| Fidelity | 7.26M | $220.1M | — | Held |
| VR ADVISER, LLC | 4.15M | $125.7M | — | Held |
| Fairmount Funds Management LLC | 3.71M | $112.3M | — | Held |
| BlackRock, Inc. | 3.54M | $107.3M | — | Held |
| Viking Global | 2.67M | $80.8M | — | Held |
| Vanguard | 2.45M | $74.4M | — | Held |
| Deep Track Capital, LP | 2.16M | $65.5M | — | Held |
| RTW INVESTMENTS, LP | 2.06M | $62.4M | — | Held |
| Commodore Capital LP | 1.75M | $53.1M | — | Held |
| Paradigm Biocapital Advisors LP | 1.71M | $51.8M | — | Held |
| PERCEPTIVE ADVISORS LLC | 1.48M | $44.8M | — | Held |
| State Street | 1.38M | $41.9M | — | Held |
| Avoro Capital Advisors LLC | 1.33M | $40.4M | — | Held |
| Blackstone Inc. | 1.17M | $35.3M | — | New |
| Polar Capital Holdings Plc | 978.3K | $29.7M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 942.5K | $28.6M | — | Held |
| FRANKLIN RESOURCES INC | 938.4K | $28.4M | — | Held |
| Affinity Asset Advisors, LLC | 802.3K | $24.3M | — | Held |
| MERCER GLOBAL ADVISORS INC /ADV | 745.3K | $22.6M | — | Held |
| Citadel | 726.1K | $22M | — | Held |
| Avidity Partners Management LP | 660.4K | $20M | — | Held |
| Point72 Asset Management, L.P. | 600K | $18.2M | — | Held |
| Woodline Partners LP | 574.6K | $17.4M | — | Held |
| Cormorant Asset Management, LP | 533.3K | $16.2M | — | Held |
| Synergy Asset Management, LLC | 458.9K | $13.9M | — | Held |
| SR One Capital Management, LP | 430.3K | $13M | — | Held |
| Candriam S.C.A. | 400.5K | $12.1M | — | Held |
| Cable Car Capital, LP | 400K | $12.1M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 329.5K | $9.99M | — | Held |
| NORTHERN TRUST CORP | 280.9K | $8.51M | — | Held |
| UBS Group AG | 271K | $8.21M | — | Held |
| Soleus Capital Management, L.P. | 190K | $5.76M | — | Held |
| GREAT POINT PARTNERS LLC | 183.3K | $5.56M | — | Held |
| BARCLAYS PLC | 173.3K | $5.25M | $1.06M | Added$3.42M |
| Invesco Ltd. | 143.1K | $4.34M | — | Held |
| BANK OF AMERICA CORP /DE/ | 139.3K | $4.22M | $875.3K | Added$2.7M |
| Longaeva Partners L.P. | 128.1K | $3.88M | — | Held |
| Moody Aldrich Partners LLC | 126.8K | $3.84M | — | Held |
| MORGAN STANLEY | 122.2K | $3.7M | $1.35M | Added$1.11M |
| DEUTSCHE BANK AG\ | 119.3K | $3.62M | — | Held |
| Kalehua Capital Management LLC | 118.5K | $3.59M | — | Held |
| Sio Capital Management, LLC | 118.1K | $3.58M | — | Held |
| Bank of New York Mellon Corp | 114.2K | $3.46M | — | Held |
| Alyeska Investment Group, L.P. | 100K | $3.03M | — | Held |
| GOLDMAN SACHS GROUP INC | 93K | $2.82M | — | Held |
| Nuveen, LLC | 86.3K | $2.62M | — | Held |
| BRAIDWELL LP | 84.8K | $2.57M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 84.7K | $2.57M | — | Held |
| Secure Asset Management, LLC | 81.7K | $2.48M | — | Held |
| TD Asset Management Inc | 79.9K | $2.42M | — | Held |
| D. E. Shaw & Co., Inc. | 76.4K | $2.32M | — | Held |
| Aberdeen Group plc | 75.7K | $2.29M | — | Held |
| B Group, Inc. | 75K | $2.27M | — | Held |
| Palo Alto Investors LP | 60K | $1.82M | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 61.4K | $1.8M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 58.7K | $1.78M | — | Held |
| AMERICAN CENTURY COMPANIES INC | 57.1K | $1.73M | — | Held |
| KENNEDY CAPITAL MANAGEMENT LLC | 48.7K | $1.48M | — | Held |
| WELLS FARGO & COMPANY/MN | 43.3K | $1.31M | — | Held |
| Swiss National Bank | 43K | $1.3M | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 42.5K | $1.29M | — | Held |
| RHUMBLINE ADVISERS | 41K | $1.24M | — | Held |
| ALPS ADVISORS INC | 39.8K | $1.2M | — | Held |
| Rafferty Asset Management, LLC | 38.5K | $1.17M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 37.8K | $1.15M | — | Held |
| Verition Fund Management LLC | 35.7K | $1.08M | — | Held |
| Financial Enhancement Group LLC | 31.3K | $1.08M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 28.6K | $865.8K | — | Held |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 29.2K | $849.8K | — | Held |
| Squarepoint Ops LLC | 27.7K | $838.7K | — | Held |
| Voleon Capital Management LP | 23.5K | $713.7K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 23K | $696.2K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 21.7K | $656.5K | — | Held |
| MetLife Investment Management, LLC | 21.4K | $647.5K | — | Held |
| ADAR1 Capital Management, LLC | 20.8K | $631.7K | — | Held |
| JPMORGAN CHASE & CO | 20.4K | $618.8K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 20.2K | $608.1K | — | Held |
| Hudson Bay Capital Management LP | 20K | $606.2K | — | New |
| GLENMEDE TRUST CO NA | 19.5K | $590.6K | — | Held |
| Legal & General Group Plc | 18.7K | $568.1K | — | Held |
| Brookwood Investment Group LLC | 16.6K | $502.2K | — | Held |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 15.4K | $467K | — | Held |
| ENVESTNET ASSET MANAGEMENT INC | 15.2K | $462.1K | — | Held |
| AlphaQuest LLC | 14.9K | $451.6K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 14.8K | $449K | — | Held |
| PROFUND ADVISORS LLC | 14.6K | $443.2K | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 14.2K | $431.7K | — | Held |
| Resolute Capital Asset Partners LLC | 12.5K | $378.9K | — | Held |
| JANUS HENDERSON GROUP PLC | 12.1K | $366.8K | — | Held |
| AlphaCentric Advisors LLC | 10.9K | $329.8K | — | Held |
| ALTFEST L J & CO INC | 10.9K | $329.1K | — | Held |
| Allianz Asset Management GmbH | 10.3K | $312.2K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 10.2K | $309.4K | — | Held |
| CITIGROUP INC | 9.83K | $297.9K | — | Held |
| SEI INVESTMENTS CO | 9.68K | $293.3K | — | Held |
| Brevan Howard Capital Management LP | 9.42K | $285.4K | — | Held |
| ProShare Advisors LLC | 9.19K | $278.5K | — | Held |
| Virtus Investment Advisers, LLC | 8.81K | $267.2K | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 8.66K | $262.6K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 8.6K | $260.7K | — | Held |
| KLP KAPITALFORVALTNING AS | 8K | $242.5K | — | Held |
| China Universal Asset Management Co., Ltd. | 7.89K | $239.1K | — | Held |
| Creative Planning | 7.7K | $233.3K | — | Held |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 7.45K | $225.7K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 5.89K | $178.6K | — | Held |
| Seven Fleet Capital Management LP | 5.24K | $158.8K | — | Held |
| Ameritas Investment Partners, Inc. | 3.13K | $94.9K | — | Held |
| Russell Investments Group, Ltd. | 3.04K | $92.2K | — | Held |
| US BANCORP \DE\ | 2.92K | $88.7K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 2.35K | $71.3K | — | Held |
| Sterling Capital Management LLC | 2.22K | $67.4K | — | Held |
| Caitong International Asset Management Co., Ltd | 2.21K | $67.1K | — | Held |
| Remedium Capital Partners, LLC | 1.55M | $47.1K | — | Held |
| PNC Financial Services Group, Inc. | 1.45K | $44K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 1.3K | $36.6K | — | Held |
| ROYAL BANK OF CANADA | 1.14K | $34K | — | Held |
| Stone House Investment Management, LLC | 1K | $30.3K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 950 | $28.8K | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 649.3K | $19.7K | — | Held |
| Balyasny Asset Management L.P. | 536 | $16.2K | — | Held |
| Tower Research Capital LLC (TRC) | 495 | $15K | — | Held |
| DV Trading LLC | 492 | $14.9K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 282 | $8.55K | — | Held |
| GROUP ONE TRADING LLC | 200 | $6.06K | — | Held |
| Activest Wealth Management | 166 | $5.03K | — | Held |
| J.Safra Asset Management Corp | 155 | $4.7K | — | Held |
| Allworth Financial LP | 114 | $3.46K | $55 | Added$3.36K |
| GAMMA Investing LLC | 101 | $3.06K | — | Held |
| Essential Partners LLC | 27 | $818 | $299 | Added$299 |
| True Wealth Design, LLC | 26 | $789 | — | Held |
| Aster Capital Management (DIFC) Ltd | 25 | $758 | — | Held |
| Cornerstone Financial Management LLC | 21 | $637 | — | Held |
| Parallel Advisors, LLC | 20 | $606 | — | Held |
| EverSource Wealth Advisors, LLC | 16 | $485 | — | Held |
| Larson Financial Group LLC | 13 | $394 | — | Held |
| Farther Finance Advisors, LLC | 10 | $303 | — | Held |
| SG Americas Securities, LLC | 8.28K | $251 | — | Held |
| OSAIC HOLDINGS, INC. | 4 | $121 | — | Held |
| IFP Advisors, Inc | 3 | $91 | $33 | Added$33 |
| AMALGAMATED BANK | 1.21K | $37 | — | Held |
| CIBC Private Wealth Group LLC | 1 | $30 | — | Held |
| CWM, LLC | 586 | $18 | — | Held |
| Daiwa Securities Group Inc. | 116 | $4 | — | Held |