAGEMENT LLC | 1.33M | $73.8M | $9.29M | Added$9.23M |
| MORGAN STANLEY | 993.9K | $55.1M | $6.94M | Added$4.97M |
| State Street | 992.4K | $55M | $6.93M | Added$3.97M |
| Affinity Asset Advisors, LLC | 940K | $52.1M | $3.1M | Added$30.6M |
| VANGUARD CAPITAL MANAGEMENT LLC | 853.2K | $47.3M | — | Held |
| Palo Alto Investors LP | 638.2K | $35.4M | $4.45M | Added$1.94M |
| 683 Capital Management, LLC | 625K | $34.7M | $4.36M | Added$3.24M |
| D. E. Shaw & Co., Inc. | 579.3K | $32.1M | $4.04M | Cut−$367.8K |
| First Light Asset Management, LLC | 565.4K | $31.4M | $3.95M | Added$29.2K |
| Sanofi | 821.9K | $30.4M | −$9.46M | Cut−$9.46M |
| GEODE CAPITAL MANAGEMENT, LLC | 520.2K | $28.9M | $3.28M | Added$6.09M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 519.9K | $28.8M | — | Held |
| BANK OF AMERICA CORP /DE/ | 501.1K | $27.8M | $912.8K | Added$21.5M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 492.1K | $27.3M | $3.43M | Added$156.6K |
| MILLENNIUM MANAGEMENT LLC | 475.6K | $26.4M | $3.32M | Cut−$13.1M |
| Fidelity | 472.7K | $26.2M | $189.2K | Added$24.9M |
| TWO SIGMA INVESTMENTS, LP | 465.1K | $25.8M | $1.79M | Added$13.4M |
| FEDERATED HERMES, INC. | 364.1K | $20.2M | $2.09M | Added$5.68M |
| Woodline Partners LP | 344.3K | $19.1M | $2.4M | Cut−$5.2M |
| GOLDMAN SACHS GROUP INC | 332.7K | $18.5M | $2.32M | Cut−$885.4K |
| Synergy Asset Management, LLC | 317.1K | $17.6M | — | New |
| Nuveen, LLC | 316.1K | $17.5M | $2.21M | Added$2.18M |
| Squarepoint Ops LLC | 267.7K | $14.8M | $1.12M | Added$7.05M |
| Qube Research & Technologies Ltd | 254.7K | $14.1M | $760.6K | Added$8.85M |
| Sofinnova Investments, Inc. | 248.3K | $13.8M | $1.73M | Cut−$179.1K |
| Apis Capital Advisors, LLC | 238K | $13.2M | — | New |
| Citadel | 233.4K | $12.9M | $764.2K | Added$7.64M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 192.7K | $10.7M | $1.34M | Added$1.06M |
| NORTHERN TRUST CORP | 183.5K | $10.2M | $1.27M | Added$1.36M |
| Connor, Clark & Lunn Investment Management Ltd. | 158.6K | $8.79M | $854.9K | Added$2.86M |
| VANGUARD FIDUCIARY TRUST CO | 135.1K | $7.49M | — | Held |
| HSBC HOLDINGS PLC | 125.7K | $7.14M | — | New |
| Ensign Peak Advisors, Inc | 125.6K | $6.97M | $876.9K | Cut−$3.48M |
| Invesco Ltd. | 121.1K | $6.72M | $845.3K | Added$704.6K |
| VICTORY CAPITAL MANAGEMENT INC | 108.2K | $6M | $755.3K | Added$639.9K |
| BNP PARIBAS FINANCIAL MARKETS | 97K | $5.38M | $676.9K | Cut−$2.61M |
| HighMark Wealth Management LLC | 94K | $5.22M | $656.5K | Added$656.5K |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 93.7K | $5.2M | $654K | Added$654K |
| Renaissance Technologies | 90.9K | $5.04M | $532.6K | Added$1.34M |
| JANE STREET GROUP, LLC | 86K | $4.77M | $589.4K | Added$677.7K |
| Trexquant Investment LP | 85.2K | $4.72M | $410.5K | Added$1.87M |
| UBS Group AG | 79.7K | $4.42M | $488.8K | Added$1.02M |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 79K | $4.38M | $551.1K | Cut−$6.73M |
| CITIGROUP INC | 73.4K | $4.07M | $512.4K | Added$510.1K |
| MARSHALL WACE, LLP | 68K | $3.77M | — | New |
| Granahan Investment Management, LLC | 66.2K | $3.67M | $462K | Cut−$2.43M |
| FRANKLIN RESOURCES INC | 65.8K | $3.65M | — | New |
| PRUDENTIAL FINANCIAL INC | 64K | $3.55M | — | New |
| Fisher Asset Management, LLC | 56.6K | $3.14M | $394.8K | Added$396.6K |
| Point72 Asset Management, L.P. | 55.3K | $3.07M | $386K | Cut−$90.6M |
| DEUTSCHE BANK AG\ | 52K | $2.89M | $100.4K | Added$2.19M |
| Bank of New York Mellon Corp | 51.1K | $2.83M | $356.8K | Added$151.7K |
| XTX Topco Ltd | 50.5K | $2.8M | $269.7K | Added$929.7K |
| WELLINGTON MANAGEMENT GROUP LLP | 46.9K | $2.6M | $327.2K | Cut−$366.3K |
| Bleakley Financial Group, LLC | 43.1K | $2.39M | $301K | Added$280.3K |
| Moody Aldrich Partners LLC | 39.5K | $2.19M | $275.4K | Cut−$119.5K |
| Tidal Investments LLC | 36.4K | $2.02M | — | New |
| Susquehanna Portfolio Strategies, LLC | 35.9K | $1.99M | $250.9K | Added$250.9K |
| MACKENZIE FINANCIAL CORP | 33.7K | $1.87M | $177.5K | Added$703.9K |
| WELLS FARGO & COMPANY/MN | 33.2K | $1.84M | $155K | Added$763.6K |
| Icahn Capital | 32.5K | $1.8M | $183.6K | Added$525.2K |
| TEMA ETFS LLC | 31.1K | $1.72M | $157.5K | Added$629.4K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 30.7K | $1.7M | $212.9K | Added$225.1K |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 28.6K | $1.59M | $199.8K | Cut−$1.08M |
| MARTINGALE ASSET MANAGEMENT L P | 28.1K | $1.56M | — | New |
| Engineers Gate Manager LP | 27.8K | $1.54M | $75.9K | Added$1.02M |
| STATE OF WISCONSIN INVESTMENT BOARD | 27.6K | $1.53M | $62.5K | Added$1.1M |
| Swiss National Bank | 27.6K | $1.53M | $192.6K | Added$192.6K |
| ALLIANCEBERNSTEIN L.P. | 31.3K | $1.52M | −$0 | Added$38.8K |
| Rafferty Asset Management, LLC | 27.2K | $1.51M | $190.2K | Cut−$200.6K |
| Eversept Partners, LP | 27.1K | $1.5M | $189.1K | Cut−$4.36M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 26.6K | $1.47M | — | New |
| Headlands Technologies LLC | 24.6K | $1.36M | $171.4K | Added$136.5K |
| RHUMBLINE ADVISERS | 23.8K | $1.32M | $166.5K | Added$109.1K |
| Y-Intercept (Hong Kong) Ltd | 22.7K | $1.26M | $158.5K | Cut−$345.7K |
| J. Goldman & Co LP | 21.2K | $1.18M | — | New |
| HUSSMAN STRATEGIC ADVISORS, INC. | 21K | $1.16M | — | New |
| CREDIT AGRICOLE S A | 20K | $1.11M | $139.6K | Cut−$830K |
| DCF Advisers, LLC | 18.8K | $1.04M | $131.1K | Cut−$667.7K |
| Walleye Capital LLC | 18.4K | $1.02M | — | New |
| PDT Partners, LLC | 17.6K | $975.8K | $122.8K | Cut−$1.11M |
| Creative Planning | 16.8K | $933.7K | $106.5K | Added$194.2K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 15.7K | $868.7K | $286.8K | Added$318K |
| CANADA PENSION PLAN INVESTMENT BOARD | 14.9K | $826.4K | — | New |
| TWINBEECH CAPITAL LP | 14.5K | $805.2K | — | New |
| VOYA INVESTMENT MANAGEMENT LLC | 14.3K | $795.6K | $89.1K | Added$177K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 14K | $776.4K | $97.7K | Added$91K |
| Gotham Asset Management, LLC | 14K | $774.9K | — | New |
| Cresset Asset Management, LLC | 13.9K | $769.1K | $96.8K | Added$36.1K |
| Legal & General Group Plc | 13.8K | $767.1K | $96.5K | Cut−$114.3K |
| Brookwood Investment Group LLC | 13.4K | $741.1K | — | New |
| Russell Investments Group, Ltd. | 13.3K | $737K | $92.7K | Cut−$218.8K |
| Orion Porfolio Solutions, LLC | 13.1K | $728.1K | $91.6K | Added$15.6K |
| OXFORD ASSET MANAGEMENT LLP | 12.7K | $703K | — | New |
| PROFUND ADVISORS LLC | 12.2K | $676.7K | $85.2K | Added$42.2K |
| Vanguard Global Advisers, LLC | 11.8K | $651.9K | — | Held |
| JPMORGAN CHASE & CO | 11.6K | $645K | $75.4K | Added$115.8K |
| Brevan Howard Capital Management LP | 11K | $611.6K | — | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 10.5K | $581.4K | $73.6K | Added$66.1K |
| MetLife Investment Management, LLC | 10.2K | $564.2K | $71K | Added$63.5K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 10.2K | $563.8K | $39.7K | Added$288.3K |
| VANGUARD ASSET MANAGEMENT, Ltd | 9.69K | $537.4K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9.6K | $532.4K | $64.8K | Added$82.2K |
| SEI INVESTMENTS CO | 7.65K | $424.5K | $34.7K | Added$183.7K |
| Ground Swell Capital, LLC | 7.61K | $422.1K | — | New |
| JANUS HENDERSON GROUP PLC | 7.46K | $413.9K | $51.7K | Added$51.7K |
| BARCLAYS PLC | 7.44K | $412.6K | $51.9K | Cut−$2.48M |
| ExodusPoint Capital Management, LP | 7.26K | $402.6K | $50.7K | Cut−$3.64M |
| NEW YORK STATE COMMON RETIREMENT FUND | 6.99K | $387.6K | $48.8K | Cut−$53K |
| Duncan Williams Asset Management, LLC | 6.53K | $361.9K | $46.2K | Added$46.2K |
| Vinva Investment Management Ltd | 4.38K | $354.2K | — | New |
| GLENMEDE TRUST CO NA | 6.38K | $353.9K | $44.5K | Cut−$2.24K |
| Savant Capital, LLC | 6.17K | $342.4K | $43.1K | Added$37.2K |
| China Universal Asset Management Co., Ltd. | 6.16K | $341.9K | $43K | Cut−$22.3K |
| Quantinno Capital Management LP | 6.08K | $337.4K | $42.5K | Added$25.5K |
| Virtus Investment Advisers, LLC | 6.07K | $336.5K | $41.3K | Added$49.5K |
| Soleus Capital Management, L.P. | 6K | $332.8K | $41.9K | Cut−$6.21M |
| ENVESTNET ASSET MANAGEMENT INC | 5.85K | $324.5K | $40.8K | Added$28.9K |
| Ascent Group, LLC | 5.62K | $311.8K | $39.2K | Added$37.3K |
| Integrated Quantitative Investments LLC | 5.61K | $310.9K | — | New |
| FMB WEALTH MANAGEMENT | 5.59K | $310.1K | $39K | Added$39K |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 5.53K | $306.5K | $38.6K | Added$38.6K |
| Bayforest Capital Ltd | 5.24K | $290.8K | — | New |
| INTECH INVESTMENT MANAGEMENT LLC | 5.09K | $282.1K | $35.5K | Cut−$53.5K |
| TUDOR INVESTMENT CORP ET AL | 4.96K | $275.2K | $34.6K | Cut−$563.8K |
| Police & Firemen's Retirement System of New Jersey | 4.94K | $273.8K | $34.5K | Added$330 |
| Balyasny Asset Management L.P. | 4.91K | $272K | — | New |
| State of New Jersey Common Pension Fund D | 4.78K | $265.3K | — | New |
| AXQ CAPITAL, LP | 4.71K | $261.5K | — | New |
| Hillsdale Investment Management Inc. | 4.62K | $256.2K | — | New |
| Latash Investments, LLC | 4.39K | $243.6K | $30.7K | Added$30.7K |
| Dynamic Technology Lab Private Ltd | 4.36K | $241.8K | — | New |
| ROYAL BANK OF CANADA | 4.22K | $234K | $12.3K | Added$151K |
| Allen Capital Group, LLC | 4.12K | $228.7K | — | New |
| Moran Wealth Management, LLC | 4.06K | $225.4K | — | New |
| Jump Financial, LLC | 3.9K | $216.3K | $27.2K | Cut−$5.61M |
| ProShare Advisors LLC | 3.88K | $215.4K | $27.1K | Cut−$7.5K |
| ARIZONA STATE RETIREMENT SYSTEM | 3.85K | $213.2K | — | New |
| MANGROVE PARTNERS IM, LLC | 3.71K | $205.6K | — | New |
| ADAR1 Capital Management, LLC | 3.7K | $205.1K | — | New |
| Vanguard Investments Australia, Ltd. | 3.58K | $198.3K | — | Held |
| KLP KAPITALFORVALTNING AS | 3K | $166.4K | $20.9K | Added$20.9K |
| Tower Research Capital LLC (TRC) | 2.9K | $160.7K | $5.07K | Added$125.5K |
| Caitong International Asset Management Co., Ltd | 2.33K | $129.2K | $10.7K | Added$55K |
| OSAIC HOLDINGS, INC. | 2.05K | $113.5K | $14.3K | Cut−$1.23M |
| Aster Capital Management (DIFC) Ltd | 5.22K | $97K | −$3.74K | Added$90.9K |
| US BANCORP \DE\ | 1.64K | $90.7K | $11.4K | Added$11.1K |
| Larson Financial Group LLC | 1.63K | $90.2K | $11.3K | Added$11.4K |
| Ameritas Investment Partners, Inc. | 1.49K | $82.9K | $10.4K | Added$3.01K |
| CWM, LLC | 1.01K | $56.3K | $56K | Added$56.2K |
| Mirae Asset Global Investments Co., Ltd. | 1.44K | $53.4K | −$15.5K | Cut−$11.8K |
| EverSource Wealth Advisors, LLC | 903 | $50.1K | $6.11K | Added$7.66K |
| Smartleaf Asset Management LLC | 840 | $46.5K | $5.98K | Added$6.26K |
| SBI Securities Co., Ltd. | 788 | $43.7K | $5.5K | Cut−$45.2K |
| NISA INVESTMENT ADVISORS, LLC | 649 | $36K | $4.53K | Cut−$10.7K |
| GF FUND MANAGEMENT CO. LTD. | 621 | $34.4K | $3.79K | Added$8.12K |
| Quantbot Technologies LP | 559 | $31K | — | New |
| Versant Capital Management, Inc | 454 | $25.2K | $3.17K | Added$3.17K |
| GAMMA Investing LLC | 442 | $24.5K | $2.68K | Added$5.9K |
| Spire Wealth Management | 400 | $22.2K | — | New |
| Farther Finance Advisors, LLC | 384 | $21.8K | $3.17K | Added$3.17K |
| SIGNATUREFD, LLC | 366 | $20.3K | $2.46K | Added$3.23K |
| GROUP ONE TRADING LLC | 365 | $20.2K | — | New |
| Pinnacle Wealth Planning Services, Inc. | 334 | $18.5K | $2.33K | Added$2.33K |
| NATIXIS | 333 | $18.5K | — | New |
| Rockefeller Capital Management L.P. | 326 | $18.1K | $454 | Added$14.9K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 257 | $14.3K | $13.2K | Added$14.2K |
| MEEDER ASSET MANAGEMENT INC | 240 | $13.3K | — | New |
| QUADRANT CAPITAL GROUP LLC | 177 | $9.82K | $1.22K | Added$1.33K |
| ROTHSCHILD INVESTMENT LLC | 165 | $9.15K | $1.15K | Added$1.15K |
| Allworth Financial LP | 154 | $8.54K | $998 | Added$1.61K |
| Sterling Capital Management LLC | 118 | $6.54K | $809 | Added$920 |
| PNC Financial Services Group, Inc. | 109 | $6.04K | $726 | Added$1K |
| Physician Wealth Advisors, Inc. | 85 | $4.71K | $594 | Added$594 |
| Wall Street Financial Group, Inc. | 75 | $4.16K | — | New |
| Parallel Advisors, LLC | 66 | $3.66K | $384 | Added$994 |
| HOLLENCREST CAPITAL MANAGEMENT | 50 | $2.77K | — | New |
| MassMutual Private Wealth & Trust, FSB | 46 | $2.55K | $83 | Added$1.97K |
| Penserra Capital Management LLC | 43.4K | $2.41K | $303 | Cut−$323 |
| Steward Partners Investment Advisory, LLC | 43 | $2.38K | $300 | Added$300 |
| HRT FINANCIAL LP | 40.5K | $2.25K | $283 | Cut−$3.7K |
| ASSETMARK, INC | 36 | $2K | $252 | Added$252 |
| Virtu Financial LLC | 33.3K | $1.85K | — | New |
| Essential Partners LLC | 33 | $1.83K | $230 | Added$230 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 29.7K | $1.65K | $182 | Added$386 |
| Parkside Financial Bank & Trust | 25 | $1.39K | $175 | Added$175 |
| SG Americas Securities, LLC | 24.9K | $1.38K | $72 | Added$872 |
| Blue Trust, Inc. | 19 | $1.05K | $133 | Added$133 |
| Root Financial Partners, LLC | 16 | $887 | — | New |
| ACADIAN ASSET MANAGEMENT LLC | 13.2K | $730 | $41 | Added$450 |
| Stone House Investment Management, LLC | 12 | $666 | $84 | Added$36 |
| MAI Capital Management | 11 | $611 | $70 | Added$126 |
| Fortitude Family Office, LLC | 8 | $444 | — | New |
| TWIN PEAKS WEALTH ADVISORS, LLC | 5 | $277 | — | New |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 4.86K | $270 | $34 | Added$34 |
| Sunbelt Securities, Inc. | 4 | $222 | $28 | Added$28 |
| True Wealth Design, LLC | 4 | $222 | $28 | Added$28 |
| Advisory Services Network, LLC | 3 | $166 | — | New |
| BESSEMER GROUP INC | 1.43K | $79 | $10 | Added$8 |
| TFC Financial Management, Inc. | 1 | $56 | $7 | Added$7 |
| Keating Financial Advisory Services, Inc. | 1 | $55 | — | New |
| IFP Advisors, Inc | 1 | $55 | $7 | Added$7 |
| CANADA LIFE ASSURANCE Co | 750 | $42 | $6 | Added$6 |
| Covestor Ltd | 2 | $0 | $0 | Held |