13F

Investor

Casdin Capital, LLC

CIK 0001534261 · filed 2026-05-15 · SEC filing

13F book

$1.32B

Positions

40

9 new · 7 sold

Largest name

19.0%

Revolution Medicines Inc

Est. mark

−$248.6M

Price effect on 31 names still held. Flow −$40.8M.
NameTickerSharesValueWeightEst. markChange
Revolution Medicines Inc2.58M$250.6M19.0%$45.4MHeld
GeneDx Holdings Corp.WGS3.01M$193.1M14.6%−$198MHeld
Relay Therapeutics, Inc.RLAY14.4M$143.5M10.9%$19.4MAdded$33.5M
Biolife Solutions IncBLFS5.96M$113.7M8.6%−$30.4MHeld
Standard Biotools Inc.LAB88.8M$81.6M6.2%−$32MHeld
Illumina, Inc.ILMN530K$65.3M4.9%−$4.19MCut−$13.4M
Structure Therapeutics Inc.GPCR1.18M$56.6M4.3%−$25.1MHeld
10x Genomics, Inc.TXG2.27M$48.3M3.7%$6.89MAdded$25.5M
Denali Therapeutics Inc.DNLI1.84M$35.3M2.7%$4.95MHeld
Beam Therapeutics Inc.BEAM1.35M$32.2M2.4%−$5.25MCut−$12.2M
Guardant Health, Inc.GH315K$29.1M2.2%−$3.08MCut−$9.72M
Neurogene Inc.NGNE1.42M$28.6M2.2%−$570KAdded$1.95M
Alnylam Pharmaceuticals, Inc.ALNY75K$24.8M1.9%−$5.01MHeld
Maze Therapeutics, Inc.MAZE758.9K$22.7M1.7%−$8.79MHeld
Scholar Rock Hldg Corp350K$17.2M1.3%$1.33MAdded$5.75M
Agomab Therapeutics NvAGMB1.55M$16.3M1.2%New
Hims & Hers Health, Inc.HIMS700K$14.5M1.1%−$4.51MAdded$2.03M
Taysha Gene Therapies, Inc.TSHA3.25M$14.5M1.1%−$1.55MAdded$6.28M
Qiagen Nv Ord Shares360K$14.4M1.1%New
Tempus AI, Inc.TEM294.1K$13.3M1.0%−$4.07MHeld
Septerna, Inc.SEPN553.3K$13.3M1.0%−$2.13MHeld
GRAIL, Inc.GRAL230K$11.9M0.9%New
Prime Medicine, Inc.PRME3.17M$11M0.8%$31.7KHeld
Personalis, Inc.PSNL1.6M$10.2M0.8%New
Quest Diagnostics IncDGX50K$9.8M0.7%$1.12MHeld
Veracyte, Inc.VCYT276.3K$8.9M0.7%−$2.73MHeld
Moonlake ImmunotherapeuticsMLTX450K$8.39M0.6%New
Intellia Therapeutics, Inc.NTLA355K$4.55M0.3%New
Disc Medicine, Inc.IRON65K$4.16M0.3%New
Moderna, Inc.MRNA75K$3.81M0.3%New
Adlai Nortye Ltd.ANL538.5K$3.73M0.3%New
Monte Rosa Therapeutics, Inc.GLUE186K$3.06M0.2%$66.2KAdded$1.71M
Absci CorpABSI973.3K$2.92M0.2%−$476.9KHeld
Century Therapeutics, Inc.IPSC1.23M$2.78M0.2%$1.55MHeld
Bridgebio Oncology Therapeut282.3K$2.53M0.2%−$1.01MHeld
Contineum Therapeutics, Inc.CTNM148.3K$1.94M0.1%$241.8KHeld
Pacific Biosciences Calif In723.8K$955.4K0.1%−$398.1KCut−$6.94M
Recursion Pharmaceuticals In165.3K$507.5K0.0%−$168.6KHeld
Tenaya Therapeutics, Inc.TNYA362K$250.6K0.0%−$6.91KHeld
Ginkgo Bioworks Holdings Inc36.5K$223.7K0.0%−$79.6KHeld

Positions as of Q1 2026. 13F filings arrive up to 45 days after quarter-end and omit shorts. Values are quarter-end marks, as filed. Estimated mark is the price effect on shares still held — not realized P&L or investment advice.