| RA CAPITAL MANAGEMENT, L.P. | 4.18M | $66.9M | — | Held |
| Fidelity | 3.7M | $59.2M | — | Held |
| Alpha Wave Global, LP | 3.61M | $57.8M | — | Held |
| Versant Venture Management, LLC | 2.66M | $42.5M | — | Held |
| BlackRock, Inc. | 1.69M | $27.1M | — | Held |
| UBS Group AG | 1.57M | $25.1M | — | Held |
| Vanguard | 1.32M | $21.1M | — | Held |
| FRANKLIN RESOURCES INC | 1.1M | $17.5M | — | Held |
| 72 Investment Holdings, LLC | 1.02M | $16.3M | — | Held |
| TANG CAPITAL MANAGEMENT LLC | 865.2K | $13.8M | — | Held |
| INTRINSIC EDGE CAPITAL MANAGEMENT LLC | 569.7K | $9.12M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 539.3K | $8.63M | — | Held |
| State Street | 510.7K | $8.17M | — | Held |
| Squarepoint Ops LLC | 491.9K | $7.87M | — | Held |
| Aberdeen Group plc | 489.4K | $7.83M | — | Held |
| Alyeska Investment Group, L.P. | 463.5K | $7.42M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 461.1K | $7.38M | — | Held |
| Granahan Investment Management, LLC | 431.1K | $6.9M | — | Held |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 398.6K | $6.38M | — | Held |
| Candriam S.C.A. | 374.9K | $6M | — | Held |
| PRIMECAP MANAGEMENT CO/CA/ | 372.2K | $5.96M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 293.4K | $4.7M | — | Held |
| Vestal Point Capital, LP | 275K | $4.4M | — | Held |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 270.9K | $4.33M | — | Held |
| GOLDMAN SACHS GROUP INC | 257.9K | $4.13M | — | Held |
| Rock Springs Capital Management LP | 257.5K | $4.12M | — | Held |
| DISCOVERY CAPITAL MANAGEMENT, LLC / CT | 241.3K | $3.86M | — | Held |
| MORGAN STANLEY | 233.4K | $3.73M | −$7.14M | Cut−$10.1M |
| PLUSTICK MANAGEMENT LLC | 200K | $3.2M | — | Held |
| Skandinaviska Enskilda Banken AB (publ) | 185.6K | $2.97M | — | Held |
| Sovran Advisors, LLC | 160.1K | $2.9M | — | Held |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 174.7K | $2.8M | — | Held |
| Trexquant Investment LP | 173.2K | $2.77M | — | Held |
| PRELUDE CAPITAL MANAGEMENT, LLC | 170.2K | $2.72M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 169.1K | $2.71M | — | Held |
| NORTHERN TRUST CORP | 161.9K | $2.59M | — | Held |
| Blue Owl Capital Holdings LP | 150K | $2.4M | — | Held |
| AWM Investment Company, Inc. | 150K | $2.4M | — | Held |
| AMERIPRISE FINANCIAL INC | 136.9K | $2.19M | — | Held |
| SCOGGIN MANAGEMENT LP | 125K | $2M | — | Held |
| BANK OF AMERICA CORP /DE/ | 114.7K | $1.84M | −$3.51M | Cut−$14.4M |
| DIMENSIONAL FUND ADVISORS LP | 113.1K | $1.81M | — | Held |
| Woodline Partners LP | 100K | $1.6M | — | Held |
| NOMURA ASSET MANAGEMENT CO LTD | 96.8K | $1.55M | — | Held |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 83.2K | $1.4M | — | Held |
| XTX Topco Ltd | 85.8K | $1.37M | — | Held |
| Citadel | 80.6K | $1.29M | — | Held |
| VARCOV Co. | 78.8K | $1.26M | — | Held |
| TWO SIGMA ADVISERS, LP | 77.4K | $1.24M | — | Held |
| Ensign Peak Advisors, Inc | 77.3K | $1.24M | — | Held |
| BARCLAYS PLC | 72.4K | $1.16M | −$1.46M | Cut−$1.07M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 67.7K | $1.08M | — | Held |
| Vivaldi Capital Management LP | 64.1K | $1.02M | — | Held |
| FEDERATED HERMES, INC. | 62.6K | $1M | — | Held |
| Propel Bio Management, LLC | 59.1K | $945.4K | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 54.4K | $870.4K | — | Held |
| Knott David M Jr | 53.7K | $859.7K | — | Held |
| PERCEPTIVE ADVISORS LLC | 50K | $800K | — | Held |
| Rockefeller Capital Management L.P. | 48.1K | $769.1K | — | Held |
| JANE STREET GROUP, LLC | 46.8K | $749.6K | — | Held |
| Verition Fund Management LLC | 46.3K | $740.3K | — | Held |
| Qube Research & Technologies Ltd | 44.3K | $708.6K | — | Held |
| Bank of New York Mellon Corp | 44.1K | $704.9K | — | Held |
| ROYAL BANK OF CANADA | 43.2K | $691K | — | Held |
| Aquatic Capital Management LLC | 42.7K | $683.7K | — | Held |
| SECTORAL ASSET MANAGEMENT INC | 42.5K | $680K | — | Held |
| Jump Financial, LLC | 40.9K | $653.6K | — | Held |
| Y-Intercept (Hong Kong) Ltd | 40.6K | $649.8K | — | Held |
| Nuveen, LLC | 39.9K | $638.5K | — | Held |
| Virtus Investment Advisers, LLC | 37.7K | $602.8K | — | Held |
| MARSHALL WACE, LLP | 35.3K | $564K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 32.2K | $515.8K | — | Held |
| Engineers Gate Manager LP | 31.1K | $496.9K | — | Held |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 27.3K | $436.9K | — | Held |
| TD Asset Management Inc | 27K | $431.6K | — | Held |
| ExodusPoint Capital Management, LP | 23.1K | $370.4K | — | Held |
| Freestone Grove Partners LP | 23K | $367.5K | — | Held |
| WELLS FARGO & COMPANY/MN | 22.9K | $366.7K | — | Held |
| Swiss National Bank | 21.8K | $348.8K | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 20.8K | $334.9K | — | Held |
| RHUMBLINE ADVISERS | 20.3K | $324K | — | Held |
| AXQ CAPITAL, LP | 19.8K | $317.4K | — | Held |
| AlphaQuest LLC | 19.6K | $313.8K | — | Held |
| DNB Asset Management AS | 19.2K | $306.6K | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 18.9K | $301.6K | — | Held |
| Simplify Asset Management Inc. | 17.5K | $279.7K | — | Held |
| KELLEHER FINANCIAL ADVISORS | 17K | $272.4K | — | Held |
| Quantbot Technologies LP | 16.9K | $270.1K | — | Held |
| Marex Group plc | 16K | $256K | — | New |
| FOX RUN MANAGEMENT, L.L.C. | 15.7K | $251.8K | — | Held |
| Russell Investments Group, Ltd. | 15.5K | $247.4K | — | Held |
| Brevan Howard Capital Management LP | 15.4K | $246.5K | — | Held |
| Rinkey Investments | 15.2K | $243K | — | Held |
| CITIGROUP INC | 15K | $239.2K | — | Held |
| RAYMOND JAMES FINANCIAL INC | 14.2K | $227.2K | — | Held |
| Invesco Ltd. | 14K | $224.7K | — | Held |
| DEUTSCHE BANK AG\ | 13.8K | $221K | — | Held |
| ALLIANCEBERNSTEIN L.P. | 13.4K | $214.2K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 12K | $192.7K | — | Held |
| Entropy Technologies, LP | 11K | $176K | — | Held |
| Legal & General Group Plc | 10.7K | $171.7K | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 10.6K | $170.3K | — | Held |
| Aristides Capital LLC | 10.5K | $168K | — | Held |
| BLAIR WILLIAM & CO/IL | 10.2K | $163.3K | — | Held |
| AlphaCore Capital LLC | 10K | $160K | — | Held |
| MetLife Investment Management, LLC | 9.79K | $156.6K | — | Held |
| JPMORGAN CHASE & CO | 9.46K | $151.4K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 7.54K | $120.6K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 3.89K | $118.4K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 6.69K | $107.1K | — | Held |
| China Universal Asset Management Co., Ltd. | 5.1K | $81.6K | — | Held |
| NATIONAL BANK OF CANADA /FI/ | 4.85K | $77.3K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 4.6K | $73.6K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 4.13K | $66.2K | — | Held |
| Caitong International Asset Management Co., Ltd | 3.69K | $59K | — | Held |
| KLP KAPITALFORVALTNING AS | 3.1K | $49.6K | — | Held |
| OSAIC HOLDINGS, INC. | 2.1K | $33.6K | — | Held |
| State of Wyoming | 1.85K | $29.6K | — | Held |
| Tower Research Capital LLC (TRC) | 1.7K | $27.2K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 1.52K | $24.3K | — | Held |
| Ameritas Investment Partners, Inc. | 1.35K | $21.6K | — | Held |
| CIBC Private Wealth Group LLC | 1.15K | $18.3K | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.02M | $16.4K | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 869 | $13.9K | — | Held |
| BFSG, LLC | 635 | $10.2K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 607 | $9.71K | — | Held |
| C WorldWide Group Holding A/S | 500K | $8K | — | Held |
| Farther Finance Advisors, LLC | 496 | $7.94K | — | Held |
| FLAGSHIP HARBOR ADVISORS, LLC | 394 | $6.3K | — | New |
| Aster Capital Management (DIFC) Ltd | 323 | $5.17K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 267 | $4.27K | — | Held |
| GAMMA Investing LLC | 254 | $4.06K | — | Held |
| MassMutual Private Wealth & Trust, FSB | 245 | $3.92K | — | Held |
| Smartleaf Asset Management LLC | 189 | $3.05K | — | Held |
| GPS Wealth Strategies Group, LLC | 179 | $2.86K | — | Held |
| HRT FINANCIAL LP | 171.3K | $2.74K | — | Held |
| EverSource Wealth Advisors, LLC | 165 | $2.64K | — | Held |
| Optiver Holding B.V. | 142 | $2.27K | — | Held |
| Federation des caisses Desjardins du Quebec | 128 | $2.04K | — | Held |
| NewEdge Advisors, LLC | 110 | $1.76K | — | Held |
| Sterling Capital Management LLC | 109 | $1.74K | — | Held |
| SBI Securities Co., Ltd. | 82 | $1.31K | — | Held |
| Versant Capital Management, Inc | 80 | $1.28K | — | Held |
| ALGERT GLOBAL LLC | 76K | $1.22K | — | Held |
| HARBOR CAPITAL ADVISORS, INC. | 23.9K | $383 | — | Held |
| Allworth Financial LP | 20 | $320 | −$612 | Cut−$612 |
| State of Alaska, Department of Revenue | 19.2K | $306 | — | Held |
| Steward Partners Investment Advisory, LLC | 19 | $304 | — | Held |
| Ares Financial Consulting, LLC | 19 | $304 | — | Held |
| GSA CAPITAL PARTNERS LLP | 16.5K | $263 | — | Held |
| Sunbelt Securities, Inc. | 15 | $240 | — | Held |
| Larson Financial Group LLC | 13 | $208 | — | Held |
| Virtu Financial LLC | 12.3K | $198 | — | Held |
| SageView Advisory Group, LLC | 7 | $112 | — | Held |
| Stone House Investment Management, LLC | 5 | $80 | — | Held |
| Essential Partners LLC | 2 | $32 | — | New |
| ROTHSCHILD INVESTMENT LLC | 2 | $32 | — | Held |
| AMALGAMATED BANK | 508 | $8 | — | Held |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 312 | $5 | — | Held |
| CWM, LLC | 71 | $1 | — | Held |
| Daiwa Securities Group Inc. | 91 | $1 | — | Held |