| EcoR1 Capital, LLC | 7.88M | $382M | — | Held |
| Point72 Asset Management, L.P. | 1.93M | $93.7M | — | Held |
| BlackRock, Inc. | 1.73M | $84.1M | — | Held |
| Vanguard | 1.54M | $74.9M | — | Held |
| TANG CAPITAL MANAGEMENT LLC | 1.33M | $64.6M | — | Held |
| State Street | 1.05M | $51.1M | — | Held |
| MORGAN STANLEY | 1.03M | $50.2M | $18.5M | Added$2.5M |
| Sanofi | 821.9K | $39.8M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 813.6K | $39.4M | — | Held |
| Palo Alto Investors LP | 690K | $33.5M | — | Held |
| D. E. Shaw & Co., Inc. | 670.3K | $32.5M | — | Held |
| 683 Capital Management, LLC | 648.1K | $31.4M | — | Held |
| First Light Asset Management, LLC | 646.2K | $31.3M | — | Held |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 559.7K | $27.1M | — | Held |
| Woodline Partners LP | 501K | $24.3M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 469.5K | $22.8M | — | Held |
| Affinity Asset Advisors, LLC | 444.7K | $21.6M | — | Held |
| GOLDMAN SACHS GROUP INC | 398.9K | $19.3M | — | Held |
| TWO SIGMA ADVISERS, LP | 356.7K | $17.3M | — | Held |
| Nuveen, LLC | 316.7K | $15.4M | — | Held |
| FEDERATED HERMES, INC. | 299.4K | $14.5M | — | Held |
| Sofinnova Investments, Inc. | 287.7K | $13.9M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 256.6K | $12.4M | — | Held |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 229.1K | $11.1M | — | Held |
| Ensign Peak Advisors, Inc | 215.5K | $10.4M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 198.7K | $9.63M | — | Held |
| NORTHERN TRUST CORP | 181.9K | $8.82M | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 164.8K | $7.99M | — | Held |
| Squarepoint Ops LLC | 160.7K | $7.79M | — | Held |
| Soleus Capital Management, L.P. | 135K | $6.54M | — | Held |
| BANK OF AMERICA CORP /DE/ | 130.8K | $6.34M | $2.27M | Added$2.44M |
| Granahan Investment Management, LLC | 125.9K | $6.1M | — | Held |
| Invesco Ltd. | 124K | $6.01M | — | Held |
| Connor, Clark & Lunn Investment Management Ltd. | 122.5K | $5.94M | — | Held |
| Eversept Partners, LP | 120.9K | $5.86M | — | Held |
| Jump Financial, LLC | 120.2K | $5.83M | — | Held |
| VICTORY CAPITAL MANAGEMENT INC | 110.6K | $5.36M | — | Held |
| Citadel | 109.5K | $5.31M | — | Held |
| Qube Research & Technologies Ltd | 109K | $5.28M | — | Held |
| HighMark Wealth Management LLC | 94K | $4.56M | — | Held |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 93.7K | $4.54M | — | Held |
| JANE STREET GROUP, LLC | 84.4K | $4.09M | — | Held |
| ExodusPoint Capital Management, LP | 83.3K | $4.04M | — | Held |
| Renaissance Technologies | 76.3K | $3.7M | — | Held |
| CITIGROUP INC | 73.5K | $3.56M | — | Held |
| UBS Group AG | 70K | $3.4M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 61.2K | $2.97M | — | Held |
| BARCLAYS PLC | 59.7K | $2.89M | $1.07M | Added$949.1K |
| Trexquant Investment LP | 58.8K | $2.85M | — | Held |
| Fisher Asset Management, LLC | 56.6K | $2.74M | — | Held |
| Bank of New York Mellon Corp | 55.3K | $2.68M | — | Held |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 55.1K | $2.67M | — | Held |
| Moody Aldrich Partners LLC | 47.6K | $2.31M | — | Held |
| Bleakley Financial Group, LLC | 43.5K | $2.11M | — | Held |
| PDT Partners, LLC | 43K | $2.08M | — | Held |
| CREDIT AGRICOLE S A | 40K | $1.94M | — | Held |
| XTX Topco Ltd | 38.6K | $1.87M | — | Held |
| Susquehanna Portfolio Strategies, LLC | 35.9K | $1.74M | — | Held |
| Rafferty Asset Management, LLC | 35.3K | $1.71M | — | Held |
| DCF Advisers, LLC | 35.3K | $1.71M | — | Held |
| Y-Intercept (Hong Kong) Ltd | 33.1K | $1.6M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 30.5K | $1.48M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 30.5K | $1.48M | — | Held |
| OSAIC HOLDINGS, INC. | 27.7K | $1.34M | — | Held |
| Swiss National Bank | 27.6K | $1.34M | — | Held |
| Fidelity | 27.1K | $1.31M | — | Held |
| Icahn Capital | 26.3K | $1.28M | — | Held |
| Campbell & CO Investment Adviser LLC | 25.4K | $1.23M | — | Held |
| Headlands Technologies LLC | 25.3K | $1.23M | — | Held |
| RHUMBLINE ADVISERS | 25K | $1.21M | — | Held |
| Schonfeld Strategic Advisors LLC | 24.4K | $1.18M | — | Held |
| Quadrature Capital Ltd | 24.3K | $1.18M | — | Held |
| MACKENZIE FINANCIAL CORP | 24.2K | $1.17M | — | Held |
| NEOS Investment Management LLC | 22.9K | $1.11M | — | Held |
| TEMA ETFS LLC | 22.6K | $1.09M | — | Held |
| WELLS FARGO & COMPANY/MN | 22.2K | $1.08M | — | Held |
| PANAGORA ASSET MANAGEMENT INC | 20.9K | $1.01M | — | Held |
| Russell Investments Group, Ltd. | 19.7K | $955.8K | — | Held |
| Legal & General Group Plc | 18.2K | $881.4K | — | Held |
| TUDOR INVESTMENT CORP ET AL | 17.3K | $838.9K | $247.7K | Added$414.3K |
| Creative Planning | 15.3K | $739.5K | — | Held |
| Cresset Asset Management, LLC | 15.1K | $733.1K | $270.1K | Added$250.7K |
| Orion Porfolio Solutions, LLC | 14.7K | $712.5K | — | Held |
| DEUTSCHE BANK AG\ | 14.4K | $697.2K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 14.1K | $685.4K | — | Held |
| PROFUND ADVISORS LLC | 13.1K | $634.5K | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 12.8K | $618.6K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 15.1K | $550.7K | — | Held |
| JPMORGAN CHASE & CO | 10.9K | $529.2K | — | Held |
| Engineers Gate Manager LP | 10.9K | $527.5K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 10.6K | $515.4K | — | Held |
| MetLife Investment Management, LLC | 10.3K | $500.7K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9.29K | $450.2K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 9.09K | $440.6K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 8.96K | $434.1K | — | Held |
| Bridgefront Capital, LLC | 8.55K | $414.5K | — | Held |
| Entropy Technologies, LP | 8.3K | $402.4K | — | Held |
| Blueshift Asset Management, LLC | 7.85K | $380.7K | — | Held |
| AlphaQuest LLC | 7.76K | $376.3K | — | Held |
| China Universal Asset Management Co., Ltd. | 7.51K | $364.2K | — | Held |
| JANUS HENDERSON GROUP PLC | 7.46K | $362.2K | — | Held |
| GLENMEDE TRUST CO NA | 7.35K | $356.1K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 6.92K | $335.6K | — | Held |
| SummitTX Capital, L.P. | 6.53K | $316.5K | — | Held |
| Duncan Williams Asset Management, LLC | 6.53K | $315.7K | — | Held |
| Quantinno Capital Management LP | 6.43K | $311.9K | — | Held |
| Savant Capital, LLC | 6.29K | $305.2K | — | New |
| ENVESTNET ASSET MANAGEMENT INC | 6.1K | $295.6K | — | Held |
| Virtus Investment Advisers, LLC | 5.92K | $287K | — | Held |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 5.85K | $283.6K | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 5.68K | $275.5K | — | Held |
| Ascent Group, LLC | 5.66K | $274.5K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 5.64K | $273.5K | — | Held |
| FMB WEALTH MANAGEMENT | 5.59K | $271.1K | — | Held |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 5.53K | $267.9K | — | Held |
| SEI INVESTMENTS CO | 4.97K | $240.8K | — | Held |
| ProShare Advisors LLC | 4.6K | $222.9K | — | Held |
| nVerses Capital, LLC | 4.44K | $215.2K | — | Held |
| Latash Investments, LLC | 4.39K | $213K | — | Held |
| Aquatic Capital Management LLC | 3.17K | $153.9K | — | Held |
| KLP KAPITALFORVALTNING AS | 3K | $145.4K | — | Held |
| SBI Securities Co., Ltd. | 1.83K | $88.9K | — | Held |
| ROYAL BANK OF CANADA | 1.72K | $83K | — | Held |
| Ameritas Investment Partners, Inc. | 1.65K | $79.8K | — | Held |
| US BANCORP \DE\ | 1.64K | $79.6K | — | Held |
| Larson Financial Group LLC | 1.62K | $78.7K | — | Held |
| Caitong International Asset Management Co., Ltd | 1.53K | $74.2K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 1.34K | $65.2K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 963 | $46.7K | — | Held |
| EverSource Wealth Advisors, LLC | 875 | $42.4K | — | Held |
| Smartleaf Asset Management LLC | 835 | $40.3K | — | Held |
| Tower Research Capital LLC (TRC) | 727 | $35.2K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 543 | $26.3K | — | Held |
| Versant Capital Management, Inc | 454 | $22K | — | Held |
| Farther Finance Advisors, LLC | 384 | $18.6K | — | Held |
| GAMMA Investing LLC | 384 | $18.6K | — | Held |
| SIGNATUREFD, LLC | 352 | $17.1K | — | Held |
| Pinnacle Wealth Planning Services, Inc. | 334 | $16.2K | — | Held |
| WHITTIER TRUST CO | 224 | $9.84K | — | Held |
| QUADRANT CAPITAL GROUP LLC | 175 | $8.48K | — | Held |
| ROTHSCHILD INVESTMENT LLC | 165 | $8K | — | Held |
| Allworth Financial LP | 143 | $6.93K | $2.55K | Cut−$13.6K |
| Aster Capital Management (DIFC) Ltd | 125 | $6.06K | — | Held |
| HRT FINANCIAL LP | 122.6K | $5.94K | — | Held |
| Sterling Capital Management LLC | 116 | $5.62K | — | Held |
| PNC Financial Services Group, Inc. | 104 | $5.04K | — | Held |
| Physician Wealth Advisors, Inc. | 85 | $4.12K | — | Held |
| Rockefeller Capital Management L.P. | 65 | $3.15K | — | Held |
| Penserra Capital Management LLC | 56.4K | $2.73K | — | Held |
| Parallel Advisors, LLC | 55 | $2.67K | — | Held |
| Optiver Holding B.V. | 54 | $2.62K | — | Held |
| Steward Partners Investment Advisory, LLC | 43 | $2.08K | — | Held |
| ASSETMARK, INC | 36 | $1.75K | — | Held |
| Essential Partners LLC | 33 | $1.6K | $590 | Added$590 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 26K | $1.26K | — | Held |
| Parkside Financial Bank & Trust | 25 | $1.21K | — | Held |
| Blue Trust, Inc. | 19 | $921 | — | Held |
| ALGERT GLOBAL LLC | 16.4K | $795 | — | Held |
| Stone House Investment Management, LLC | 13 | $630 | — | Held |
| MassMutual Private Wealth & Trust, FSB | 12 | $582 | — | Held |
| GSA CAPITAL PARTNERS LLP | 10.7K | $518 | — | Held |
| SG Americas Securities, LLC | 10.4K | $506 | — | Held |
| MAI Capital Management | 10 | $485 | — | Held |
| Arax Advisory Partners | 8 | $388 | — | Held |
| ACADIAN ASSET MANAGEMENT LLC | 5.81K | $280 | — | Held |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 4.86K | $236 | — | Held |
| True Wealth Design, LLC | 4 | $194 | — | Held |
| Sunbelt Securities, Inc. | 4 | $194 | — | Held |
| BESSEMER GROUP INC | 1.46K | $71 | — | Held |
| TFC Financial Management, Inc. | 1 | $49 | — | Held |
| CWM, LLC | 1.01K | $49 | — | Held |
| IFP Advisors, Inc | 1 | $48 | $17 | Added$17 |
| CIBC Private Wealth Group LLC | 1 | $48 | — | Held |
| CANADA LIFE ASSURANCE Co | 750 | $36 | — | Held |
| AMALGAMATED BANK | 580 | $28 | — | Held |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 238 | $12 | — | Held |
| Daiwa Securities Group Inc. | 75 | $4 | — | Held |
| Covestor Ltd | 5 | $0 | — | Held |