| RTW INVESTMENTS, LP | 6.58M | $50.8M | — | Held |
| Deep Track Capital, LP | 5.74M | $44.3M | — | Held |
| BlackRock, Inc. | 4.75M | $36.7M | — | Held |
| Vanguard | 4.15M | $32.1M | — | Held |
| Polar Capital Holdings Plc | 3.93M | $30.3M | — | Held |
| ARMISTICE CAPITAL, LLC | 3.54M | $27.3M | — | Held |
| State Street | 3.22M | $24.9M | — | Held |
| Balyasny Asset Management L.P. | 3.2M | $24.7M | — | Held |
| Foresite Capital Management VI LLC | 3.14M | $24.2M | — | Held |
| Stonepine Capital Management, LLC | 2.73M | $21.1M | — | Held |
| Citadel | 2.35M | $18.2M | — | Held |
| FARALLON CAPITAL MANAGEMENT LLC | 2M | $15.4M | — | New |
| SymBiosis Capital Partners, LLC | 2M | $15.4M | — | Held |
| MORGAN STANLEY | 1.87M | $14.4M | −$1.75M | Added$501.6K |
| Rosalind Advisors, Inc. | 1.79M | $13.8M | — | Held |
| Logos Global Management LP | 1.7M | $13.1M | — | Held |
| GOLDMAN SACHS GROUP INC | 1.5M | $11.5M | — | Held |
| ACORN CAPITAL ADVISORS, LLC | 1.47M | $11.3M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 1.39M | $10.8M | — | Held |
| NEXTBio Capital Management LP | 1.31M | $10.1M | — | Held |
| Vivo Capital, LLC | 1.11M | $8.54M | — | Held |
| TANG CAPITAL MANAGEMENT LLC | 1.07M | $8.26M | — | Held |
| Point72 Asset Management, L.P. | 995K | $7.68M | — | Held |
| J. Goldman & Co LP | 947.3K | $7.31M | — | Held |
| FRANKLIN RESOURCES INC | 926K | $7.15M | — | Held |
| Jefferies Financial Group Inc. | 557K | $4.3M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 555.1K | $4.29M | — | Held |
| UBS Group AG | 501.5K | $3.87M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 476.9K | $3.68M | — | Held |
| Nantahala Capital Management, LLC | 462.1K | $3.57M | — | Held |
| TORONTO DOMINION BANK | 460.4K | $3.55M | — | Held |
| Exome Asset Management LLC | 401.7K | $3.1M | — | Held |
| TWO SIGMA ADVISERS, LP | 399K | $3.08M | — | Held |
| Fidelity | 398.5K | $3.08M | — | Held |
| NORTHERN TRUST CORP | 393.1K | $3.03M | — | Held |
| Pinnacle Financial Partners, Inc. | 390.5K | $3.01M | — | Held |
| CITIGROUP INC | 364.4K | $2.81M | — | Held |
| Y-Intercept (Hong Kong) Ltd | 364.3K | $2.81M | — | Held |
| SPHERA FUNDS MANAGEMENT LTD. | 343.7K | $2.65M | — | Held |
| D. E. Shaw & Co., Inc. | 338.9K | $2.62M | — | Held |
| JANE STREET GROUP, LLC | 320.8K | $2.48M | — | Held |
| BANK OF AMERICA CORP /DE/ | 316.9K | $2.45M | −$166.3K | Added$1.12M |
| Squarepoint Ops LLC | 275.9K | $2.13M | — | Held |
| Ishara Investments LP | 270K | $2.08M | — | Held |
| Polymer Capital Management (HK) LTD | 266.8K | $2.06M | — | Held |
| Qube Research & Technologies Ltd | 254.9K | $1.97M | — | Held |
| PANAGORA ASSET MANAGEMENT INC | 244.1K | $1.88M | — | Held |
| Torray Investment Partners LLC | 216.4K | $1.67M | — | Held |
| Ikarian Capital, LLC | 213.9K | $1.65M | — | Held |
| BARCLAYS PLC | 201.8K | $1.56M | −$186.9K | Added$71.5K |
| RAYMOND JAMES FINANCIAL INC | 199.3K | $1.54M | — | Held |
| Nuveen, LLC | 188.7K | $1.46M | — | Held |
| Hennion & Walsh Asset Management, Inc. | 174.4K | $1.35M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 161.2K | $1.24M | — | Held |
| Trexquant Investment LP | 154.8K | $1.19M | — | Held |
| Birchview Capital, LP | 150K | $1.16M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 145.5K | $1.12M | — | Held |
| ACUTA CAPITAL PARTNERS, LLC | 143.4K | $1.11M | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 143.3K | $1.11M | — | Held |
| XTX Topco Ltd | 131.1K | $1.01M | — | Held |
| Rafferty Asset Management, LLC | 129.3K | $998.5K | — | Held |
| BURKEHILL GLOBAL MANAGEMENT, LP | 125K | $965K | — | Held |
| Bank of New York Mellon Corp | 122.7K | $947.2K | — | Held |
| ExodusPoint Capital Management, LP | 104.9K | $810.2K | — | Held |
| Invesco Ltd. | 104.1K | $803.6K | — | Held |
| ROYAL BANK OF CANADA | 96K | $741K | — | Held |
| JANUS HENDERSON GROUP PLC | 88.9K | $685.9K | — | Held |
| PRELUDE CAPITAL MANAGEMENT, LLC | 74.2K | $573K | — | Held |
| Caption Management, LLC | 70.4K | $543.5K | — | Held |
| BOOTHBAY FUND MANAGEMENT, LLC | 68.5K | $529.1K | — | Held |
| ALLIANCEBERNSTEIN L.P. | 67.3K | $519.3K | — | Held |
| WELLS FARGO & COMPANY/MN | 62.6K | $483.2K | — | Held |
| RHUMBLINE ADVISERS | 60.5K | $467.1K | — | Held |
| FOX RUN MANAGEMENT, L.L.C. | 57.1K | $441.1K | — | Held |
| Icahn Capital | 49K | $378.3K | — | Held |
| PROFUND ADVISORS LLC | 47.7K | $368K | — | Held |
| DEUTSCHE BANK AG\ | 45.6K | $351.8K | — | Held |
| Cetera Investment Advisers | 43.4K | $334.9K | — | Held |
| ENVESTNET ASSET MANAGEMENT INC | 42.5K | $327.9K | — | Held |
| CANTOR FITZGERALD, L. P. | 42.3K | $326.2K | — | New |
| STIFEL FINANCIAL CORP | 39.8K | $307K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 39.1K | $301.9K | — | Held |
| VARCOV Co. | 33.8K | $260.7K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 32.4K | $248.4K | — | Held |
| Aquatic Capital Management LLC | 30.9K | $238.8K | — | Held |
| MetLife Investment Management, LLC | 28.9K | $223.3K | — | Held |
| Virtus Investment Advisers, LLC | 27.7K | $213.7K | — | Held |
| Quarry LP | 27K | $208.4K | — | Held |
| Aries Wealth Management | 26.2K | $202.6K | — | Held |
| NewEdge Wealth, LLC | 25.9K | $199.8K | — | Held |
| Brevan Howard Capital Management LP | 25.2K | $194.3K | — | Held |
| Graham Capital Management, L.P. | 23.4K | $180.9K | — | Held |
| JPMORGAN CHASE & CO | 22.4K | $172.6K | — | Held |
| Entropy Technologies, LP | 20.8K | $160.5K | — | Held |
| OSAIC HOLDINGS, INC. | 20.5K | $158.1K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 19.2K | $148.4K | — | Held |
| GROUP ONE TRADING LLC | 17.9K | $138.1K | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 16.4K | $126.7K | — | Held |
| Seven Fleet Capital Management LP | 15.1K | $116.9K | — | Held |
| Creative Planning | 15K | $116K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 12.6K | $97.4K | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 12.5K | $96.5K | — | Held |
| DRW Securities, LLC | 12K | $92.6K | — | Held |
| SIMPLEX TRADING, LLC | 7.49K | $57.8K | — | Held |
| Legal & General Group Plc | 5.29K | $40.8K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 5.2K | $39.9K | — | Held |
| Russell Investments Group, Ltd. | 4.63K | $35.7K | — | Held |
| Ameritas Investment Partners, Inc. | 3.89K | $30K | — | Held |
| LORING WOLCOTT & COOLIDGE FIDUCIARY ADVISORS LLP/MA | 4.5K | $29.3K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 3.51K | $27.1K | — | Held |
| Tower Research Capital LLC (TRC) | 3.41K | $26.3K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3.29K | $25.4K | — | Held |
| Rockefeller Capital Management L.P. | 2.17K | $16.8K | — | Held |
| FLAGSHIP HARBOR ADVISORS, LLC | 1.8K | $13.9K | — | New |
| AlphaQuest LLC | 1.76K | $13.6K | — | Held |
| Sterling Capital Management LLC | 1.54K | $11.9K | — | Held |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 850 | $6.56K | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 623 | $4.81K | — | Held |
| EverSource Wealth Advisors, LLC | 426 | $3.29K | — | Held |
| Clearstead Advisors, LLC | 416 | $3.21K | — | Held |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 400 | $3.09K | — | Held |
| SG Americas Securities, LLC | 390.3K | $3.01K | — | Held |
| Optiver Holding B.V. | 368 | $2.84K | — | Held |
| Arax Advisory Partners | 298 | $2.3K | — | Held |
| SBI Securities Co., Ltd. | 154 | $1.19K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 143 | $1.1K | — | Held |
| Torren Management, LLC | 107 | $826 | — | Held |
| GAMMA Investing LLC | 107 | $826 | — | Held |
| Farther Finance Advisors, LLC | 55 | $425 | — | Held |
| US BANCORP \DE\ | 46 | $355 | — | Held |
| IFP Advisors, Inc | 41 | $317 | −$45 | Cut−$45 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 27.2K | $211 | — | Held |
| SIGNATUREFD, LLC | 27 | $208 | — | Held |
| Sunbelt Securities, Inc. | 27 | $208 | — | Held |
| HARBOUR INVESTMENTS, INC. | 14 | $108 | — | Held |
| ALGERT GLOBAL LLC | 11K | $85 | — | Held |
| PNC Financial Services Group, Inc. | 11 | $85 | — | Held |
| Global Retirement Partners, LLC | 8 | $62 | — | Held |
| Inspire Investing, LLC | 3 | $22 | — | Held |
| Cygnus Capital Advisors, LLC | 1.89K | $15 | — | Held |
| AMALGAMATED BANK | 1.68K | $13 | — | Held |
| CWM, LLC | 570 | $4 | — | Held |