| Avoro Capital Advisors LLC | 5.89M | $298.2M | — | Held |
| BlackRock, Inc. | 4.83M | $244.4M | — | Held |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 4.06M | $205.6M | — | Held |
| Vanguard | 3.57M | $180.8M | — | Held |
| Kynam Capital Management, LP | 3.43M | $173.8M | — | Held |
| Eversept Partners, LP | 3.07M | $155.6M | — | Held |
| Fidelity | 2.89M | $146.1M | — | Held |
| Deep Track Capital, LP | 2.82M | $142.9M | — | Held |
| Sofinnova Investments, Inc. | 2.79M | $141.5M | — | Held |
| State Street | 2.68M | $135.5M | — | Held |
| Integral Health Asset Management, LLC | 1.8M | $91.2M | — | Held |
| Point72 Asset Management, L.P. | 1.74M | $88M | — | Held |
| Bellevue Group AG | 1.7M | $86M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 1.44M | $73.2M | — | Held |
| Pictet Asset Management Holding SA | 1.39M | $70.5M | — | Held |
| Holocene Advisors, LP | 1.31M | $66.2M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 1.22M | $61.7M | — | Held |
| GOLDMAN SACHS GROUP INC | 1.12M | $56.8M | — | Held |
| Woodline Partners LP | 1M | $50.7M | — | Held |
| First Light Asset Management, LLC | 869.7K | $44M | — | Held |
| Tri Locum Partners LP | 805.7K | $40.8M | — | Held |
| BRAIDWELL LP | 784.7K | $39.7M | — | Held |
| Citadel | 777.5K | $39.4M | — | Held |
| AMERICAN CENTURY COMPANIES INC | 732.7K | $37.1M | — | Held |
| BANK OF AMERICA CORP /DE/ | 694.3K | $35.2M | $10.6M | Added$20.9M |
| ARMISTICE CAPITAL, LLC | 653.8K | $33.1M | — | Held |
| First Turn Management, LLC | 601.8K | $30.5M | — | Held |
| Rock Springs Capital Management LP | 568.6K | $28.8M | — | Held |
| Vestal Point Capital, LP | 550K | $27.9M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 518.9K | $26.3M | — | Held |
| MORGAN STANLEY | 499.7K | $25.3M | $5.92M | Added$17.3M |
| Elmind Capital, LP | 482.5K | $24.4M | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 474.7K | $24M | — | Held |
| NORTHERN TRUST CORP | 473.2K | $24M | — | Held |
| Candriam S.C.A. | 449.6K | $22.8M | — | Held |
| Rhenman & Partners Asset Management AB | 420K | $21.3M | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 419K | $21.2M | — | Held |
| Qube Research & Technologies Ltd | 378.1K | $19.1M | — | Held |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 371.2K | $18.8M | — | Held |
| ORBIMED ADVISORS LLC | 353.5K | $17.9M | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 351.9K | $17.8M | — | Held |
| DEUTSCHE BANK AG\ | 347.4K | $17.6M | — | Held |
| TD Asset Management Inc | 325.6K | $16.5M | — | Held |
| BARCLAYS PLC | 253.7K | $12.8M | $4.7M | Added$6.52M |
| TimesSquare Capital Management, LLC | 252.5K | $12.8M | — | Held |
| Affinity Asset Advisors, LLC | 250K | $12.7M | — | Held |
| Alphabet Inc. | 241.3K | $12.2M | — | Held |
| Nuveen, LLC | 227.1K | $11.5M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 210K | $10.6M | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 208K | $10.6M | — | Held |
| UBS Group AG | 207.3K | $10.5M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 203K | $10.3M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 199.7K | $10.1M | — | Held |
| Renaissance Technologies | 193.4K | $9.79M | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 176.7K | $8.95M | — | Held |
| CITIGROUP INC | 174.3K | $8.82M | — | Held |
| Bank of New York Mellon Corp | 169.7K | $8.6M | — | Held |
| WELLS FARGO & COMPANY/MN | 145.2K | $7.35M | — | Held |
| Nicholas Investment Partners, LP | 144.8K | $7.33M | — | Held |
| Russell Investments Group, Ltd. | 124.9K | $6.32M | — | Held |
| Exome Asset Management LLC | 124.4K | $6.3M | — | Held |
| Swedbank AB | 121.2K | $6.14M | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 120.6K | $6.11M | — | Held |
| PLATINUM INVESTMENT MANAGEMENT LTD | 119.4K | $6.05M | — | Held |
| PFM Health Sciences, LP | 107.7K | $5.45M | — | Held |
| Parkman Healthcare Partners LLC | 100.6K | $5.09M | — | Held |
| Invesco Ltd. | 89.9K | $4.55M | — | Held |
| Rafferty Asset Management, LLC | 85.8K | $4.35M | — | Held |
| Soviero Asset Management, LP | 85K | $4.3M | — | Held |
| Swiss National Bank | 75.6K | $3.83M | — | Held |
| ExodusPoint Capital Management, LP | 72.7K | $3.68M | — | Held |
| RHUMBLINE ADVISERS | 66.5K | $3.37M | — | Held |
| RAYMOND JAMES FINANCIAL INC | 64.9K | $3.29M | — | Held |
| Cinctive Capital Management LP | 64.6K | $3.27M | — | Held |
| JPMORGAN CHASE & CO | 64.1K | $3.25M | — | Held |
| EASTERN BANK | 56K | $2.84M | — | Held |
| Balyasny Asset Management L.P. | 54.3K | $2.75M | — | Held |
| ALPS ADVISORS INC | 52.4K | $2.65M | — | Held |
| J. Safra Sarasin Holding AG | 52.3K | $2.65M | — | Held |
| Trexquant Investment LP | 50.1K | $2.53M | — | Held |
| Legal & General Group Plc | 46.4K | $2.35M | — | Held |
| Birchview Capital, LP | 44K | $2.23M | — | Held |
| Headlands Technologies LLC | 42.8K | $2.17M | — | Held |
| Hennion & Walsh Asset Management, Inc. | 42.4K | $2.15M | — | Held |
| E. Ohman J:or Asset Management AB | 39.5K | $2M | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 38K | $1.93M | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 37.8K | $1.92M | — | Held |
| SECTORAL ASSET MANAGEMENT INC | 36.9K | $1.87M | — | Held |
| KVP Capital Advisors, LP | 32.7K | $1.66M | — | Held |
| Schonfeld Strategic Advisors LLC | 32.4K | $1.64M | — | Held |
| Man Group plc | 32.4K | $1.64M | — | Held |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 31.8K | $1.63M | — | Held |
| PROFUND ADVISORS LLC | 32K | $1.62M | — | Held |
| SBI Okasan Asset Management Co.Ltd. | 30.2K | $1.58M | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 30.8K | $1.56M | — | Held |
| DARK FOREST CAPITAL MANAGEMENT LP | 30.7K | $1.55M | — | Held |
| MetLife Investment Management, LLC | 30.5K | $1.54M | — | Held |
| PRELUDE CAPITAL MANAGEMENT, LLC | 30.1K | $1.52M | — | Held |
| Y-Intercept (Hong Kong) Ltd | 29.4K | $1.49M | — | Held |
| AMI ASSET MANAGEMENT CORP | 28.5K | $1.44M | — | Held |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 28.3K | $1.43M | — | Held |
| COMERICA BANK | 27.7K | $1.4M | — | Held |
| Knott David M Jr | 26K | $1.32M | — | Held |
| Neo Ivy Capital Management | 25.5K | $1.29M | — | Held |
| BURKEHILL GLOBAL MANAGEMENT, LP | 25K | $1.27M | — | Held |
| Legato Capital Management LLC | 24.7K | $1.25M | — | Held |
| GC Wealth Management RIA, LLC | 24K | $1.21M | — | Held |
| Monashee Investment Management LLC | 22.9K | $1.16M | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 22.5K | $1.14M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 21.2K | $1.08M | — | Held |
| Laurion Capital Management LP | 20K | $1.01M | — | Held |
| Quinn Opportunity Partners LLC | 19K | $962.2K | — | Held |
| TWINBEECH CAPITAL LP | 18.9K | $958.6K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18.6K | $943.1K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 17.8K | $903.3K | — | Held |
| Optimize Financial Inc | 17.8K | $901.4K | — | Held |
| FOX RUN MANAGEMENT, L.L.C. | 17K | $862.6K | — | Held |
| CenterBook Partners LP | 15.6K | $792K | — | Held |
| AMERIPRISE FINANCIAL INC | 15.1K | $766.7K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 15K | $761K | — | Held |
| Walleye Capital LLC | 14.9K | $755.9K | — | Held |
| Quantinno Capital Management LP | 14.9K | $752.3K | — | Held |
| VICTORY CAPITAL MANAGEMENT INC | 14.8K | $747.8K | — | Held |
| ADAR1 Capital Management, LLC | 14.7K | $746.1K | — | Held |
| Perigon Wealth Management, LLC | 14.4K | $729K | — | Held |
| JANUS HENDERSON GROUP PLC | 13.9K | $705.3K | — | Held |
| BOOTHBAY FUND MANAGEMENT, LLC | 13.1K | $661.9K | — | Held |
| State of New Jersey Common Pension Fund D | 13.1K | $661.9K | — | Held |
| ProShare Advisors LLC | 12.9K | $655.2K | — | Held |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 11.9K | $602.6K | — | Held |
| Brevan Howard Capital Management LP | 11.2K | $568K | — | Held |
| ARIZONA STATE RETIREMENT SYSTEM | 10.4K | $527.7K | — | Held |
| China Universal Asset Management Co., Ltd. | 10.4K | $527.5K | — | Held |
| Jasper Ridge Partners, L.P. | 10.2K | $514.2K | — | Held |
| XTX Topco Ltd | 10K | $507.7K | — | Held |
| PSP Research LLC | 10K | $506.2K | — | Held |
| Creative Planning | 9.32K | $472K | — | Held |
| Allianz Asset Management GmbH | 8.7K | $440.6K | — | Held |
| KLP KAPITALFORVALTNING AS | 8.5K | $430.4K | — | Held |
| Icahn Capital | 7.91K | $400.4K | — | Held |
| Mariner, LLC | 7.79K | $394.4K | — | Held |
| FRANKLIN RESOURCES INC | 7.57K | $383.4K | — | Held |
| Odyssean, LLC | 7.5K | $379.6K | — | Held |
| Jain Global LLC | 7.13K | $361.2K | — | Held |
| ROYAL BANK OF CANADA | 6.88K | $348K | — | Held |
| COMMONWEALTH EQUITY SERVICES, LLC | 6.14K | $311K | — | Held |
| SEI INVESTMENTS CO | 6.07K | $307.3K | — | Held |
| Jump Financial, LLC | 5.99K | $303.5K | — | Held |
| Quantbot Technologies LP | 5.91K | $299.2K | — | Held |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 5.72K | $289.8K | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 5.46M | $276.6K | — | Held |
| Virtus Investment Advisers, LLC | 5.34K | $270.5K | — | Held |
| Berkshire Money Management, Inc. | 5K | $253.2K | — | Held |
| Fiduciary Trust Co | 4.9K | $248.2K | — | Held |
| Voleon Capital Management LP | 4.85K | $245.5K | — | Held |
| Ameritas Investment Partners, Inc. | 4.51K | $228.5K | — | Held |
| XPONANCE LLC | 4.36K | $220.7K | — | Held |
| Argentarii, LLC | 4.33K | $219.3K | — | Held |
| Scientech Research LLC | 4.29K | $217K | — | Held |
| FORA Capital, LLC | 4.07K | $206.3K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 3.11K | $157.3K | — | Held |
| Ensign Peak Advisors, Inc | 2.6K | $131.7K | — | Held |
| Sandia Investment Management LP | 2.5K | $126.6K | — | Held |
| AlphaQuest LLC | 1.6K | $81.3K | — | Held |
| Aster Capital Management (DIFC) Ltd | 1.41K | $71.2K | — | Held |
| Centiva Capital, LP | 1.26K | $63.9K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 1.26K | $63.6K | — | Held |
| OSAIC HOLDINGS, INC. | 944 | $47.8K | — | Held |
| GAMMA Investing LLC | 703 | $35.6K | — | Held |
| HUNTINGTON NATIONAL BANK | 650 | $32.9K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 557 | $28.2K | — | Held |
| Tower Research Capital LLC (TRC) | 537 | $27.2K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 912 | $27.1K | — | Held |
| Redwood Park Advisors LLC | 500 | $25.3K | — | Held |
| Garner Asset Management Corp | 400 | $20.3K | — | Held |
| Sterling Capital Management LLC | 363 | $18.4K | — | Held |
| Steward Partners Investment Advisory, LLC | 352 | $17.8K | — | Held |
| Parallel Advisors, LLC | 322 | $16.3K | — | Held |
| Optiver Holding B.V. | 262 | $13.3K | — | Held |
| Rockefeller Capital Management L.P. | 192 | $9.72K | — | Held |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 154.6K | $7.83K | — | Held |
| GW&K Investment Management, LLC | 113.8K | $5.76K | — | Held |
| Smartleaf Asset Management LLC | 103 | $5.27K | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 104 | $5.27K | — | Held |
| ROTHSCHILD INVESTMENT LLC | 100 | $5.06K | — | Held |
| Federation des caisses Desjardins du Quebec | 80 | $4.05K | — | Held |
| ALGERT GLOBAL LLC | 64.9K | $3.29K | — | Held |
| PNC Financial Services Group, Inc. | 62 | $3.14K | — | Held |
| Larson Financial Group LLC | 58 | $2.94K | — | Held |
| Sankala Group LLC | 61 | $2.49K | — | Held |
| Allworth Financial LP | 49 | $2.48K | $733 | Added$1.49K |
| US BANCORP \DE\ | 43 | $2.18K | — | Held |
| Parkside Financial Bank & Trust | 38 | $1.93K | — | Held |
| Farther Finance Advisors, LLC | 28 | $1.42K | — | Held |
| SG Americas Securities, LLC | 26.4K | $1.34K | — | Held |
| ZIONS BANCORPORATION, NATIONAL ASSOCIATION /UT/ | 21 | $1.06K | — | Held |
| Handelsbanken Fonder AB | 19.8K | $1K | — | Held |
| LRI Investments, LLC | 18 | $912 | — | Held |
| Caitong International Asset Management Co., Ltd | 17 | $861 | — | Held |
| Arax Advisory Partners | 9 | $456 | — | Held |
| Bare Financial Services, Inc | 9 | $456 | — | Held |
| Virtu Financial LLC | 5.87K | $297 | — | Held |
| ACADIAN ASSET MANAGEMENT LLC | 3.96K | $200 | — | Held |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 3.72K | $188 | — | Held |
| Essential Partners LLC | 2 | $101 | $43 | Added$43 |
| SBI Securities Co., Ltd. | 2 | $101 | — | Held |
| Hughes Financial Services, LLC | 2 | $101 | — | Held |
| KBC Group NV | 1.95K | $99 | $42 | Added$42 |
| AMALGAMATED BANK | 1.75K | $88 | — | Held |
| True Wealth Design, LLC | 1 | $51 | — | Held |
| EverSource Wealth Advisors, LLC | 1 | $51 | — | Held |
| Daiwa Securities Group Inc. | 183 | $9 | — | Held |
| CWM, LLC | 157 | $8 | — | Held |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | $0 | — | Held |
| Covestor Ltd | 4 | $0 | — | Held |