| Point72 Asset Management, L.P. | 5.96M | $5.93M | — | Held |
| DAFNA Capital Management LLC | 2.79M | $2.78M | — | Held |
| Vanguard | 2.1M | $2.09M | — | Held |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.84M | $1.83M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 1.5M | $1.49M | — | Held |
| Spruce Street Capital LP | 1.42M | $1.41M | — | Held |
| Renaissance Technologies | 1.35M | $1.34M | — | Held |
| TWO SIGMA ADVISERS, LP | 1.27M | $1.26M | — | Held |
| Casdin Capital, LLC | 1.23M | $1.22M | — | Held |
| Syncona Portfolio Ltd | 1.21M | $1.21M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 610.4K | $607.2K | — | Held |
| BlackRock, Inc. | 601.9K | $598.7K | — | Held |
| SUPERSTRING CAPITAL MANAGEMENT LP | 463K | $460.6K | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 456.1K | $453.9K | — | Held |
| Citadel | 319.5K | $317.8K | — | Held |
| UBS Group AG | 214.5K | $213.4K | — | Held |
| State Street | 127.4K | $126.8K | — | Held |
| NORTHERN TRUST CORP | 105.1K | $104.5K | — | Held |
| RAYMOND JAMES FINANCIAL INC | 91.3K | $90.8K | — | Held |
| Fidelity | 71.5K | $71.2K | — | Held |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 77.8K | $70K | — | Held |
| PRUDENTIAL FINANCIAL INC | 59.8K | $59.5K | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 50.1K | $49.8K | — | Held |
| JANE STREET GROUP, LLC | 45.2K | $45K | — | Held |
| HarbourVest Partners LLC | 29K | $28.9K | — | Held |
| Parametrica Management Ltd | 27.8K | $27.7K | — | Held |
| XTX Topco Ltd | 15.3K | $15.3K | — | Held |
| Quadrant Private Wealth Management, LLC | 15.3K | $15.2K | — | Held |
| Scientech Research LLC | 12.4K | $12.3K | — | Held |
| Advisors Asset Management, Inc. | 8.31K | $8.27K | — | Held |
| JPMORGAN CHASE & CO | 3.08K | $3.06K | — | Held |
| SIMPLEX TRADING, LLC | 2.4K | $2.38K | — | Held |
| SBI Securities Co., Ltd. | 1.53K | $1.52K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 1.45K | $1.44K | — | Held |
| ACADIAN ASSET MANAGEMENT LLC | 1.22M | $1.21K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 883 | $878 | — | Held |
| BANK OF AMERICA CORP /DE/ | 525 | $522 | $260 | Added$224 |
| MARK SHEPTOFF FINANCIAL PLANNING, LLC | 500 | $497 | — | Held |
| GSA CAPITAL PARTNERS LLP | 333.2K | $331 | — | Held |
| Arax Advisory Partners | 99 | $98 | — | Held |
| ALGERT GLOBAL LLC | 76.8K | $76 | — | Held |
| WELLS FARGO & COMPANY/MN | 40 | $40 | — | Held |
| Optiver Holding B.V. | 32 | $32 | — | Held |
| CITIGROUP INC | 1 | $1 | — | Held |
| Smartleaf Asset Management LLC | 1 | $1 | — | Held |
| BARCLAYS PLC | 1 | $1 | $1 | Added$1 |
| ROYAL BANK OF CANADA | 69 | $0 | — | Held |