| RA CAPITAL MANAGEMENT, L.P. | 10.9M | $126.5M | — | Held |
| ORBIMED ADVISORS LLC | 8.29M | $96.6M | — | Held |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 7.5M | $87.4M | — | Held |
| Rubric Capital Management LP | 6.2M | $72.2M | — | Held |
| BlackRock, Inc. | 5.09M | $59.2M | — | Held |
| SR One Capital Management, LP | 4.01M | $46.8M | — | Held |
| Aberdeen Group plc | 3.56M | $41.4M | — | Held |
| Vanguard | 3.51M | $40.9M | — | Held |
| State Street | 3.22M | $37.6M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 3.17M | $36.9M | — | Held |
| FRANKLIN RESOURCES INC | 2.54M | $29.6M | — | Held |
| UBS Group AG | 2.21M | $25.8M | — | Held |
| Tyro Capital Management LLC | 1.99M | $23.2M | — | Held |
| Citadel | 1.95M | $22.8M | — | Held |
| Casdin Capital, LLC | 1.6M | $18.6M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 1.55M | $18.1M | — | Held |
| Southpoint Capital Advisors LP | 1.5M | $17.5M | — | Held |
| BAMCO INC /NY/ | 1.27M | $14.8M | — | Held |
| GOLDMAN SACHS GROUP INC | 812K | $9.46M | — | Held |
| FIL Ltd | 810.1K | $9.44M | — | Held |
| LEVIN CAPITAL STRATEGIES, L.P. | 747.5K | $8.71M | — | Held |
| Nextech Invest, Ltd. | 660.7K | $7.7M | — | Held |
| BANK OF MONTREAL /CAN/ | 643.4K | $7.5M | — | Held |
| CenterBook Partners LP | 568.4K | $6.62M | — | Held |
| RAYMOND JAMES FINANCIAL INC | 566.1K | $6.59M | — | Held |
| GENERAL AMERICAN INVESTORS CO INC | 560K | $6.52M | — | Held |
| Third Point | 556.2K | $6.48M | — | Held |
| MORGAN STANLEY | 552.4K | $6.44M | $883.8K | Cut−$604.1K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 550.9K | $6.42M | — | Held |
| NORTHERN TRUST CORP | 521K | $6.07M | — | Held |
| BANK OF AMERICA CORP /DE/ | 482.1K | $5.62M | $435.2K | Added$2.88M |
| AMERICAN CENTURY COMPANIES INC | 455.8K | $5.31M | — | Held |
| Alyeska Investment Group, L.P. | 418.9K | $4.88M | — | Held |
| JPMORGAN CHASE & CO | 417.1K | $4.86M | — | Held |
| Fidelity | 399K | $4.65M | — | Held |
| Lisanti Capital Growth, LLC | 396.5K | $4.62M | — | Held |
| ADAR1 Capital Management, LLC | 369.6K | $4.31M | — | Held |
| Empire Life Investments Inc. | 352.6K | $4.11M | — | Held |
| INVESTMENT MANAGEMENT ASSOCIATES INC /ADV | 311.5K | $3.63M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 304.4K | $3.55M | — | Held |
| Creek Drive Management Group LLC | 295.9K | $3.45M | — | Held |
| Eversept Partners, LP | 251.6K | $2.93M | — | Held |
| Steward Partners Investment Advisory, LLC | 216.3K | $2.52M | — | Held |
| ROYCE & ASSOCIATES LP | 207.1K | $2.41M | — | Held |
| FAS Wealth Partners, Inc. | 202.4K | $2.36M | — | Held |
| BOOTHBAY FUND MANAGEMENT, LLC | 201.5K | $2.35M | — | Held |
| BARCLAYS PLC | 196.4K | $2.29M | $314.2K | Cut−$9.21K |
| DAFNA Capital Management LLC | 190.1K | $2.21M | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 176.1K | $2.05M | — | Held |
| WEXFORD CAPITAL LP | 165.3K | $1.93M | — | Held |
| Bank of New York Mellon Corp | 163K | $1.9M | — | Held |
| Quinn Opportunity Partners LLC | 155K | $1.81M | — | Held |
| Woodline Partners LP | 150.9K | $1.76M | — | Held |
| Trexquant Investment LP | 150.1K | $1.75M | — | Held |
| Nuveen, LLC | 149.6K | $1.74M | — | Held |
| Knights of Columbus Asset Advisors LLC | 130.7K | $1.52M | — | Held |
| Rafferty Asset Management, LLC | 115.6K | $1.35M | — | Held |
| PRINCIPAL FINANCIAL GROUP INC | 112.8K | $1.31M | — | Held |
| Legato Capital Management LLC | 109.1K | $1.27M | — | Held |
| Swiss National Bank | 107.2K | $1.25M | — | Held |
| VALLEY FORGE INVESTMENT CONSULTANTS INC ADV | 83.2K | $969.6K | — | Held |
| ALPS ADVISORS INC | 81.2K | $945.6K | — | Held |
| MARSHALL WACE, LLP | 79.2K | $922.8K | — | Held |
| AssuredPartners Investment Advisors, LLC | 75.8K | $882.8K | — | Held |
| SEI INVESTMENTS CO | 74.8K | $871.5K | — | Held |
| WELLS FARGO & COMPANY/MN | 74.3K | $865.1K | — | Held |
| RHUMBLINE ADVISERS | 73.3K | $853.9K | — | Held |
| ALLIANCEBERNSTEIN L.P. | 60.1K | $700.4K | — | Held |
| Legal & General Group Plc | 58.4K | $680K | — | Held |
| Matisse Capital | 55.6K | $647.3K | — | Held |
| AMERICAN ASSETS INC | 55K | $640.8K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 54.1K | $630.2K | — | Held |
| Coastal Bridge Advisors, LLC | 53.8K | $627.1K | — | Held |
| Quantinno Capital Management LP | 53.1K | $618.8K | — | Held |
| Permanent Capital Management, LP | 52.3K | $609.4K | — | Held |
| SCHULHOFF & CO INC | 51.1K | $595.9K | — | Held |
| DEUTSCHE BANK AG\ | 48.7K | $567.7K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 65.7K | $566.7K | — | Held |
| PROFUND ADVISORS LLC | 42.8K | $498.7K | — | Held |
| FOX RUN MANAGEMENT, L.L.C. | 38.6K | $449.5K | — | Held |
| Invesco Ltd. | 37.2K | $433.7K | — | Held |
| XTX Topco Ltd | 37.2K | $433.4K | — | Held |
| Aquatic Capital Management LLC | 36K | $419.8K | — | Held |
| MetLife Investment Management, LLC | 34.3K | $400K | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 34.1K | $397.6K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 34.1K | $397.2K | — | Held |
| DIKER MANAGEMENT LLC | 33.5K | $390.4K | — | Held |
| AlphaQuest LLC | 33K | $384.1K | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 32.1K | $373.5K | — | Held |
| Private Advisor Group, LLC | 31.5K | $366.5K | — | Held |
| Cresset Asset Management, LLC | 30.2K | $351.3K | $48.2K | Added$48.2K |
| SECTORAL ASSET MANAGEMENT INC | 29.8K | $347.2K | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 29.6K | $344.8K | — | Held |
| Freestone Grove Partners LP | 28K | $326.2K | — | Held |
| HighTower Advisors, LLC | 26.5K | $309.1K | — | Held |
| D. E. Shaw & Co., Inc. | 26.5K | $309K | — | Held |
| Belpointe Asset Management LLC | 25.5K | $296.7K | — | Held |
| Creative Planning | 25.3K | $295.1K | — | Held |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | 25K | $291.3K | — | Held |
| LETKO, BROSSEAU & ASSOCIATES INC | 24.7K | $287.8K | — | Held |
| Wealthspire Advisors, LLC | 23.6K | $275.5K | — | Held |
| LPL Financial LLC | 22.9K | $267K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 22.6K | $263.6K | — | Held |
| VARCOV Co. | 22.3K | $259.8K | — | Held |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 21.6K | $251.8K | — | Held |
| JANUS HENDERSON GROUP PLC | 21.6K | $251.7K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 20.6K | $240.2K | — | Held |
| Everstar Asset Management, LLC | 20K | $233K | — | Held |
| CITIGROUP INC | 18.6K | $216.3K | — | Held |
| OPPENHEIMER & CO INC | 17.9K | $208K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 17.7K | $206.3K | — | Held |
| China Universal Asset Management Co., Ltd. | 16.1K | $187.6K | — | Held |
| ARIZONA STATE RETIREMENT SYSTEM | 15.4K | $179.1K | — | Held |
| Cetera Investment Advisers | 15.3K | $178.7K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 15.1K | $176.5K | — | Held |
| ProShare Advisors LLC | 15.1K | $176.4K | — | Held |
| LAZARD ASSET MANAGEMENT LLC | 14.3K | $167.1K | — | Held |
| SHERBROOKE PARK ADVISERS LLC | 13.1K | $153.1K | — | Held |
| Tannin Capital LLC | 13.1K | $152.2K | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 12.1K | $141.4K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 11.7K | $135.9K | — | Held |
| KLP KAPITALFORVALTNING AS | 11.6K | $135.1K | — | Held |
| BLAIR WILLIAM & CO/IL | 11.6K | $135.1K | — | Held |
| Pictet Asset Management Holding SA | 10.4K | $120.7K | — | Held |
| K2 PRINCIPAL FUND, L.P. | 10.2K | $118.8K | — | Held |
| Wealth Architects, LLC | 10K | $116.5K | — | Held |
| GROUP ONE TRADING LLC | 9.52K | $110.9K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 6.41K | $74.6K | — | Held |
| Russell Investments Group, Ltd. | 5.8K | $67.6K | — | Held |
| OSTERWEIS CAPITAL MANAGEMENT INC | 5.61K | $65.4K | — | Held |
| Ameritas Investment Partners, Inc. | 4.89K | $56.9K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 4.8K | $56K | — | Held |
| ROYAL BANK OF CANADA | 4.68K | $54K | — | Held |
| OSAIC HOLDINGS, INC. | 3.63K | $42.2K | — | Held |
| Kestra Advisory Services, LLC | 3.47K | $40.4K | — | Held |
| SIGNATUREFD, LLC | 2.81K | $32.8K | — | Held |
| Torren Management, LLC | 2.76K | $32.2K | — | Held |
| Versant Capital Management, Inc | 2.57K | $30K | — | Held |
| Bernard Wealth Management Corp. | 2.52K | $29.4K | — | Held |
| TD Waterhouse Canada Inc. | 2.16K | $25.2K | — | Held |
| CAZ INVESTMENTS LP | 2K | $23.3K | — | Held |
| Smartleaf Asset Management LLC | 1.95K | $22.7K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 1.94K | $22.6K | — | Held |
| Rockefeller Capital Management L.P. | 1.89K | $22.1K | — | Held |
| US BANCORP \DE\ | 1.48K | $17.2K | — | Held |
| Janney Montgomery Scott LLC | 1.29M | $15K | — | Held |
| Farther Finance Advisors, LLC | 1.14K | $13.3K | — | Held |
| Tower Research Capital LLC (TRC) | 1.05K | $12.2K | — | Held |
| Heritage Wealth Advisors | 1K | $11.7K | — | Held |
| EASTERN BANK | 750 | $8.74K | — | Held |
| SBI Securities Co., Ltd. | 749 | $8.73K | — | Held |
| Allworth Financial LP | 743 | $8.66K | $1.19K | Added$656 |
| Golden State Wealth Management, LLC | 484 | $5.64K | — | Held |
| Sterling Capital Management LLC | 402 | $4.68K | — | Held |
| BROWN, LISLE/CUMMINGS, INC. | 400 | $4.66K | — | Held |
| Spire Wealth Management | 400 | $4.66K | — | Held |
| Arax Advisory Partners | 369 | $4.3K | — | Held |
| Hilton Head Capital Partners, LLC | 365 | $4.25K | — | Held |
| QUADRANT CAPITAL GROUP LLC | 347 | $4.04K | — | Held |
| Optiver Holding B.V. | 260 | $3.03K | — | Held |
| Quarry LP | 250 | $2.91K | — | Held |
| COMERICA BANK | 217 | $2.53K | — | Held |
| Key Financial Inc | 200 | $2.33K | — | Held |
| Tidemark, LLC | 169 | $1.97K | — | Held |
| Aster Capital Management (DIFC) Ltd | 153 | $1.78K | — | Held |
| GAMMA Investing LLC | 108 | $1.26K | — | Held |
| Tripletail Wealth Management, LLC | 100 | $1.17K | — | Held |
| SIT INVESTMENT ASSOCIATES INC | 92.9K | $1.08K | — | Held |
| Cambridge Investment Research Advisors, Inc. | 87.2K | $1.01K | — | Held |
| Larson Financial Group LLC | 83 | $967 | — | Held |
| SG Americas Securities, LLC | 76.2K | $888 | — | Held |
| HRT FINANCIAL LP | 68.6K | $799 | — | Held |
| PNC Financial Services Group, Inc. | 36 | $419 | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 33.8K | $394 | — | Held |
| Strategic Wealth Partners, Ltd. | 20 | $233 | — | Held |
| ROTHSCHILD INVESTMENT LLC | 16 | $186 | — | Held |
| FOSTER & MOTLEY INC | 14.8K | $172 | — | Held |
| AMICA MUTUAL INSURANCE CO | 14.3K | $167 | — | Held |
| Cygnus Capital Advisors, LLC | 10.6K | $123 | — | Held |
| CX Institutional | 8.99K | $105 | — | Held |
| EverSource Wealth Advisors, LLC | 9 | $105 | — | Held |
| Essential Partners LLC | 4 | $47 | — | New |
| AMALGAMATED BANK | 1.85K | $22 | — | Held |
| Capital Analysts, LLC | 1.3K | $15 | — | Held |
| NBC SECURITIES, INC. | 1 | $11 | — | Held |
| Avion Wealth | 500 | $5 | — | Held |
| Daiwa Securities Group Inc. | 367 | $4 | — | Held |
| BESSEMER GROUP INC | 235 | $3 | — | Held |
| CWM, LLC | 62 | $1 | — | Held |
| Covestor Ltd | 7 | $0 | — | Held |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | $0 | — | Held |