| Fidelity | 16.5M | $355.5M | — | Held |
| BlackRock, Inc. | 7.59M | $163.1M | — | Held |
| Point72 Asset Management, L.P. | 7.03M | $151.1M | — | Held |
| Vanguard | 6.04M | $129.7M | — | Held |
| Redmile Group, LLC | 5.72M | $122.8M | — | Held |
| ENAVATE SCIENCES GP, LLC | 4.77M | $102.4M | — | Held |
| PRIMECAP MANAGEMENT CO/CA/ | 4.69M | $100.6M | — | Held |
| State Street | 3.87M | $83.1M | — | Held |
| Driehaus Capital Management LLC | 3.71M | $79.6M | — | Held |
| JPMORGAN CHASE & CO | 2.86M | $61.3M | — | Held |
| EcoR1 Capital, LLC | 2.86M | $61.3M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 2.36M | $50.7M | — | Held |
| Jefferies Financial Group Inc. | 2M | $43M | — | Held |
| READYSTATE ASSET MANAGEMENT LP | 1.84M | $39.6M | — | Held |
| Citadel | 1.74M | $37.4M | — | Held |
| MORGAN STANLEY | 1.71M | $36.7M | $16.7M | Added$15.2M |
| Sofinnova Investments, Inc. | 1.62M | $34.8M | — | Held |
| Woodline Partners LP | 1.58M | $33.8M | — | Held |
| Balyasny Asset Management L.P. | 1.43M | $30.7M | — | Held |
| PRINCIPAL FINANCIAL GROUP INC | 1.4M | $30.2M | — | Held |
| SILVERARC CAPITAL MANAGEMENT, LLC | 1.13M | $24.2M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 934.5K | $20.1M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 840.7K | $18.1M | — | Held |
| JANUS HENDERSON GROUP PLC | 832.1K | $17.9M | — | Held |
| NORTHERN TRUST CORP | 828.7K | $17.8M | — | Held |
| Polar Capital Holdings Plc | 793.4K | $17M | — | Held |
| ExodusPoint Capital Management, LP | 779.6K | $16.7M | — | Held |
| TD Asset Management Inc | 759.2K | $16.3M | — | Held |
| GOLDMAN SACHS GROUP INC | 752.7K | $16.2M | — | Held |
| MARSHALL WACE, LLP | 737.1K | $15.8M | — | Held |
| Pivotal bioVenture Partners Investment Advisor LLC | 732.5K | $15.7M | — | Held |
| NAN FUNG TRINITY (HK) LTD | 714.6K | $15.3M | — | Held |
| Candriam S.C.A. | 539.9K | $11.6M | — | Held |
| Granahan Investment Management, LLC | 435.1K | $9.35M | — | Held |
| Rock Springs Capital Management LP | 347.7K | $7.47M | — | Held |
| Atika Capital Management LLC | 334.3K | $7.18M | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 316.4K | $6.8M | — | Held |
| UBS Group AG | 307.2K | $6.6M | — | Held |
| Alyeska Investment Group, L.P. | 293.8K | $6.31M | — | Held |
| KENNEDY CAPITAL MANAGEMENT LLC | 286.4K | $6.15M | — | Held |
| Parkman Healthcare Partners LLC | 277.8K | $5.97M | — | Held |
| Monashee Investment Management LLC | 274.9K | $5.9M | — | Held |
| Invesco Ltd. | 270.1K | $5.8M | — | Held |
| Bank of New York Mellon Corp | 263.4K | $5.66M | — | Held |
| BARCLAYS PLC | 246.1K | $5.29M | $2.04M | Added$2.84M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 237.3K | $5.03M | — | Held |
| BANK OF AMERICA CORP /DE/ | 202.7K | $4.35M | $900.4K | Added$3.28M |
| BURKEHILL GLOBAL MANAGEMENT, LP | 200K | $4.3M | — | Held |
| Neo Ivy Capital Management | 192.6K | $4.14M | — | Held |
| AMERIPRISE FINANCIAL INC | 190.6K | $4.09M | — | Held |
| Swiss National Bank | 185K | $3.97M | — | Held |
| Atom Investors LP | 175.8K | $3.78M | — | Held |
| GILDER GAGNON HOWE & CO LLC | 174.9K | $3.76M | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 170.9K | $3.67M | — | Held |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 170K | $3.65M | — | Held |
| Nuveen, LLC | 169.3K | $3.64M | — | Held |
| Trexquant Investment LP | 130.8K | $2.81M | — | Held |
| Birchview Capital, LP | 130K | $2.79M | — | Held |
| SummitTX Capital, L.P. | 127.6K | $2.74M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 123.7K | $2.66M | — | Held |
| RHUMBLINE ADVISERS | 113.6K | $2.44M | — | Held |
| Rafferty Asset Management, LLC | 113.4K | $2.44M | — | Held |
| WELLS FARGO & COMPANY/MN | 108.1K | $2.32M | — | Held |
| NEOS Investment Management LLC | 103.6K | $2.23M | — | Held |
| Longaeva Partners L.P. | 102.5K | $2.2M | — | Held |
| TEMA ETFS LLC | 102.1K | $2.19M | — | Held |
| LMR Partners LLP | 100K | $2.15M | — | Held |
| AMERICAN CENTURY COMPANIES INC | 98.1K | $2.11M | — | Held |
| Legal & General Group Plc | 95K | $2.04M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 93K | $2M | — | Held |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 82.6K | $1.77M | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 80.2K | $1.72M | — | Held |
| DEUTSCHE BANK AG\ | 76.2K | $1.64M | — | Held |
| Maven Securities LTD | 75K | $1.61M | — | Held |
| Verition Fund Management LLC | 72.9K | $1.57M | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 67K | $1.44M | — | Held |
| Freestone Capital Holdings, LLC | 61.5K | $1.32M | — | Held |
| DARK FOREST CAPITAL MANAGEMENT LP | 57.2K | $1.23M | — | Held |
| Erste Asset Management GmbH | 52K | $1.12M | — | Held |
| MetLife Investment Management, LLC | 52K | $1.12M | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 50.1K | $1.07M | — | Held |
| AlphaQuest LLC | 49K | $1.05M | — | Held |
| Baldwin Investment Management, LLC | 47.2K | $1.01M | — | Held |
| RAYMOND JAMES FINANCIAL INC | 46.6K | $1M | — | Held |
| Magnus Financial Group LLC | 45.8K | $982.9K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 45.7K | $982.6K | — | Held |
| SCHARF INVESTMENTS, LLC | 44.4K | $953.5K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 59.4K | $949.5K | — | Held |
| Susquehanna Portfolio Strategies, LLC | 44.2K | $948.6K | — | Held |
| Corient Private Wealth LLC | 43.2K | $928K | — | Held |
| Cerity Partners LLC | 42.8K | $919.2K | — | Held |
| PROFUND ADVISORS LLC | 42.7K | $917.2K | — | Held |
| Three Bridge Wealth Advisors, LLC | 37.6K | $808K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 35.4K | $761.1K | — | Held |
| Lido Advisors, LLC | 59.1K | $691.5K | — | Held |
| Schonfeld Strategic Advisors LLC | 32.1K | $689.5K | — | Held |
| Aquatic Capital Management LLC | 31.3K | $672.8K | — | Held |
| Palumbo Wealth Management LLC | 31K | $665.4K | — | Held |
| Squarepoint Ops LLC | 29.3K | $630.1K | — | Held |
| SEI INVESTMENTS CO | 27.7K | $595.4K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 27K | $580.3K | — | Held |
| ARIZONA STATE RETIREMENT SYSTEM | 26.1K | $560.7K | — | Held |
| PSP Research LLC | 25.2K | $542.3K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 24.3K | $520.9K | — | Held |
| Private Capital Advisors, Inc. | 23.5K | $505.6K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 23.5K | $504.8K | — | Held |
| SIMPLEX TRADING, LLC | 23.4K | $502.7K | — | Held |
| GROUP ONE TRADING LLC | 23K | $494K | — | Held |
| DIADEMA PARTNERS LP | 22.5K | $483.3K | — | Held |
| Creative Planning | 20.9K | $448.5K | — | Held |
| CITIZENS FINANCIAL GROUP INC/RI | 20K | $429.6K | — | Held |
| Sequoia Financial Advisors, LLC | 19.1K | $410.8K | — | Held |
| MILLENNIUM MANAGEMENT LLC | 18.8K | $403.7K | — | Held |
| Laird Norton Wetherby Trust Company, LLC | 18.5K | $397.4K | — | Held |
| XTX Topco Ltd | 17.8K | $382.4K | — | Held |
| ProShare Advisors LLC | 17.1K | $367.8K | — | Held |
| CITIGROUP INC | 16.5K | $353.5K | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 16.4K | $352.7K | — | Held |
| KLP KAPITALFORVALTNING AS | 15K | $322.2K | — | Held |
| Pictet Asset Management Holding SA | 14.6K | $314K | — | Held |
| Dynamic Technology Lab Private Ltd | 14K | $301K | — | Held |
| Cetera Investment Advisers | 14K | $300.8K | — | Held |
| Virtus Investment Advisers, LLC | 13.6K | $292K | — | Held |
| T. Rowe Price Investment Management, Inc. | 13.4M | $288.3K | — | Held |
| T3 Companies, LLC | 12.3K | $264.2K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 11.1K | $239.1K | — | Held |
| Sterling Investment Advisors, Ltd. | 11.1K | $237.7K | — | Held |
| HighTower Advisors, LLC | 11K | $236.9K | — | Held |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 10.6K | $227.8K | — | Held |
| VICTORY CAPITAL MANAGEMENT INC | 10.3K | $220.7K | — | Held |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 10.1K | $217.7K | — | Held |
| Gotham Asset Management, LLC | 10.1K | $216.9K | — | Held |
| Velan Capital Investment Management LP | 10K | $214.8K | — | Held |
| Sandia Investment Management LP | 10K | $214.8K | — | Held |
| ANTIPODES PARTNERS Ltd | 8.83K | $189.8K | — | Held |
| Persistent Asset Partners Ltd | 8.53K | $183.2K | — | New |
| Ensign Peak Advisors, Inc | 7.7K | $165.4K | — | Held |
| Ameritas Investment Partners, Inc. | 7.61K | $163.4K | — | Held |
| Russell Investments Group, Ltd. | 7.42K | $159.3K | — | Held |
| Aster Capital Management (DIFC) Ltd | 5.63K | $120.9K | — | Held |
| Caption Management, LLC | 5.3K | $113.8K | — | Held |
| ROYAL BANK OF CANADA | 4.1K | $88K | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.38M | $72.6K | — | Held |
| ASSETMARK, INC | 3.09K | $66.4K | — | Held |
| STRS OHIO | 3K | $64.4K | — | Held |
| MB, LEVIS & ASSOCIATES, LLC | 2.37K | $51K | — | Held |
| OSAIC HOLDINGS, INC. | 1.51K | $32.5K | — | Held |
| GAMMA Investing LLC | 1.38K | $29.6K | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 1.32K | $28.4K | — | Held |
| Allworth Financial LP | 1.16K | $25K | $11K | Added$11.8K |
| Tower Research Capital LLC (TRC) | 957 | $20.6K | — | Held |
| ORG Partners LLC | 880 | $18.9K | — | Held |
| PNC Financial Services Group, Inc. | 860 | $18.5K | — | Held |
| Caitong International Asset Management Co., Ltd | 744 | $16K | — | Held |
| Sterling Capital Management LLC | 612 | $13.1K | — | Held |
| Optiver Holding B.V. | 410 | $8.81K | — | Held |
| SIGNATUREFD, LLC | 204 | $4.38K | — | Held |
| ROTHSCHILD INVESTMENT LLC | 200 | $4.3K | — | Held |
| Steigerwald, Gordon & Koch Inc. | 200 | $4.3K | — | Held |
| NATIONAL BANK OF CANADA /FI/ | 187 | $4.02K | — | Held |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 182.4K | $3.92K | — | Held |
| SG Americas Securities, LLC | 162.2K | $3.48K | — | Held |
| Basepoint Wealth LLC | 91 | $1.95K | — | Held |
| Larson Financial Group LLC | 83 | $1.78K | — | Held |
| Parkside Financial Bank & Trust | 75 | $1.61K | — | Held |
| Fortitude Family Office, LLC | 60 | $1.29K | — | Held |
| CIBC Private Wealth Group LLC | 32 | $687 | — | Held |
| Rachor Investment Advisory Services, LLC | 29 | $623 | — | Held |
| Keating Financial Advisory Services, Inc. | 26 | $558 | — | Held |
| Pinnacle Wealth Planning Services, Inc. | 23 | $494 | — | Held |
| Bear Mountain Capital, Inc. | 20 | $457 | — | Held |
| HARBOR CAPITAL ADVISORS, INC. | 19.9K | $426 | — | Held |
| Arax Advisory Partners | 19 | $408 | — | Held |
| True Wealth Design, LLC | 18 | $387 | — | Held |
| Farther Finance Advisors, LLC | 15 | $322 | — | Held |
| SBI Securities Co., Ltd. | 9 | $193 | — | Held |
| Cygnus Capital Advisors, LLC | 7.99K | $172 | — | Held |
| IFP Advisors, Inc | 6 | $129 | $59 | Added$59 |
| MassMutual Private Wealth & Trust, FSB | 5 | $107 | — | Held |
| AMALGAMATED BANK | 2.94K | $63 | — | Held |
| CWM, LLC | 342 | $7 | — | Held |
| FNY Investment Advisers, LLC | 50 | $1 | — | New |