| Fidelity | 24.6M | $821.8M | — | Held |
| BlackRock, Inc. | 13M | $460.9M | — | Held |
| Vanguard | 11.5M | $409M | — | Held |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 9.04M | $321.2M | — | Held |
| Fairmount Funds Management LLC | 9M | $319.8M | — | Held |
| RTW INVESTMENTS, LP | 7.59M | $269.7M | — | Held |
| Kynam Capital Management, LP | 6.17M | $219M | — | Held |
| TCG Crossover Management, LLC | 5.87M | $208.4M | — | Held |
| State Street | 4.94M | $175.5M | — | Held |
| JANUS HENDERSON GROUP PLC | 4.54M | $161.1M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 3.51M | $124.9M | — | Held |
| D. E. Shaw & Co., Inc. | 21.2M | $102M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 2.71M | $96.3M | — | Held |
| Vivo Capital, LLC | 2.4M | $85.2M | — | Held |
| Octagon Capital Advisors LP | 2.35M | $83.5M | — | Held |
| Commodore Capital LP | 2.2M | $78M | — | Held |
| VR ADVISER, LLC | 2M | $71M | — | Held |
| Sofinnova Investments, Inc. | 1.97M | $70.1M | — | Held |
| GOLDMAN SACHS GROUP INC | 1.71M | $60.6M | — | Held |
| MARSHALL WACE, LLP | 1.66M | $59M | — | Held |
| Siren, L.L.C. | 1.63M | $57.9M | — | Held |
| Balyasny Asset Management L.P. | 6.94M | $57.6M | — | Held |
| EMERALD ADVISERS, LLC | 1.58M | $56.2M | — | Held |
| Linden Advisors LP | 44.1M | $51.7M | — | Held |
| Citadel | 1.44M | $51.1M | — | Held |
| Redmile Group, LLC | 1.44M | $51.1M | — | Held |
| Candriam S.C.A. | 1.3M | $46.1M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.28M | $45.5M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 3.21M | $45.3M | — | Held |
| SILVERARC CAPITAL MANAGEMENT, LLC | 1.25M | $44.2M | — | Held |
| Saturn V Capital Management LP | 1.22M | $43.2M | — | Held |
| NORTHERN TRUST CORP | 1.2M | $42.6M | — | Held |
| BANK OF AMERICA CORP /DE/ | 1.19M | $42.3M | $25.2M | Added$10.2M |
| Holocene Advisors, LP | 1.18M | $41.8M | — | Held |
| Elmind Capital, LP | 1.17M | $41.6M | — | Held |
| FRED ALGER MANAGEMENT, LLC | 1.1M | $39.1M | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 28.1M | $37.7M | — | Held |
| EMERALD MUTUAL FUND ADVISERS TRUST | 1.04M | $36.9M | — | Held |
| Nuveen, LLC | 932.6K | $33.1M | — | Held |
| AMERICAN CENTURY COMPANIES INC | 892.9K | $31.7M | — | Held |
| Rock Springs Capital Management LP | 849K | $30.2M | — | Held |
| Point72 Asset Management, L.P. | 827.5K | $29.4M | — | Held |
| First Turn Management, LLC | 824.3K | $29.3M | — | Held |
| Woodline Partners LP | 818.8K | $29.1M | — | Held |
| Squadron Capital Management LLC | 780K | $27.7M | — | Held |
| MORGAN STANLEY | 726.8K | $25.8M | $15.4M | Added$7.32M |
| Renaissance Technologies | 689.1K | $24.5M | — | Held |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 669K | $23.8M | — | Held |
| SONA ASSET MANAGEMENT (US) LLC | 16.1M | $22.5M | — | Held |
| WOLVERINE ASSET MANAGEMENT LLC | 18M | $21.1M | — | Held |
| Invesco Ltd. | 585.8K | $20.8M | — | Held |
| Defilade Capital Management, L.P. | 568.6K | $20.2M | — | Held |
| Atika Capital Management LLC | 506K | $18M | — | Held |
| Alyeska Investment Group, L.P. | 493.9K | $17.5M | — | Held |
| Deep Track Capital, LP | 453.1K | $16.1M | — | Held |
| J. Goldman & Co LP | 439.3K | $15.6M | — | Held |
| Calamos Advisors LLC | 13.2M | $15.5M | — | Held |
| FEDERATED HERMES, INC. | 426.8K | $15.2M | — | Held |
| Ensign Peak Advisors, Inc | 421.5K | $15M | — | Held |
| ORBIMED ADVISORS LLC | 1.37M | $14.4M | — | Held |
| AMERIPRISE FINANCIAL INC | 6.69M | $14.3M | — | Held |
| JPMORGAN CHASE & CO | 400.9K | $14.2M | — | Held |
| Russell Investments Group, Ltd. | 385.5K | $13.7M | — | Held |
| Affinity Asset Advisors, LLC | 1.35M | $13.6M | — | Held |
| SPHERA FUNDS MANAGEMENT LTD. | 378.5K | $13.4M | — | Held |
| Bank of New York Mellon Corp | 376.3K | $13.4M | — | Held |
| RAYMOND JAMES FINANCIAL INC | 375.9K | $13.4M | — | Held |
| Assenagon Asset Management S.A. | 375.6K | $13.3M | — | Held |
| SUPERSTRING CAPITAL MANAGEMENT LP | 366.2K | $13M | — | Held |
| KENNEDY CAPITAL MANAGEMENT LLC | 352.4K | $12.5M | — | Held |
| Hennion & Walsh Asset Management, Inc. | 338.1K | $12M | — | Held |
| HighVista Strategies LLC | 336.7K | $12M | — | Held |
| BURKEHILL GLOBAL MANAGEMENT, LP | 325K | $11.5M | — | Held |
| BARCLAYS PLC | 321.6K | $11.4M | $6.81M | Added$6.26M |
| Patient Square Capital LP | 317.4K | $11.3M | — | Held |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 305.9K | $10.9M | — | Held |
| Exome Asset Management LLC | 305.6K | $10.9M | — | Held |
| Man Group plc | 292.1K | $10.4M | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 283.5K | $10.1M | — | Held |
| Jump Financial, LLC | 8.12M | $10.1M | — | Held |
| Qube Research & Technologies Ltd | 276.7K | $9.83M | — | Held |
| UBS Group AG | 264K | $9.38M | — | Held |
| SummitTX Capital, L.P. | 257.2K | $9.13M | — | Held |
| OAKTREE CAPITAL MANAGEMENT LP | 7.65M | $8.99M | — | Held |
| Evergreen Quality Fund GP, Ltd. | 250K | $8.88M | — | Held |
| Nantahala Capital Management, LLC | 250K | $8.88M | — | Held |
| Polar Asset Management Partners Inc. | 7.5M | $8.79M | — | New |
| F/m Investments LLC | 235.8K | $8.38M | — | Held |
| Susquehanna Portfolio Strategies, LLC | 229.8K | $8.16M | — | Held |
| Boxer Capital Management, LLC | 225K | $7.99M | — | New |
| Cormorant Asset Management, LP | 225K | $7.99M | — | Held |
| Seven Fleet Capital Management LP | 214.1K | $7.6M | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 199K | $7.07M | — | Held |
| READYSTATE ASSET MANAGEMENT LP | 6M | $7.05M | — | Held |
| Polar Capital Holdings Plc | 5.5M | $6.45M | — | Held |
| RHUMBLINE ADVISERS | 180.2K | $6.4M | — | Held |
| SEI INVESTMENTS CO | 179.4K | $6.37M | — | Held |
| Connor, Clark & Lunn Investment Management Ltd. | 175.9K | $6.25M | — | Held |
| Swiss National Bank | 165.4K | $5.88M | — | Held |
| Skandinaviska Enskilda Banken AB (publ) | 164.4K | $5.84M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 164.1K | $5.83M | — | Held |
| TUDOR INVESTMENT CORP ET AL | 159.9K | $5.68M | — | New |
| Squarepoint Ops LLC | 156K | $5.54M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 155.5K | $5.52M | — | Held |
| WELLS FARGO & COMPANY/MN | 153.6K | $5.46M | — | Held |
| Nicholas Investment Partners, LP | 151.1K | $5.37M | — | Held |
| SSI INVESTMENT MANAGEMENT LLC | 4.45M | $5.21M | — | Held |
| ADVENT CAPITAL MANAGEMENT /DE/ | 4.4M | $5.18M | — | Held |
| Informed Momentum Co LLC | 134.3K | $4.77M | — | Held |
| DIADEMA PARTNERS LP | 131.9K | $4.68M | — | Held |
| Wellesley Asset Management | 4M | $4.65M | — | Held |
| BOOTHBAY FUND MANAGEMENT, LLC | 127.1K | $4.51M | — | Held |
| LPL Financial LLC | 124.2K | $4.41M | — | Held |
| Icahn Capital | 121.8K | $4.33M | — | Held |
| PLATINUM INVESTMENT MANAGEMENT LTD | 121.2K | $4.31M | — | Held |
| PERCEPTIVE ADVISORS LLC | 121.1K | $4.3M | — | Held |
| PRUDENTIAL FINANCIAL INC | 120.2K | $4.27M | — | Held |
| Soleus Capital Management, L.P. | 120K | $4.26M | — | Held |
| Pictet Asset Management Holding SA | 112.5K | $4.23M | — | Held |
| Walleye Capital LLC | 114.5K | $4.07M | — | Held |
| PRINCIPAL FINANCIAL GROUP INC | 111.8K | $3.97M | — | Held |
| Rafferty Asset Management, LLC | 111.1K | $3.95M | — | Held |
| DEUTSCHE BANK AG\ | 109.1K | $3.88M | — | Held |
| NEOS Investment Management LLC | 107.9K | $3.83M | — | Held |
| TEMA ETFS LLC | 106.3K | $3.78M | — | Held |
| Aquatic Capital Management LLC | 106.2K | $3.77M | — | Held |
| Knott David M Jr | 102K | $3.62M | — | Held |
| AIHC Capital Management Ltd | 100K | $3.55M | — | Held |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 100K | $3.55M | — | Held |
| CAPSTONE INVESTMENT ADVISORS, LLC | 3M | $3.53M | — | Held |
| Legal & General Group Plc | 98.5K | $3.5M | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 96K | $3.46M | — | Held |
| NEXTBio Capital Management LP | 95.8K | $3.4M | — | Held |
| Y-Intercept (Hong Kong) Ltd | 94.8K | $3.37M | — | Held |
| DV Trading LLC | 92.1K | $3.27M | — | Held |
| Creative Planning | 89.9K | $3.19M | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 83.7K | $2.97M | — | Held |
| Maven Securities LTD | 82.8K | $2.94M | — | Held |
| MetLife Investment Management, LLC | 77.5K | $2.75M | — | Held |
| Jefferies Financial Group Inc. | 75.1K | $2.67M | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 74.2K | $2.64M | — | Held |
| PRELUDE CAPITAL MANAGEMENT, LLC | 72.4K | $2.57M | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 71.1K | $2.54M | — | Held |
| CITIGROUP INC | 68.7K | $2.44M | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 61.6K | $2.19M | — | Held |
| Verition Fund Management LLC | 59.5K | $2.11M | — | Held |
| Ares Systematic Credit Ltd | 1.7M | $2M | — | Held |
| TD Asset Management Inc | 56.3K | $2M | — | Held |
| Trexquant Investment LP | 56.1K | $1.99M | — | Held |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 53.3K | $1.98M | — | Held |
| LMR Partners LLP | 54.4K | $1.93M | — | Held |
| GILDER GAGNON HOWE & CO LLC | 53.3K | $1.89M | — | Held |
| VICTORY CAPITAL MANAGEMENT INC | 51.6K | $1.83M | — | Held |
| Jain Global LLC | 48.1K | $1.71M | — | Held |
| Fisher Asset Management, LLC | 47.9K | $1.7M | — | Held |
| Persistent Asset Partners Ltd | 47.5K | $1.69M | $475.8K | Added$1.36M |
| Pier Capital, LLC | 46.3K | $1.64M | — | Held |
| Cinctive Capital Management LP | 44.7K | $1.59M | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 44.4K | $1.58M | — | Held |
| PROFUND ADVISORS LLC | 42.7K | $1.52M | — | Held |
| Police & Firemen's Retirement System of New Jersey | 37.5K | $1.33M | — | Held |
| SEVEN GRAND MANAGERS, LLC | 35K | $1.24M | — | Held |
| JANE STREET GROUP, LLC | 1M | $1.19M | — | Held |
| Optimize Financial Inc | 33K | $1.17M | — | Held |
| PALISADE CAPITAL MANAGEMENT, LP | 1M | $1.17M | — | Held |
| Kohlberg Kravis Roberts & Co. L.P. | 990K | $1.16M | — | Held |
| Legato Capital Management LLC | 32.7K | $1.16M | — | Held |
| SECTORAL ASSET MANAGEMENT INC | 32.7K | $1.16M | — | Held |
| Allianz Asset Management GmbH | 32.6K | $1.16M | — | Held |
| ProShare Advisors LLC | 32K | $1.14M | — | Held |
| GABELLI FUNDS LLC | 950K | $1.12M | — | Held |
| Harvest Investment Services, LLC | 30.7K | $1.09M | — | Held |
| STRS OHIO | 30.5K | $1.08M | — | Held |
| TWINBEECH CAPITAL LP | 29.3K | $1.04M | — | Held |
| State of New Jersey Common Pension Fund D | 28.6K | $1.02M | — | Held |
| Engineers Gate Manager LP | 26.4K | $936.6K | — | Held |
| BANK OF HAWAII | 26.1K | $928.6K | — | Held |
| China Universal Asset Management Co., Ltd. | 25K | $888.5K | — | Held |
| DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD. | 24.2K | $859.6K | — | Held |
| ARIZONA STATE RETIREMENT SYSTEM | 23.3K | $829.2K | — | Held |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 23.1K | $822K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 22.4K | $797K | — | Held |
| Campbell & CO Investment Adviser LLC | 18.9K | $672.7K | — | Held |
| Atom Investors LP | 18.1K | $643.2K | — | Held |
| KLP KAPITALFORVALTNING AS | 17.8K | $632.3K | — | Held |
| FARALLON CAPITAL MANAGEMENT LLC | 17K | $603.8K | $359.7K | Added$359.7K |
| ROYAL BANK OF CANADA | 16.9K | $599K | — | Held |
| AGF MANAGEMENT LTD | 500K | $585.4K | — | Held |
| Acasta Partners UK LLP | 500K | $582.4K | — | Held |
| ENVESTNET ASSET MANAGEMENT INC | 15.6K | $553.9K | — | Held |
| TWO SIGMA ADVISERS, LP | 14.4K | $511.1K | — | Held |
| WINTON GROUP Ltd | 14.4K | $510.8K | — | Held |
| OmniStar Financial Group, Inc. | 14.3K | $508K | — | Held |
| Bridgefront Capital, LLC | 14.2K | $503.9K | — | Held |
| PSP Research LLC | 13.2K | $470K | — | Held |
| TWO SIGMA INVESTMENTS, LP | 12.6K | $447.6K | — | Held |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 12.4K | $441.9K | — | Held |
| Ameritas Investment Partners, Inc. | 11.3K | $400.8K | — | Held |
| XPONANCE LLC | 10.9K | $388.7K | — | Held |
| Allspring Global Investments Holdings, LLC | 10.5K | $365.6K | — | Held |
| BANK OF MONTREAL /CAN/ | 9.89K | $351.4K | — | Held |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 9.57K | $339.9K | — | Held |
| CIBC WORLD MARKETS CORP | 9.2K | $326.7K | — | Held |
| MACKENZIE FINANCIAL CORP | 8.59K | $318.3K | — | Held |
| OSAIC HOLDINGS, INC. | 8.49K | $301.4K | — | Held |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 8.28K | $294.2K | — | Held |
| Tower Research Capital LLC (TRC) | 7.56K | $268.6K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 7.46K | $264.9K | — | Held |
| OPAL CAPITAL LLC | 6.96K | $264.2K | — | Held |
| Graham Capital Management, L.P. | 7.42K | $263.5K | — | Held |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 7.35K | $261.2K | — | Held |
| AlphaQuest LLC | 7.2K | $255.7K | — | Held |
| Mariner, LLC | 7.15K | $251.5K | — | Held |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 6.84K | $243.1K | — | Held |
| AXQ CAPITAL, LP | 6.6K | $234.5K | — | Held |
| 49 WEALTH MANAGEMENT, LLC | 6.43K | $228.4K | — | Held |
| Virtus Investment Advisers, LLC | 6.32K | $224.4K | — | Held |
| Aigen Investment Management, LP | 5.66K | $201.1K | — | Held |
| Quantbot Technologies LP | 5.42K | $192.3K | — | Held |
| Gordian Capital Singapore Pte Ltd | 4.5K | $159.8K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 3.02K | $107.1K | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.56M | $91.1K | — | Held |
| Duquesne Family Office | 2.21M | $78.7K | — | Held |
| Steward Partners Investment Advisory, LLC | 2.16K | $76.7K | — | Held |
| LORD, ABBETT & CO. LLC | 10.1M | $76.1K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 1.85K | $65.9K | — | Held |
| Caitong International Asset Management Co., Ltd | 1.74K | $61.7K | — | Held |
| GAMMA Investing LLC | 1.37K | $48.6K | — | Held |
| Sterling Capital Management LLC | 1.32K | $46.8K | — | Held |
| PNC Financial Services Group, Inc. | 1.28K | $45.5K | — | Held |
| LORING WOLCOTT & COOLIDGE FIDUCIARY ADVISORS LLP/MA | 1K | $38.5K | — | Held |
| COMERICA BANK | 1.06K | $37.5K | — | Held |
| Global Retirement Partners, LLC | 1.04K | $37.1K | — | Held |
| Sandia Investment Management LP | 1K | $35.5K | — | Held |
| EverSource Wealth Advisors, LLC | 708 | $25.1K | — | Held |
| FIRST HORIZON CORP | 635 | $22.6K | — | Held |
| Optiver Holding B.V. | 619 | $22K | — | Held |
| WPG Advisers, LLC | 550 | $19.5K | — | Held |
| Kemnay Advisory Services Inc. | 460 | $16.3K | — | Held |
| NewEdge Advisors, LLC | 13K | $15.2K | — | Held |
| Wilmington Savings Fund Society, FSB | 380 | $13.5K | — | Held |
| Hilton Head Capital Partners, LLC | 332 | $11.8K | — | Held |
| Rockefeller Capital Management L.P. | 325 | $11.5K | — | Held |
| Smartleaf Asset Management LLC | 290 | $10.8K | — | Held |
| ROTHSCHILD INVESTMENT LLC | 274 | $9.73K | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 267 | $9.48K | — | Held |
| J.Safra Asset Management Corp | 255 | $9.06K | — | Held |
| NWI MANAGEMENT LP | 241.7K | $8.58K | — | New |
| ALGERT GLOBAL LLC | 227.9K | $8.09K | — | Held |
| Essential Partners LLC | 197 | $7K | $4K | Added$4.28K |