| SB INVESTMENT ADVISERS (UK) LTD | 27.9M | $236.1M | — | Held |
| Commodore Capital LP | 17M | $143.8M | — | Held |
| Point72 Asset Management, L.P. | 13.9M | $117.2M | — | Held |
| BlackRock, Inc. | 13.2M | $111.9M | — | Held |
| Casdin Capital, LLC | 13M | $110M | — | Held |
| Vanguard | 9.69M | $82M | — | Held |
| Bellevue Group AG | 8.35M | $70.6M | — | Held |
| State Street | 6.43M | $54.4M | — | Held |
| Nextech Invest, Ltd. | 4.7M | $39.8M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 3.41M | $28.8M | — | Held |
| TCG Crossover Management, LLC | 3.22M | $27.2M | — | Held |
| Spruce Street Capital LP | 2.98M | $25.2M | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 2.48M | $21M | — | Held |
| MPM BIOIMPACT LLC | 2.23M | $18.9M | — | Held |
| Balyasny Asset Management L.P. | 2.1M | $17.8M | — | Held |
| MORGAN STANLEY | 2.02M | $17.1M | $5.72M | Added$7.87M |
| PERCEPTIVE ADVISORS LLC | 1.9M | $16.1M | — | Held |
| GOLDMAN SACHS GROUP INC | 1.86M | $15.7M | — | Held |
| Alphabet Inc. | 1.57M | $13.3M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 1.56M | $13.2M | — | Held |
| Kynam Capital Management, LP | 1.42M | $12M | — | Held |
| TWO SIGMA ADVISERS, LP | 1.29M | $10.9M | — | Held |
| Icahn Capital | 1.16M | $9.84M | — | Held |
| BAKER BROS. ADVISORS LP | 1.16M | $9.81M | — | Held |
| ExodusPoint Capital Management, LP | 1.14M | $9.66M | — | Held |
| NORTHERN TRUST CORP | 1.14M | $9.63M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.14M | $9.62M | — | Held |
| BANK OF AMERICA CORP /DE/ | 1.04M | $8.81M | $3.37M | Added$2.56M |
| Foresite Capital Management IV, LLC | 1M | $8.46M | — | Held |
| Kalehua Capital Management LLC | 901.5K | $7.63M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 896.9K | $7.59M | — | Held |
| Invesco Ltd. | 865.5K | $7.32M | — | Held |
| NORGES BANK | 837.4K | $7.08M | $4.89M | Cut−$5.06M |
| Woodline Partners LP | 679.1K | $5.75M | — | Held |
| Renaissance Technologies | 647.9K | $5.48M | — | Held |
| Allianz Asset Management GmbH | 560.3K | $4.74M | — | Held |
| HighVista Strategies LLC | 545.1K | $4.61M | — | Held |
| ArrowMark Colorado Holdings LLC | 541.1K | $4.58M | — | Held |
| Elmind Capital, LP | 536.9K | $4.54M | — | Held |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 500K | $4.23M | — | Held |
| Eversept Partners, LP | 489.1K | $4.14M | — | Held |
| Trexquant Investment LP | 472K | $3.99M | — | Held |
| Rhenman & Partners Asset Management AB | 460K | $3.89M | — | Held |
| Hudson Bay Capital Management LP | 451.5K | $3.82M | — | New |
| AMERICAN CENTURY COMPANIES INC | 432.5K | $3.66M | — | Held |
| JPMORGAN CHASE & CO | 426K | $3.6M | — | Held |
| CONGRESS ASSET MANAGEMENT CO | 414.2K | $3.5M | — | Held |
| BARCLAYS PLC | 414.1K | $3.5M | $1.34M | Added$1.09M |
| SILVERARC CAPITAL MANAGEMENT, LLC | 398.2K | $3.37M | — | Held |
| Connor, Clark & Lunn Investment Management Ltd. | 389.6K | $3.3M | — | Held |
| Bank of New York Mellon Corp | 378.7K | $3.2M | — | Held |
| Susquehanna Portfolio Strategies, LLC | 339.1K | $2.87M | — | Held |
| Nuveen, LLC | 300.5K | $2.54M | — | Held |
| UBS Group AG | 296K | $2.5M | — | Held |
| RAYMOND JAMES FINANCIAL INC | 259.4K | $2.19M | — | Held |
| Raiffeisen Bank International AG | 250K | $2.09M | — | Held |
| Swiss National Bank | 238K | $2.01M | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 222.9K | $1.89M | — | Held |
| RHUMBLINE ADVISERS | 215.7K | $1.83M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 209.8K | $1.78M | — | Held |
| Rafferty Asset Management, LLC | 193.8K | $1.64M | — | Held |
| OSAIC HOLDINGS, INC. | 186.4K | $1.58M | — | Held |
| TD Asset Management Inc | 182K | $1.54M | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 177.5K | $1.49M | — | Held |
| IEQ CAPITAL, LLC | 162.3K | $1.37M | — | Held |
| Fidelity | 162.2K | $1.37M | — | Held |
| WELLS FARGO & COMPANY/MN | 157.9K | $1.34M | — | Held |
| XTX Topco Ltd | 157.4K | $1.33M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 145.3K | $1.23M | — | Held |
| ALPS ADVISORS INC | 142.3K | $1.2M | — | Held |
| Sanctuary Advisors, LLC | 142.2K | $1.2M | — | New |
| DEUTSCHE BANK AG\ | 124K | $1.05M | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 117.7K | $995.5K | — | Held |
| Citadel | 114.1K | $965.6K | — | Held |
| NEOS Investment Management LLC | 113.2K | $957.9K | — | Held |
| TEMA ETFS LLC | 111.6K | $943.8K | — | Held |
| Legal & General Group Plc | 109.2K | $923.9K | — | Held |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. | 105K | $887.9K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 101.2K | $855.8K | — | Held |
| ICONIQ Capital, LLC | 94.7K | $801.1K | — | Held |
| Squarepoint Ops LLC | 94.2K | $797K | — | Held |
| Man Group plc | 87K | $736.3K | — | Held |
| Creative Planning | 85.8K | $726.2K | — | Held |
| TUDOR INVESTMENT CORP ET AL | 84.2K | $712K | $247.7K | Added$313K |
| Jump Financial, LLC | 82.6K | $698.4K | — | Held |
| Engineers Gate Manager LP | 78.4K | $663K | — | Held |
| MetLife Investment Management, LLC | 77.5K | $656K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 76.7K | $647.5K | — | Held |
| JANE STREET GROUP, LLC | 76.5K | $647K | — | Held |
| Seven Fleet Capital Management LP | 73K | $617.6K | — | Held |
| PROFUND ADVISORS LLC | 72.6K | $614.1K | — | Held |
| Jain Global LLC | 66.6K | $563.3K | — | Held |
| Allspring Global Investments Holdings, LLC | 65.4K | $535.4K | — | Held |
| Schonfeld Strategic Advisors LLC | 61.9K | $523.3K | — | Held |
| FOX RUN MANAGEMENT, L.L.C. | 60.2K | $509.3K | — | Held |
| Private Capital Advisors, Inc. | 59.3K | $501.8K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 57.2K | $484.2K | — | Held |
| BANK OF MONTREAL /CAN/ | 56.5K | $477.6K | — | Held |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 55K | $465.2K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 53.2K | $450.1K | — | Held |
| MAYPORT, LLC | 49.7K | $420.3K | — | Held |
| FRANKLIN RESOURCES INC | 48.9K | $413.8K | — | Held |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 47.6K | $389.3K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 45.8K | $387.5K | — | Held |
| Intellectus Partners, LLC | 43.9K | $371.6K | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 42K | $355.3K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 48K | $352.2K | — | Held |
| AlphaQuest LLC | 39.4K | $333.7K | — | Held |
| BRANDYWINE MANAGERS, LLC | 38.4K | $325.1K | — | Held |
| Cresset Asset Management, LLC | 37.1K | $313.7K | $120.2K | Added$120.2K |
| Police & Firemen's Retirement System of New Jersey | 37K | $313.1K | — | Held |
| JANUS HENDERSON GROUP PLC | 36.9K | $312.5K | — | Held |
| CAPTRUST FINANCIAL ADVISORS | 35.6K | $300.9K | — | Held |
| LPL Financial LLC | 34.1K | $288.9K | — | Held |
| ARIZONA STATE RETIREMENT SYSTEM | 33.5K | $283.7K | — | Held |
| ProShare Advisors LLC | 33.4K | $282.5K | — | Held |
| EntryPoint Capital, LLC | 33.2K | $281.2K | — | Held |
| Virtus Investment Advisers, LLC | 33.1K | $280.3K | — | Held |
| Dynamic Technology Lab Private Ltd | 32.7K | $276K | — | Held |
| CITIGROUP INC | 30.9K | $261.7K | — | Held |
| VARCOV Co. | 29.3K | $247.8K | — | Held |
| GROUP ONE TRADING LLC | 29K | $244.9K | — | Held |
| PDT Partners, LLC | 28.9K | $244.5K | — | Held |
| China Universal Asset Management Co., Ltd. | 28.2K | $238.9K | — | Held |
| Fiduciary Trust Co | 28K | $236.6K | — | Held |
| Vanguard Personalized Indexing Management, LLC | 27.6K | $233.4K | — | Held |
| Brooklyn Investment Group | 27.1K | $228.3K | — | Held |
| Blueshift Asset Management, LLC | 26.8K | $226.8K | — | Held |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 25.8K | $218.3K | — | Held |
| SEI INVESTMENTS CO | 25.6K | $216.8K | — | Held |
| Pallas Capital Advisors LLC | 25.1K | $212.5K | — | Held |
| KLP KAPITALFORVALTNING AS | 24.7K | $209K | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 24.6K | $207.9K | — | Held |
| Graham Capital Management, L.P. | 23.1K | $195.6K | — | Held |
| Erste Asset Management GmbH | 23.1K | $194.3K | — | Held |
| Cerity Partners LLC | 21K | $178K | — | Held |
| Callan Family Office, LLC | 20.5K | $173.7K | — | Held |
| Merit Financial Group, LLC | 20.5K | $173.3K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 20K | $169.2K | — | Held |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 17.5K | $147.8K | — | Held |
| Focus Partners Wealth | 17.3K | $146.6K | — | Held |
| Quantinno Capital Management LP | 17.3K | $146.2K | — | Held |
| AssuredPartners Investment Advisors, LLC | 16.1K | $136.4K | — | Held |
| WINTON GROUP Ltd | 16K | $135.4K | — | Held |
| Pictet Asset Management Holding SA | 15.1K | $127.3K | — | Held |
| VICTORY CAPITAL MANAGEMENT INC | 15K | $127K | — | Held |
| Caitong International Asset Management Co., Ltd | 13.6K | $115.4K | — | Held |
| Abel Hall, LLC | 13K | $109.8K | — | Held |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 12.9K | $109.1K | — | Held |
| MERCER GLOBAL ADVISORS INC /ADV | 12.8K | $108.6K | — | Held |
| J. Goldman & Co LP | 12.6K | $106.2K | — | Held |
| EP Wealth Advisors, LLC | 12.5K | $105.8K | — | Held |
| Russell Investments Group, Ltd. | 12.5K | $105.4K | — | Held |
| Duncan Williams Asset Management, LLC | 11.8K | $99.9K | — | Held |
| QUADRANT CAPITAL GROUP LLC | 11.8K | $99.8K | — | Held |
| OPAL CAPITAL LLC | 11.4K | $98.6K | — | Held |
| 49 WEALTH MANAGEMENT, LLC | 11.4K | $96.5K | — | Held |
| Ameritas Investment Partners, Inc. | 11.2K | $94.6K | — | Held |
| XPONANCE LLC | 11K | $93.1K | — | Held |
| Focus Partners Advisor Solutions, LLC | 10.7K | $90.2K | — | Held |
| DRW Securities, LLC | 10.1K | $85.7K | — | Held |
| PORTLAND INVESTMENT COUNSEL INC. | 10K | $84.6K | — | Held |
| Steward Partners Investment Advisory, LLC | 8.9K | $75.3K | — | Held |
| Plante Moran Financial Advisors, LLC | 8.76K | $74.1K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 8.42K | $71.3K | — | Held |
| Sterling Capital Management LLC | 8.12K | $68.7K | — | Held |
| Essential Partners LLC | 5.35K | $45.2K | $17.3K | Added$17.3K |
| US BANCORP \DE\ | 5.13K | $43.4K | — | Held |
| PNC Financial Services Group, Inc. | 4.61K | $39K | — | Held |
| Smartleaf Asset Management LLC | 4.43K | $37K | — | Held |
| Farther Finance Advisors, LLC | 4.14K | $35K | — | Held |
| ROYAL BANK OF CANADA | 4.06K | $35K | — | Held |
| Torren Management, LLC | 3.54K | $30K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 3.41K | $28.8K | — | Held |
| SIGNATUREFD, LLC | 3.12K | $26.4K | — | Held |
| EverSource Wealth Advisors, LLC | 2.21K | $18.7K | — | Held |
| HAGER INVESTMENT MANAGEMENT SERVICES, LLC | 2.18K | $18.4K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 2.07K | $17.5K | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.65M | $13.9K | — | Held |
| SBI Securities Co., Ltd. | 1.45K | $12.3K | — | Held |
| Allworth Financial LP | 1.33K | $11.3K | $4.32K | Added$3.79K |
| Parallel Advisors, LLC | 1.19K | $10.1K | — | Held |
| WEBSTER BANK, N. A. | 1K | $8.46K | — | Held |
| UMB Bank, n.a. | 735 | $6.22K | — | Held |
| Red Tortoise LLC | 698 | $5.91K | — | Held |
| Tower Research Capital LLC (TRC) | 681 | $5.76K | — | Held |
| CIBC Private Wealth Group LLC | 680 | $5.75K | — | Held |
| Keating Financial Advisory Services, Inc. | 679 | $5.74K | — | Held |
| COMERICA BANK | 664 | $5.62K | — | Held |
| IFP Advisors, Inc | 576 | $4.87K | $1.87K | Added$1.87K |
| Versant Capital Management, Inc | 493 | $4.17K | — | Held |
| ROTHSCHILD INVESTMENT LLC | 469 | $3.97K | — | Held |
| BESSEMER GROUP INC | 457.9K | $3.87K | — | Held |
| ACADIAN ASSET MANAGEMENT LLC | 456.6K | $3.86K | — | Held |
| Rockefeller Capital Management L.P. | 454 | $3.84K | — | Held |
| GAMMA Investing LLC | 354 | $3K | — | Held |
| Fortitude Family Office, LLC | 301 | $2.55K | — | Held |
| True Wealth Design, LLC | 278 | $2.35K | — | Held |
| SG Americas Securities, LLC | 220.9K | $1.87K | — | Held |
| Hughes Financial Services, LLC | 218 | $1.84K | — | Held |
| MAI Capital Management | 181 | $1.53K | — | Held |
| Cornerstone Financial Management LLC | 162 | $1.37K | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 154 | $1.3K | — | Held |
| ALGERT GLOBAL LLC | 146.5K | $1.24K | — | Held |
| Global Retirement Partners, LLC | 130 | $1.1K | — | Held |
| Parkside Financial Bank & Trust | 129 | $1.09K | — | Held |
| Your Advocates Ltd., LLP | 100 | $846 | — | Held |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 93 | $787 | — | Held |
| CWM, LLC | 67.6K | $572 | — | Held |
| DekaBank Deutsche Girozentrale | 60K | $532 | — | Held |
| Sunbelt Securities, Inc. | 52 | $440 | — | Held |
| SageView Advisory Group, LLC | 40 | $339 | — | Held |
| Clearstead Advisors, LLC | 34 | $285 | — | Held |
| HRT FINANCIAL LP | 30.6K | $259 | — | Held |
| Arax Advisory Partners | 19 | $161 | — | Held |
| Transamerica Financial Advisors, LLC | 13 | $110 | — | Held |
| Aster Capital Management (DIFC) Ltd | 10 | $85 | — | Held |
| CANADA LIFE ASSURANCE Co | 8.62K | $73 | — | Held |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 5.89K | $50 | — | Held |
| FNY Investment Advisers, LLC | 5K | $42 | $16 | Cut−$10 |
| AMALGAMATED BANK | 4.42K | $37 | — | Held |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1.77K | $15 | — | Held |
| Daiwa Securities Group Inc. | 486 | $4 | — | Held |
| Avion Wealth | 136 | $1 | — | Held |
| Covestor Ltd | 24 | $0 | — | Held |