| EcoR1 Capital, LLC | 2.23M | $4.3M | — | Held |
| Affinity Asset Advisors, LLC | 2.06M | $3.97M | — | Held |
| Logos Global Management LP | 2M | $3.86M | — | Held |
| Frazier Life Sciences Management, L.P. | 1.95M | $3.77M | — | Held |
| Balyasny Asset Management L.P. | 1.1M | $2.12M | — | Held |
| Ikarian Capital, LLC | 957.1K | $1.85M | — | Held |
| Vanguard | 883.1K | $1.7M | — | Held |
| Sio Capital Management, LLC | 740K | $1.43M | — | Held |
| AMERIPRISE FINANCIAL INC | 584.4K | $1.13M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 456.3K | $880.7K | — | Held |
| ADAR1 Capital Management, LLC | 405.5K | $782.7K | — | Held |
| Renaissance Technologies | 353.3K | $681.9K | — | Held |
| Monashee Investment Management LLC | 274.9K | $530.5K | — | Held |
| BOOTHBAY FUND MANAGEMENT, LLC | 254.4K | $491K | — | Held |
| Hudson Bay Capital Management LP | 242.1K | $467.2K | — | New |
| NOESIS CAPITAL MANGEMENT CORP | 224.2K | $432.7K | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 222.6K | $429.6K | — | Held |
| Walleye Capital LLC | 198.4K | $382.9K | — | Held |
| Jefferies Financial Group Inc. | 160K | $308.8K | — | Held |
| UBS Group AG | 126.6K | $244.3K | — | Held |
| MARSHALL WACE, LLP | 121.3K | $234.1K | — | Held |
| BANK OF AMERICA CORP /DE/ | 115.8K | $223.5K | $160 | Added$223.4K |
| TWO SIGMA ADVISERS, LP | 108.4K | $209.2K | — | Held |
| SILVERARC CAPITAL MANAGEMENT, LLC | 106K | $204.6K | — | Held |
| JANE STREET GROUP, LLC | 105.7K | $204K | — | Held |
| Mountain Capital Investment Advisors Inc. | 63K | $141.8K | — | Held |
| State Street | 72.9K | $140.7K | — | Held |
| BlackRock, Inc. | 42.7K | $82.5K | — | Held |
| NORTHERN TRUST CORP | 40.3K | $77.8K | — | Held |
| Persistent Asset Partners Ltd | 39.6K | $76.4K | — | New |
| XTX Topco Ltd | 37K | $71.4K | — | Held |
| MORGAN STANLEY | 27.6K | $53.3K | $63 | Added$53.2K |
| PFG Investments, LLC | 21.5K | $41.5K | — | Held |
| Vanguard Personalized Indexing Management, LLC | 12.5K | $24.1K | — | Held |
| CITIGROUP INC | 5.05K | $9.74K | — | Held |
| Tower Research Capital LLC (TRC) | 1.38K | $2.66K | — | Held |
| Fortitude Family Office, LLC | 431 | $832 | — | Held |
| OSAIC HOLDINGS, INC. | 384 | $741 | — | Held |
| SHP Wealth Management | 60 | $116 | — | Held |
| Arax Advisory Partners | 91 | $112 | — | Held |
| SBI Securities Co., Ltd. | 22 | $42 | — | Held |
| SOA Wealth Advisors, LLC. | 13 | $25 | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 5 | $10 | — | Held |
| Activest Wealth Management | 4 | $8 | — | Held |
| JPMORGAN CHASE & CO | 2 | $4 | — | Held |
| Financial Gravity Asset Management, Inc. | 2 | $4 | — | Held |
| BARCLAYS PLC | 2 | $4 | — | New |
| WELLS FARGO & COMPANY/MN | 1 | $2 | — | Held |
| Steward Partners Investment Advisory, LLC | 1 | $2 | — | Held |
| Motiv8 Investments LLC | 1 | $0 | — | Held |