| ORBIMED ADVISORS LLC | 3.06M | $1.75M | −$276.6K | Cut−$276.6K |
| TCG Crossover Management, LLC | 2.68M | $1.53M | −$242K | Cut−$242K |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.57M | $900.4K | — | Held |
| ADAR1 Capital Management, LLC | 751.1K | $429.3K | −$56.4K | Added$16.5K |
| Ikarian Capital, LLC | 519.1K | $296.7K | −$46.9K | Cut−$46.9K |
| TWO SIGMA INVESTMENTS, LP | 469.6K | $268.4K | −$17.7K | Added$138.9K |
| GEODE CAPITAL MANAGEMENT, LLC | 453.4K | $259.2K | −$31.9K | Added$25.6K |
| BlackRock, Inc. | 448.5K | $256.3K | −$38.2K | Cut−$23.5K |
| MILLENNIUM MANAGEMENT LLC | 430.4K | $246K | −$17.8K | Added$115.6K |
| LUMINUS MANAGEMENT LLC | 396.1K | $226.3K | −$31.6K | Cut−$5.32K |
| Renaissance Technologies | 291.3K | $166.5K | −$14.5K | Added$60K |
| AdvisorShares Investments LLC | 277.1K | $158.4K | −$22.6K | Cut−$7.23K |
| JANE STREET GROUP, LLC | 272.8K | $155.9K | −$24.7K | Cut−$193K |
| VANGUARD FIDUCIARY TRUST CO | 217.7K | $124.5K | — | Held |
| Verdad Advisers, LP | 184.9K | $105.7K | — | New |
| XTX Topco Ltd | 152.8K | $87.4K | — | New |
| Shay Capital LLC | 144.5K | $82.6K | — | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 142.6K | $81.5K | −$12.9K | Cut−$140.1K |
| BOOTHBAY FUND MANAGEMENT, LLC | 134.6K | $76.9K | −$12.2K | Cut−$12.2K |
| State Street | 121.1K | $69.2K | −$10.9K | Cut−$10.9K |
| TUDOR INVESTMENT CORP ET AL | 106.2K | $60.7K | −$6.89K | Added$10.3K |
| DIADEMA PARTNERS LP | 105.4K | $60.3K | −$9.04K | Cut−$5.94K |
| STEMPOINT CAPITAL LP | 616.7K | $58.2K | −$83.9K | Cut−$83.9K |
| SIMPLEX TRADING, LLC | 89.6K | $51.3K | — | New |
| UBS Group AG | 78.7K | $45K | −$4.68K | Added$10.6K |
| NORTHERN TRUST CORP | 72.7K | $41.5K | −$6.57K | Cut−$6.57K |
| PRUDENTIAL FINANCIAL INC | 53.1K | $30.3K | — | New |
| Persistent Asset Partners Ltd | 26.6K | $15.2K | −$2.4K | Cut−$2.4K |
| Schonfeld Strategic Advisors LLC | 26.6K | $15.2K | −$1.97K | Added$808 |
| Kestra Advisory Services, LLC | 26K | $14.9K | −$2.35K | Cut−$2.37K |
| HighTower Advisors, LLC | 20.6K | $11.8K | −$1.87K | Cut−$1.86K |
| GROUP ONE TRADING LLC | 19.9K | $11.4K | −$1.8K | Cut−$58.9K |
| Truvestments Capital LLC | 17K | $9.71K | −$1.54K | Cut−$1.54K |
| TWO SIGMA SECURITIES, LLC | 16.5K | $9.43K | — | New |
| StoneX Group Inc. | 15.2K | $8.69K | −$1.21K | Cut−$150 |
| RAYMOND JAMES FINANCIAL INC | 14.9K | $8.51K | — | New |
| Caption Management, LLC | 14.7K | $8.38K | −$1.33K | Cut−$2.72K |
| Vanguard Global Advisers, LLC | 10.8K | $6.18K | — | Held |
| Performa Ltd (US), LLC | 7.5K | $4.29K | −$91 | Added$3.62K |
| OSAIC HOLDINGS, INC. | 4.13K | $2.36K | −$374 | Cut−$1.13K |
| ROYAL BANK OF CANADA | 2.13K | $1K | — | New |
| Tower Research Capital LLC (TRC) | 1.57K | $898 | −$143 | Cut−$4.77K |
| Annis Gardner Whiting Capital Advisors, LLC | 600 | $343 | — | New |
| ACADIAN ASSET MANAGEMENT LLC | 589.7K | $336 | — | New |
| CWM, LLC | 582 | $333 | $333 | Added$333 |
| MAI Capital Management | 526 | $301 | −$48 | Cut−$48 |
| SBI Securities Co., Ltd. | 288 | $165 | −$26 | Cut−$26 |
| JONES FINANCIAL COMPANIES LLLP | 114 | $65 | −$10 | Cut−$10 |
| GSA CAPITAL PARTNERS LLP | 49.8K | $28 | — | New |
| Fairman Group, LLC | 29 | $17 | −$2 | Cut−$2 |
| HRT FINANCIAL LP | 25.4K | $14 | −$2 | Cut−$10 |
| JPMORGAN CHASE & CO | 16 | $9 | −$2 | Cut−$2 |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 16 | $9 | — | New |
| BNP PARIBAS FINANCIAL MARKETS | 13 | $7 | −$2 | Cut−$2 |
| MORGAN STANLEY | 1 | $1 | $0 | Cut−$8.38K |
| CITIGROUP INC | 1 | $1 | — | New |