| ORBIMED ADVISORS LLC | 3.06M | $2.03M | — | Held |
| TCG Crossover Management, LLC | 2.68M | $1.77M | — | Held |
| Vanguard | 1.82M | $1.21M | — | Held |
| ADAR1 Capital Management, LLC | 623.6K | $412.7K | — | Held |
| JANE STREET GROUP, LLC | 527.1K | $348.9K | — | Held |
| Ikarian Capital, LLC | 519.1K | $343.6K | — | Held |
| BlackRock, Inc. | 422.8K | $279.8K | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 352.8K | $233.6K | — | Held |
| LUMINUS MANAGEMENT LLC | 350K | $231.7K | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 334.8K | $221.6K | — | Held |
| AdvisorShares Investments LLC | 250.2K | $165.6K | — | Held |
| STEMPOINT CAPITAL LP | 616.7K | $142.1K | — | Held |
| MILLENNIUM MANAGEMENT LLC | 197K | $130.4K | — | Held |
| TWO SIGMA INVESTMENTS, LP | 195.6K | $129.4K | — | Held |
| Renaissance Technologies | 160.8K | $106.4K | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 151.9K | $100.6K | — | Held |
| TWO SIGMA ADVISERS, LP | 137.7K | $91.2K | — | Held |
| BOOTHBAY FUND MANAGEMENT, LLC | 134.6K | $89.1K | — | Held |
| State Street | 121.1K | $80.2K | — | Held |
| GROUP ONE TRADING LLC | 106.1K | $70.3K | — | Held |
| OMERS ADMINISTRATION Corp | 103.4K | $68.4K | — | Held |
| DIADEMA PARTNERS LP | 100K | $66.2K | — | Held |
| TUDOR INVESTMENT CORP ET AL | 76.2K | $50.4K | — | New |
| NORTHERN TRUST CORP | 72.7K | $48.1K | — | Held |
| Seven Fleet Capital Management LP | 62.7K | $41.5K | — | Held |
| Qube Research & Technologies Ltd | 60.1K | $39.8K | — | Held |
| OCCUDO QUANTITATIVE STRATEGIES LP | 59K | $39.1K | — | Held |
| UBS Group AG | 52K | $34.4K | — | Held |
| AMERICAN CENTURY COMPANIES INC | 48.8K | $32.3K | — | Held |
| Engineers Gate Manager LP | 30.5K | $20.2K | — | Held |
| Persistent Asset Partners Ltd | 26.6K | $17.6K | −$76.9K | Cut−$249.8K |
| Kestra Advisory Services, LLC | 26K | $17.2K | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 23.3K | $15.4K | — | Held |
| Schonfeld Strategic Advisors LLC | 21.7K | $14.4K | — | Held |
| HighTower Advisors, LLC | 20.6K | $13.7K | — | Held |
| Lighthouse Investment Partners, LLC | 20.6K | $13.6K | — | Held |
| MARSHALL WACE, LLP | 20K | $13.2K | — | Held |
| Truvestments Capital LLC | 17K | $11.2K | — | Held |
| Caption Management, LLC | 16.8K | $11.1K | — | Held |
| StoneX Group Inc. | 13.3K | $8.84K | — | Held |
| MORGAN STANLEY | 12.7K | $8.38K | −$36.6K | Cut−$89.4K |
| DRW Securities, LLC | 10K | $6.62K | — | Held |
| Tower Research Capital LLC (TRC) | 8.56K | $5.67K | — | Held |
| OSAIC HOLDINGS, INC. | 5.27K | $3.48K | — | Held |
| BANK OF AMERICA CORP /DE/ | 3.15K | $2.08K | −$9.09K | Cut−$121K |
| Performa Ltd (US), LLC | 1K | $662 | — | Held |
| MAI Capital Management | 526 | $349 | — | Held |
| SBI Securities Co., Ltd. | 288 | $191 | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 114 | $75 | — | Held |
| Virtu Financial LLC | 37.7K | $25 | — | Held |
| HRT FINANCIAL LP | 37.6K | $24 | — | Held |
| Fairman Group, LLC | 29 | $19 | — | Held |
| JPMORGAN CHASE & CO | 16 | $11 | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 13 | $9 | — | Held |
| CWM, LLC | 582 | $0 | — | Held |