| SR One Capital Management, LP | 6.53M | $61.2M | — | Held |
| Point72 Asset Management, L.P. | 5.37M | $50.4M | — | Held |
| Logos Global Management LP | 2.5M | $23.4M | — | Held |
| BAKER BROS. ADVISORS LP | 2.23M | $20.9M | — | Held |
| BlackRock, Inc. | 2.12M | $19.9M | — | Held |
| Vanguard | 1.63M | $15.3M | — | Held |
| Vivo Capital, LLC | 1.61M | $15.1M | — | Held |
| Almitas Capital LLC | 1.53M | $14.4M | — | Held |
| RA CAPITAL MANAGEMENT, L.P. | 1.46M | $13.7M | — | Held |
| Driehaus Capital Management LLC | 1.18M | $11.1M | — | Held |
| Woodline Partners LP | 944K | $8.86M | — | Held |
| Kynam Capital Management, LP | 784.6K | $7.36M | — | Held |
| Fidelity | 771.3K | $7.23M | — | Held |
| MORGAN STANLEY | 702.3K | $6.59M | $325.6K | Added$5.26M |
| GEODE CAPITAL MANAGEMENT, LLC | 679.6K | $6.38M | — | Held |
| State Street | 647.6K | $6.07M | — | Held |
| Frazier Life Sciences Management, L.P. | 521K | $4.89M | — | Held |
| Citadel | 459.9K | $4.31M | — | Held |
| D. E. Shaw & Co., Inc. | 438.9K | $4.12M | — | Held |
| Invesco Ltd. | 305.8K | $2.87M | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 297.9K | $2.8M | — | Held |
| Renaissance Technologies | 287.1K | $2.69M | — | Held |
| NORTHERN TRUST CORP | 286.6K | $2.69M | — | Held |
| GOLDMAN SACHS GROUP INC | 270.7K | $2.54M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 236.9K | $2.22M | — | Held |
| JANE STREET GROUP, LLC | 226.5K | $2.12M | — | Held |
| MARSHALL WACE, LLP | 225.5K | $2.12M | — | Held |
| Elmind Capital, LP | 207.9K | $1.95M | — | Held |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 194.6K | $1.83M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 180.9K | $1.7M | — | Held |
| AMERIPRISE FINANCIAL INC | 158.4K | $1.49M | — | Held |
| ACUTA CAPITAL PARTNERS, LLC | 150.9K | $1.42M | — | Held |
| Nuveen, LLC | 125.3K | $1.17M | — | Held |
| RAYMOND JAMES FINANCIAL INC | 109.8K | $1.03M | — | Held |
| DIADEMA PARTNERS LP | 100.3K | $941K | — | Held |
| Trexquant Investment LP | 100K | $937.7K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 94.8K | $889.5K | — | Held |
| BARCLAYS PLC | 87.1K | $816.6K | $161.1K | Added$152.7K |
| Bank of New York Mellon Corp | 85K | $797.1K | — | Held |
| Informed Momentum Co LLC | 78.9K | $740.5K | — | Held |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 78.5K | $736.3K | — | Held |
| Lynx1 Capital Management LP | 69.5K | $652.1K | — | Held |
| Palumbo Wealth Management LLC | 69.4K | $650.8K | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 61.9K | $580.2K | — | Held |
| AMERICAN CENTURY COMPANIES INC | 57.8K | $542.1K | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 54.6K | $512.1K | — | Held |
| SEI INVESTMENTS CO | 52.7K | $494.6K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 50.7K | $475.2K | — | Held |
| KENNEDY CAPITAL MANAGEMENT LLC | 50K | $469.2K | — | Held |
| ALPS ADVISORS INC | 46.8K | $438.7K | — | Held |
| TWO SIGMA INVESTMENTS, LP | 46.2K | $433.7K | — | Held |
| Squarepoint Ops LLC | 46.1K | $432.8K | — | Held |
| ALLIANCEBERNSTEIN L.P. | 46.1K | $432.6K | — | Held |
| PRUDENTIAL FINANCIAL INC | 42.7K | $400.6K | — | Held |
| XTX Topco Ltd | 35.3K | $331K | — | Held |
| Persistent Asset Partners Ltd | 35K | $328.2K | — | New |
| RHUMBLINE ADVISERS | 34.8K | $326.2K | — | Held |
| China Universal Asset Management Co., Ltd. | 34.3K | $321.6K | — | Held |
| BANK OF AMERICA CORP /DE/ | 27.4K | $257.4K | $44.2K | Added$77.4K |
| Corient Private Wealth LLC | 27K | $252.9K | — | Held |
| WELLS FARGO & COMPANY/MN | 26.8K | $251.3K | — | Held |
| UBS Group AG | 25.5K | $239.5K | — | Held |
| TWO SIGMA ADVISERS, LP | 25.3K | $237.3K | — | Held |
| Russell Investments Group, Ltd. | 25.2K | $236.7K | — | Held |
| STRS OHIO | 25.2K | $236.4K | — | Held |
| AlphaCentric Advisors LLC | 20.3K | $190.1K | — | Held |
| Baader Bank Aktiengesellschaft | 20K | $187.6K | — | Held |
| Velan Capital Investment Management LP | 20K | $187.6K | — | Held |
| 9823 Capital, L.P. | 19.2K | $180.1K | — | Held |
| DEUTSCHE BANK AG\ | 15.5K | $145.8K | — | Held |
| MetLife Investment Management, LLC | 15.2K | $143K | — | Held |
| JPMORGAN CHASE & CO | 14.5K | $135.6K | — | Held |
| Engineers Gate Manager LP | 14K | $131.4K | — | Held |
| Icahn Capital | 13.7K | $128.8K | — | Held |
| Mariner, LLC | 12.8K | $120K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 11.8K | $110.9K | — | Held |
| AXQ CAPITAL, LP | 11.7K | $110K | — | Held |
| TWO SIGMA SECURITIES, LLC | 11.4K | $106.9K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 11.1K | $104K | — | Held |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 7.09K | $66.5K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 6.6K | $61.9K | — | Held |
| Tower Research Capital LLC (TRC) | 4.27K | $40.1K | — | Held |
| CAZ INVESTMENTS LP | 3.5K | $32.8K | — | Held |
| CITIGROUP INC | 3.11K | $29.2K | — | Held |
| Torren Management, LLC | 2.82K | $26.5K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 2.77K | $26K | — | Held |
| Ameritas Investment Partners, Inc. | 2.57K | $24.1K | — | Held |
| Legal & General Group Plc | 2.08K | $19.5K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 2.03K | $19K | — | Held |
| PNC Financial Services Group, Inc. | 1.82K | $17K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1.47K | $13.8K | — | Held |
| Sterling Capital Management LLC | 1.38K | $12.9K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1.23K | $11.5K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 1.12K | $10.5K | — | Held |
| GAMMA Investing LLC | 750 | $7.04K | — | Held |
| Rockefeller Capital Management L.P. | 738 | $6.92K | — | Held |
| ROYAL BANK OF CANADA | 638 | $6K | — | Held |
| ACADIAN ASSET MANAGEMENT LLC | 612.8K | $5.74K | — | Held |
| Clearstead Advisors, LLC | 610 | $5.72K | — | Held |
| Private Wealth Management Group, LLC | 558 | $5.24K | — | Held |
| Farther Finance Advisors, LLC | 385 | $3.61K | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 380 | $3.56K | — | Held |
| Optiver Holding B.V. | 328 | $3.08K | — | Held |
| Physician Wealth Advisors, Inc. | 268 | $2.51K | — | Held |
| MassMutual Private Wealth & Trust, FSB | 239 | $2.24K | — | Held |
| ALGERT GLOBAL LLC | 187.8K | $1.76K | — | Held |
| Arax Advisory Partners | 47 | $441 | — | Held |
| Virtu Financial LLC | 22.7K | $212 | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 15.7K | $148 | — | Held |
| OSAIC HOLDINGS, INC. | 10 | $94 | — | Held |
| Larson Financial Group LLC | 3 | $28 | — | Held |
| EverSource Wealth Advisors, LLC | 3 | $28 | — | Held |
| True Wealth Design, LLC | 1 | $10 | — | Held |
| AMALGAMATED BANK | 751 | $7 | — | Held |
| CWM, LLC | 239 | $2 | — | Held |
| Daiwa Securities Group Inc. | 100 | $1 | — | Held |
| Capital Advisors, Ltd. LLC | 12 | $0 | — | Held |