| Avoro Capital Advisors LLC | 5.89M | $236.9M | −$61.3M | Cut−$61.3M |
| BlackRock, Inc. | 5.09M | $204.7M | −$50.2M | Cut−$39.7M |
| Deep Track Capital, LP | 4.11M | $165.2M | −$29.4M | Added$22.3M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 3.72M | $149.7M | −$38.7M | Cut−$55.8M |
| Kynam Capital Management, LP | 3.4M | $136.7M | −$35.4M | Cut−$37.1M |
| State Street | 3.36M | $135.3M | −$27.9M | Cut−$223.9K |
| Sofinnova Investments, Inc. | 2.79M | $112.4M | −$29.1M | Cut−$29.1M |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.68M | $108M | — | Held |
| Fidelity | 2.68M | $107.7M | −$27.9M | Cut−$38.5M |
| Eversept Partners, LP | 2.17M | $87.4M | −$22.6M | Cut−$68.2M |
| Bellevue Group AG | 1.71M | $68.8M | −$17.7M | Cut−$17.2M |
| ALLIANCEBERNSTEIN L.P. | 1.31M | $66.6M | $1 | Added$4.84M |
| Integral Health Asset Management, LLC | 1.6M | $64.4M | −$16.7M | Cut−$26.8M |
| GEODE CAPITAL MANAGEMENT, LLC | 1.57M | $63.2M | −$15M | Cut−$10M |
| Vestal Point Capital, LP | 1.37M | $55M | −$5.73M | Added$27.2M |
| Point72 Asset Management, L.P. | 1.21M | $48.7M | −$12.6M | Cut−$39.3M |
| GOLDMAN SACHS GROUP INC | 1.13M | $45.6M | −$11.7M | Cut−$11.1M |
| Pictet Asset Management Holding SA | 1.05M | $42.3M | −$10.9M | Cut−$28.2M |
| Woodline Partners LP | 1M | $40.3M | −$10.4M | Cut−$10.4M |
| AMERICAN CENTURY COMPANIES INC | 728.3K | $29.3M | −$7.58M | Cut−$7.8M |
| BANK OF AMERICA CORP /DE/ | 589.7K | $23.7M | −$6.14M | Cut−$11.4M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 553K | $22.2M | — | Held |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 551.5K | $22.2M | −$3.86M | Added$3.39M |
| Qube Research & Technologies Ltd | 541.8K | $21.8M | −$3.94M | Added$2.65M |
| DEUTSCHE BANK AG\ | 532.5K | $21.4M | −$3.62M | Added$3.83M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 524.6K | $21.1M | −$5.4M | Cut−$5.17M |
| BRAIDWELL LP | 523.8K | $21.1M | −$5.45M | Cut−$18.7M |
| NORTHERN TRUST CORP | 519.4K | $20.9M | −$4.93M | Cut−$3.07M |
| Rock Springs Capital Management LP | 503.6K | $20.3M | −$5.24M | Cut−$8.53M |
| Elmind Capital, LP | 482.5K | $19.4M | −$5.02M | Cut−$5.02M |
| Candriam S.C.A. | 475.3K | $19.1M | −$4.68M | Cut−$3.64M |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 484.4K | $18.5M | −$415.4K | Added$16.8M |
| Renaissance Technologies | 457.3K | $18.4M | −$2.01M | Added$8.6M |
| VANGUARD FIDUCIARY TRUST CO | 441.5K | $17.8M | — | Held |
| Citadel | 429.8K | $17.3M | −$4.47M | Cut−$22.1M |
| First Turn Management, LLC | 422K | $17M | −$4.39M | Cut−$13.5M |
| Balyasny Asset Management L.P. | 419.6K | $16.9M | −$565.5K | Added$14.1M |
| Nuveen, LLC | 398.6K | $16M | −$2.36M | Added$4.54M |
| ORBIMED ADVISORS LLC | 369.6K | $14.9M | −$3.68M | Cut−$3.03M |
| MORGAN STANLEY | 368.8K | $14.8M | −$3.84M | Cut−$10.5M |
| ExodusPoint Capital Management, LP | 317.4K | $12.8M | −$757.2K | Added$9.08M |
| First Light Asset Management, LLC | 313.9K | $12.6M | −$3.27M | Cut−$31.4M |
| ARMISTICE CAPITAL, LLC | 298.2K | $12M | −$3.1M | Cut−$21.1M |
| BNP PARIBAS FINANCIAL MARKETS | 298.1K | $12M | −$3.1M | Cut−$12M |
| MILLENNIUM MANAGEMENT LLC | 293.5K | $11.8M | −$2.08M | Added$1.69M |
| VOYA INVESTMENT MANAGEMENT LLC | 290.5K | $11.7M | −$3.02M | Cut−$9.53M |
| DIMENSIONAL FUND ADVISORS LP | 278.8K | $11.2M | −$2.9M | Cut−$6.6M |
| Affinity Asset Advisors, LLC | 250K | $10.1M | −$2.6M | Cut−$2.6M |
| CITIGROUP INC | 250K | $10.1M | −$1.81M | Added$1.23M |
| Alphabet Inc. | 241.3K | $9.71M | −$2.51M | Cut−$2.51M |
| BARCLAYS PLC | 232.5K | $9.35M | −$2.42M | Cut−$3.49M |
| TimesSquare Capital Management, LLC | 232.5K | $9.35M | −$2.42M | Cut−$3.43M |
| TWO SIGMA INVESTMENTS, LP | 210.2K | $8.45M | −$2.19M | Cut−$2.18M |
| Ikarian Capital, LLC | 200K | $8.05M | — | New |
| GREAT POINT PARTNERS LLC | 199.3K | $8.02M | — | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 197.8K | $7.96M | −$2.06M | Cut−$2.32M |
| TD Asset Management Inc | 194K | $7.8M | −$2.02M | Cut−$8.68M |
| Hudson Bay Capital Management LP | 192.4K | $7.74M | — | New |
| UBS Group AG | 187.9K | $7.56M | −$1.96M | Cut−$2.94M |
| Bank of New York Mellon Corp | 179.4K | $7.22M | −$1.77M | Cut−$1.38M |
| PFM Health Sciences, LP | 174.9K | $7.03M | −$1.12M | Added$1.58M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 153.2K | $6.16M | $6.16M | Added$6.16M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 146.2K | $5.88M | −$1.59M | Cut−$4.75M |
| Freestone Grove Partners LP | 146.1K | $5.88M | — | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 121K | $4.87M | −$1.26M | Cut−$4.08M |
| CANADA PENSION PLAN INVESTMENT BOARD | 120.9K | $4.86M | −$1.26M | Cut−$1.24M |
| Ensign Peak Advisors, Inc | 118.7K | $4.77M | −$27.1K | Added$4.64M |
| Exome Asset Management LLC | 115K | $4.63M | −$1.2M | Cut−$1.67M |
| WELLS FARGO & COMPANY/MN | 114.8K | $4.62M | −$1.19M | Cut−$2.74M |
| PLATINUM INVESTMENT MANAGEMENT LTD | 113.7K | $4.57M | −$1.18M | Cut−$1.47M |
| Cinctive Capital Management LP | 106.1K | $4.27M | −$672.7K | Added$995.6K |
| Rafferty Asset Management, LLC | 101.8K | $4.09M | −$893.6K | Cut−$251.9K |
| CenterBook Partners LP | 97K | $3.9M | −$162.8K | Added$3.11M |
| Nicholas Investment Partners, LP | 95.9K | $3.86M | −$998.7K | Cut−$3.47M |
| Trexquant Investment LP | 86.7K | $3.49M | −$521.1K | Added$952.6K |
| Ishara Investments LP | 82K | $3.3M | — | New |
| Jump Financial, LLC | 81.6K | $3.28M | −$62.4K | Added$2.98M |
| Swiss National Bank | 75.6K | $3.04M | −$787K | Cut−$787K |
| RHUMBLINE ADVISERS | 74.5K | $3M | −$692.4K | Cut−$369.6K |
| HighVista Strategies LLC | 69.2K | $2.79M | — | New |
| RAYMOND JAMES FINANCIAL INC | 65.2K | $2.62M | −$675.3K | Cut−$662.3K |
| Soviero Asset Management, LP | 65K | $2.61M | −$676.7K | Cut−$1.69M |
| BOOTHBAY FUND MANAGEMENT, LLC | 64.7K | $2.6M | −$136.1K | Added$1.94M |
| Capricorn Fund Managers Ltd | 64.6K | $2.6M | — | New |
| WELLINGTON MANAGEMENT GROUP LLP | 59.9K | $2.41M | −$221K | Added$1.33M |
| JPMORGAN CHASE & CO | 63.1K | $2.4M | −$791.5K | Cut−$841.7K |
| Invesco Ltd. | 58.7K | $2.36M | −$611.2K | Cut−$2.19M |
| ALPS ADVISORS INC | 58.1K | $2.34M | −$545.4K | Cut−$316.3K |
| EASTERN BANK | 56K | $2.25M | −$583.5K | Cut−$583.5K |
| Man Group plc | 53.2K | $2.14M | −$336.9K | Added$502.5K |
| Russell Investments Group, Ltd. | 51.2K | $2.06M | −$532.6K | Cut−$4.27M |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 49.7K | $2M | −$393.8K | Added$85.2K |
| Headlands Technologies LLC | 49.2K | $1.98M | −$445.8K | Cut−$188.4K |
| XTX Topco Ltd | 48.6K | $1.96M | −$104.4K | Added$1.45M |
| PROFUND ADVISORS LLC | 45.5K | $1.83M | −$333.4K | Added$207.6K |
| Birchview Capital, LP | 44K | $1.77M | −$458K | Cut−$458K |
| E. Ohman J:or Asset Management AB | 43K | $1.73M | −$411.2K | Cut−$270.8K |
| Hennion & Walsh Asset Management, Inc. | 42.9K | $1.72M | −$441.1K | Cut−$420.8K |
| LMR Partners LLP | 40.8K | $1.64M | — | New |
| Lighthouse Investment Partners, LLC | 40K | $1.61M | — | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 36.2K | $1.44M | −$336.3K | Cut−$119.9K |
| FIFTH THIRD BANCORP | 35.5K | $1.43M | — | New |
| Legal & General Group Plc | 34K | $1.37M | −$353.5K | Cut−$984.9K |
| MetLife Investment Management, LLC | 33.8K | $1.36M | −$317.1K | Cut−$182.7K |
| KVP Capital Advisors, LP | 32.7K | $1.32M | −$340.4K | Cut−$340.4K |
| NEW YORK STATE COMMON RETIREMENT FUND | 31.2K | $1.26M | −$325.3K | Cut−$668.3K |
| PRELUDE CAPITAL MANAGEMENT, LLC | 29.9K | $1.2M | −$311.5K | Cut−$318.9K |
| SECTORAL ASSET MANAGEMENT INC | 25.6K | $1.08M | −$210.4K | Cut−$781.8K |
| VANGUARD ASSET MANAGEMENT, Ltd | 26.3K | $1.06M | — | Held |
| Knott David M Jr | 26K | $1.05M | −$270.7K | Cut−$270.7K |
| Quantinno Capital Management LP | 25.6K | $1.03M | −$154.6K | Added$279.2K |
| Vanguard Global Advisers, LLC | 25.2K | $1.02M | — | Held |
| SBI Okasan Asset Management Co.Ltd. | 26.2K | $998.2K | −$370.7K | Cut−$579.7K |
| GC Wealth Management RIA, LLC | 24K | $965.5K | −$249.7K | Cut−$249.1K |
| Walleye Capital LLC | 23.2K | $931.6K | −$155.4K | Added$175.7K |
| AMI ASSET MANAGEMENT CORP | 22K | $883.1K | −$228.5K | Cut−$561.3K |
| TWINBEECH CAPITAL LP | 21.7K | $873K | −$197.1K | Cut−$85.6K |
| JANE STREET GROUP, LLC | 21.1K | $850.9K | — | New |
| VICTORY CAPITAL MANAGEMENT INC | 21K | $843.6K | −$153.7K | Added$95.8K |
| PRUDENTIAL FINANCIAL INC | 20.7K | $832.4K | — | New |
| Odyssean, LLC | 20.5K | $825.1K | −$78K | Added$445.5K |
| SummitTX Capital, L.P. | 20.2K | $814.4K | — | New |
| ROYAL BANK OF CANADA | 20K | $804K | −$71.3K | Added$456K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 19.9K | $800.5K | −$193.9K | Cut−$142.7K |
| STATE OF WISCONSIN INVESTMENT BOARD | 19.3K | $775.8K | −$200.7K | Cut−$363K |
| JANUS HENDERSON GROUP PLC | 17.7K | $710.3K | −$144.8K | Added$4.97K |
| INTECH INVESTMENT MANAGEMENT LLC | 17.1K | $686.4K | −$177.6K | Cut−$216.9K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 16.9K | $681.1K | −$176.3K | Cut−$753.1K |
| Police & Firemen's Retirement System of New Jersey | 16.8K | $674.5K | −$156.4K | Cut−$86.5K |
| Legato Capital Management LLC | 16.2K | $651.4K | −$168.6K | Cut−$599.6K |
| ADAR1 Capital Management, LLC | 16K | $645K | −$153.4K | Cut−$101.1K |
| Icahn Capital | 16K | $644K | −$82.3K | Added$243.6K |
| Quinn Opportunity Partners LLC | 16K | $643.7K | −$166.6K | Cut−$318.5K |
| Squarepoint Ops LLC | 15.7K | $631K | — | New |
| Corient Private Wealth LLC | 15.3K | $613.8K | — | New |
| Perigon Wealth Management, LLC | 15K | $602.5K | −$149.9K | Cut−$126.5K |
| AMERIPRISE FINANCIAL INC | 15K | $602.4K | −$155.9K | Cut−$164.4K |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 14.4K | $579.1K | −$123.9K | Cut−$23.5K |
| Calamos Advisors LLC | 13.1K | $528.9K | — | New |
| State of New Jersey Common Pension Fund D | 13.1K | $526.5K | −$136.1K | Cut−$135.4K |
| J. Safra Sarasin Holding AG | 13K | $524.3K | −$135.7K | Cut−$2.13M |
| SEI INVESTMENTS CO | 13K | $523K | −$63.2K | Added$215.7K |
| E Fund Management Co., Ltd. | 12.8K | $514.7K | — | Held |
| China Universal Asset Management Co., Ltd. | 12.7K | $509.4K | −$108.4K | Cut−$18.1K |
| Neo Ivy Capital Management | 12.2K | $489.5K | −$126.7K | Cut−$799.4K |
| ProShare Advisors LLC | 12.2K | $489K | −$126.5K | Cut−$166.2K |
| Y-Intercept (Hong Kong) Ltd | 11.7K | $469.5K | −$121.5K | Cut−$1.02M |
| Quadrature Capital Ltd | 10.5K | $423.9K | — | New |
| ARIZONA STATE RETIREMENT SYSTEM | 10.5K | $423.1K | −$108.5K | Cut−$104.6K |
| Verdad Advisers, LP | 10.2K | $409.6K | — | New |
| Jasper Ridge Partners, L.P. | 10.2K | $408.5K | −$105.7K | Cut−$105.7K |
| PSP Research LLC | 10K | $402.3K | −$104.1K | Cut−$103.9K |
| Quarry LP | 10K | $402.3K | — | New |
| Creative Planning | 9.85K | $396.2K | −$97K | Cut−$75.8K |
| Vanguard Investments Australia, Ltd. | 9.82K | $395.1K | — | Held |
| DRW Securities, LLC | 8.79K | $353.8K | — | New |
| Allianz Asset Management GmbH | 8.7K | $350K | −$90.6K | Cut−$90.6K |
| KLP KAPITALFORVALTNING AS | 8.5K | $342K | −$88.5K | Cut−$88.5K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 8.46K | $340.2K | $9.63K | Added$313.1K |
| NEUBERGER BERMAN GROUP LLC | 8.03K | $323.1K | — | New |
| FRANKLIN RESOURCES INC | 7.85K | $315.8K | −$78.8K | Cut−$67.5K |
| Bridgefront Capital, LLC | 7.71K | $310.4K | — | New |
| Mariner, LLC | 7.63K | $307.1K | −$79.5K | Cut−$87.3K |
| MML INVESTORS SERVICES, LLC | 7.57K | $304.5K | — | New |
| Engineers Gate Manager LP | 6.44K | $259.1K | — | New |
| Magnetar Financial LLC | 6.4K | $257.4K | — | New |
| COMMONWEALTH EQUITY SERVICES, LLC | 6.26K | $251.7K | −$63.9K | Cut−$59.3K |
| STRS OHIO | 6.2K | $249.4K | — | New |
| CAPSTONE INVESTMENT ADVISORS, LLC | 5.73K | $230.5K | — | New |
| XPONANCE LLC | 5.69K | $228.9K | −$45.4K | Added$8.13K |
| D. E. Shaw & Co., Inc. | 5.5K | $221.3K | — | New |
| Virtus Investment Advisers, LLC | 5.47K | $220.2K | −$55.6K | Cut−$50.3K |
| Ameritas Investment Partners, Inc. | 5.06K | $203.6K | −$47K | Cut−$24.9K |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 4.99K | $200.7K | −$51.9K | Cut−$89.1K |
| PRICE T ROWE ASSOCIATES INC /MD/ | 4.57M | $184K | −$47.6K | Cut−$92.6K |
| Tower Research Capital LLC (TRC) | 3.88K | $156.1K | −$5.59K | Added$128.9K |
| Mirae Asset Global Investments Co., Ltd. | 3.72K | $149.7K | −$32.3K | Cut−$7.55K |
| Caitong International Asset Management Co., Ltd | 2.74K | $110.1K | −$177 | Added$109.2K |
| Rockefeller Capital Management L.P. | 1.82K | $73.4K | −$2K | Added$63.7K |
| Centiva Capital, LP | 1.59K | $64K | −$13.1K | Added$109 |
| GF FUND MANAGEMENT CO. LTD. | 1.44K | $57.8K | −$13.1K | Cut−$5.83K |
| Quantbot Technologies LP | 1.31K | $52.8K | −$13.7K | Cut−$246.4K |
| Allworth Financial LP | 1.07K | $43.2K | −$511 | Added$40.8K |
| OSAIC HOLDINGS, INC. | 1.03K | $41.6K | −$9.83K | Cut−$6.25K |
| GAMMA Investing LLC | 694 | $27.9K | −$7.22K | Cut−$7.68K |
| NISA INVESTMENT ADVISORS, LLC | 563 | $22.6K | −$5.8K | Cut−$5.56K |
| HUNTINGTON NATIONAL BANK | 515 | $20.7K | −$5.36K | Cut−$12.2K |
| Redwood Park Advisors LLC | 500 | $20.1K | −$5.21K | Cut−$5.21K |
| Kemnay Advisory Services Inc. | 499 | $20.1K | — | New |
| Bayforest Capital Ltd | 415 | $16.7K | — | New |
| Sterling Capital Management LLC | 402 | $16.2K | −$3.78K | Cut−$2.21K |
| CWM, LLC | 375 | $15.1K | $6.31K | Added$15.1K |
| Steward Partners Investment Advisory, LLC | 372 | $15K | −$3.66K | Cut−$2.86K |
| Optiver Holding B.V. | 202 | $8.13K | −$2.1K | Cut−$5.14K |
| SIMPLEX TRADING, LLC | 191 | $7.68K | — | New |
| ROTHSCHILD INVESTMENT LLC | 131 | $5.27K | −$1.04K | Added$206 |
| Smartleaf Asset Management LLC | 120 | $4.57K | −$1.35K | Cut−$699 |
| Larson Financial Group LLC | 106 | $4.26K | −$604 | Added$1.33K |
| US BANCORP \DE\ | 105 | $4.22K | −$448 | Added$2.05K |
| JONES FINANCIAL COMPANIES LLLP | 104 | $4.04K | −$1.23K | Cut−$1.23K |
| GW&K Investment Management, LLC | 89K | $3.58K | −$927 | Cut−$2.18K |
| Parallel Advisors, LLC | 64 | $2.58K | −$666 | Cut−$13.7K |
| PNC Financial Services Group, Inc. | 62 | $2.49K | −$646 | Cut−$646 |
| Sankala Group LLC | 61 | $2.38K | −$112 | Cut−$112 |
| Parkside Financial Bank & Trust | 40 | $1.61K | −$395 | Cut−$315 |
| ALGERT GLOBAL LLC | 36.3K | $1.46K | −$378 | Cut−$1.82K |
| Hughes Financial Services, LLC | 32 | $1.29K | −$21 | Added$1.19K |
| MAI Capital Management | 27 | $1.09K | — | New |
| Farther Finance Advisors, LLC | 22 | $891 | −$223 | Cut−$527 |
| Handelsbanken Fonder AB | 19.8K | $797 | −$206 | Cut−$206 |
| LRI Investments, LLC | 18 | $724 | −$188 | Cut−$188 |
| Arax Advisory Partners | 17 | $684 | −$94 | Added$228 |
| SG Americas Securities, LLC | 12.7K | $509 | −$132 | Cut−$828 |
| Advisory Services Network, LLC | 10 | $402 | — | New |
| Keating Financial Advisory Services, Inc. | 6 | $241 | — | New |
| GSA CAPITAL PARTNERS LLP | 5.69K | $229 | — | New |
| EverSource Wealth Advisors, LLC | 5 | $201 | −$11 | Added$150 |
| ACADIAN ASSET MANAGEMENT LLC | 3.96K | $159 | −$41 | Cut−$41 |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 3.72K | $150 | −$38 | Cut−$38 |
| MassMutual Private Wealth & Trust, FSB | 3 | $121 | — | New |
| Essential Partners LLC | 3 | $121 | −$20 | Added$20 |
| TWIN PEAKS WEALTH ADVISORS, LLC | 2 | $80 | — | New |
| KBC Group NV | 1.28K | $52 | −$13 | Cut−$47 |
| True Wealth Design, LLC | 1 | $41 | −$10 | Cut−$10 |
| GHP Investment Advisors, Inc. | 1 | $41 | — | New |
| SBI Securities Co., Ltd. | 1 | $40 | −$11 | Cut−$61 |
| IFP Advisors, Inc | 1 | $40 | — | New |
| HANTZ FINANCIAL SERVICES, INC. | 3 | $0 | — | New |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | $0 | — | Held |
| Covestor Ltd | 4 | $0 | $0 | Held |