13F

Investor

SECTORAL ASSET MANAGEMENT INC

CIK 0001274413 · filed 2026-05-15 · SEC filing

13F book

$120.7M

Positions

77

10 new · 7 sold

Largest name

11.2%

Evommune, Inc. · EVMN

Est. mark

$2.91M

Price effect on 67 names still held. Flow −$6.94M.
NameTickerSharesValueWeightEst. markChange
Evommune, Inc.EVMN589K$13.5M11.2%$3.46MHeld
Contineum Therapeutics, Inc.CTNM727.6K$9.5M7.9%$1.19MCut$349.3K
Shoulder Innovations, Inc.SI430.4K$6.25M5.2%$99KCut−$788K
Eli Lilly & CoLLY6.35K$5.84M4.8%−$984.3KCut−$1.98M
Johnson & JohnsonJNJ18.2K$4.45M3.7%$683KCut$252.1K
Gilead Sciences, Inc.GILD27.5K$4.13M3.4%$492.8KAdded$1.94M
Unitedhealth Group IncUNH15K$4.05M3.4%−$809.2KAdded−$440.6K
Amgen IncAMGN9.21K$3.51M2.9%$500.5KCut−$763K
Vertex Pharmaceuticals Inc7.01K$3.46M2.9%$280.4KCut−$172K
Insmed IncINSM19.7K$3.38M2.8%−$24KAdded$1.43M
Argenx SEARGX3.56K$2.74M2.3%−$211.3KAdded$303.3K
AbbVie Inc.ABBV12.2K$2.65M2.2%−$134.2KCut−$1.19M
Abbott LabsABT25.6K$2.63M2.2%−$531.5KAdded−$318K
Merck & Co., Inc.MRK21.5K$2.58M2.1%$321.6KAdded$331.3K
Regeneron Pharmaceuticals, Inc.REGN2.92K$2.48M2.1%$228.6KCut−$385.8K
Intuitive Surgical IncISRG5.25K$2.42M2.0%−$511KAdded−$326.6K
Boston Scientific CorpBSX34.8K$2.18M1.8%−$900.6KAdded−$451.7K
Biontech SeBNTX22.2K$2.05M1.7%−$50.3KAdded$406.2K
Stryker CorpSYK5.87K$1.93M1.6%−$134.4KCut−$372K
Danaher Corporation9.6K$1.82M1.5%−$377.4KCut−$601.2K
Thermo Fisher Scientific Inc.TMO3.51K$1.72M1.4%−$308.4KCut−$535.6K
Dexcom IncDXCM23.2K$1.46M1.2%−$82.9KCut−$445.9K
Iqvia Hldgs Inc8.31K$1.42M1.2%New
Summit Therapeutics Inc.SMMT69.6K$1.4M1.2%$182.1KCut$6.99K
Edwards Lifesciences CorpEW17.3K$1.39M1.1%−$89.2KAdded−$82.1K
Bristol-Myers Squibb Co21.1K$1.28M1.1%New
United Therapeutics Corp Del1.71K$1.15M0.9%$312.4KCut$306.1K
Vera Therapeutics, Inc.VERA25.6K$1.08M0.9%−$210.4KCut−$781.8K
Arcus Biosciences, Inc.RCUS45.1K$1.04M0.9%−$38.5KCut−$321.5K
Roivant Sciences Ltd.ROIV32.5K$1.02M0.8%$311.1KCut$32.3K
Medtronic PlcMDT11.1K$961.8K0.8%New
Trevi Therapeutics, Inc.TRVI74.4K$939.5K0.8%$7.43KCut−$115.4K
Cogent Biosciences, Inc.COGT22.1K$902.4K0.7%$116KCut−$258.6K
Mineralys Therapeutics, Inc.MLYS31.6K$895.1K0.7%−$252.3KCut−$252.5K
Alnylam Pharmaceuticals, Inc.ALNY2.31K$864.2K0.7%−$54.3KCut−$324.7K
Tarsus Pharmaceuticals, Inc.TARS11.3K$852.5K0.7%−$70.5KCut−$354.4K
Rapport Therapeutics, Inc.RAPP25.4K$835K0.7%$63.7KCut−$346K
Nektar TherapeuticsNKTR10.9K$820.7K0.7%$361.9KCut$250.5K
Syndax Pharmaceuticals IncSNDX31.7K$787.5K0.7%$121.9KCut−$498.3K
Ardelyx, Inc.ARDX122.4K$781.1K0.6%New
Pfizer IncPFE27.5K$772.2K0.6%$86.3KAdded$96.2K
Boundless Bio, Inc.BOLD678.6K$746.4K0.6%−$67.9KHeld
Ascendis Pharma A/SASND2.8K$728.3K0.6%$131.2KCut$34.4K
ArriVent BioPharma, Inc.AVBP30K$720.4K0.6%$116.6KCut−$49.3K
Structure Therapeutics Inc.GPCR14.1K$710.8K0.6%−$270KCut−$949.5K
Immatics N.V.IMTX66.8K$692.7K0.6%−$8.51KAdded$31K
BridgeBio Pharma, Inc.BBIO8.1K$687.3K0.6%$67.7KCut−$167.1K
ARS Pharmaceuticals, Inc.SPRY79.2K$676.7K0.6%−$92.4KAdded$329.5K
Beone Medicines Ltd1.87K$631.1K0.5%$62.9KCut−$178.6K
Tectonic Therapeutic, Inc.TECX19.1K$628.2K0.5%$230.6KCut−$253.2K
Ionis Pharmaceuticals IncIONS7.2K$617.2K0.5%$47.6KCut−$44.5K
Biomarin Pharmaceutical IncBMRN9.45K$607.3K0.5%$45.7KCut−$39.3K
Kura Oncology, Inc.KURA71.5K$606K0.5%−$103.5KAdded$43.8K
Privia Health Group, Inc.PRVA27.1K$558.2K0.5%−$81.6KAdded−$58.3K
Cytokinetics IncCYTK7.3K$544.6K0.5%$65.2KAdded$170.2K
Ptc Therapeutics, Inc.PTCT6.65K$515.1K0.4%$9.93KCut−$71K
Uniqure Nv29.2K$499.4K0.4%−$200.4KCut−$232.5K
Agomab Therapeutics NvAGMB43.5K$477.3K0.4%New
Alignment Healthcare, Inc.ALHC26.9K$474.2K0.4%−$57.3KCut−$148K
Hinge Health, Inc.HNGE12.2K$472.1K0.4%−$96.6KCut−$187.7K
RadNet, Inc.RDNT8K$447.1K0.4%−$123.7KCut−$337.8K
Royalty Pharma PLCRPRX7.2K$393.8K0.3%$115.6KCut$66.6K
Biogen Inc.BIIB1.85K$385.9K0.3%$60.3KCut$6.65K
Inspire Med Sys Inc7.22K$372.7K0.3%−$292.7KAdded−$291.4K
Jazz Pharmaceuticals PlcJAZZ1.75K$371.3K0.3%$73.8KCut$23K
Neurocrine Biosciences IncNBIX2.3K$343.8K0.3%$17.6KCut−$35.6K
Oric Pharmaceuticals, Inc.ORIC23.5K$332.7K0.3%$134.3KAdded$148.8K
Omada Health, Inc.OMDA25.6K$322K0.3%−$82.2KCut−$253.9K
Abivax Sa2.34K$297.9K0.2%New
Illumina, Inc.ILMN2.13K$296.1K0.2%$16.4KCut−$28.2K
Axsome Therapeutics, Inc.AXSM1.5K$289.9K0.2%$15.9KCut−$27.9K
Incyte CorpINCY2.35K$254.1K0.2%$22KCut−$17.5K
Moderna, Inc.MRNA4.35K$247.9K0.2%$119.6KCut$100.3K
Medpace Hldgs Inc430$228.1K0.2%New
Guardant Health, Inc.GH1.98K$205.5K0.2%New
Revolution Medicines Inc1.83K$202.3K0.2%New
Palisade Bio, Inc.PALI88K$172.4K0.1%New

Positions as of Q1 2026. 13F filings arrive up to 45 days after quarter-end and omit shorts. Values are quarter-end marks, as filed. Estimated mark is the price effect on shares still held — not realized P&L or investment advice.