| Opaleye Management Inc. | 2.86M | $48.4M | — | Held |
| EcoR1 Capital, LLC | 2.03M | $34.3M | — | Held |
| BlackRock, Inc. | 1.74M | $29.4M | — | Held |
| Vanguard | 1.35M | $22.8M | — | Held |
| Nantahala Capital Management, LLC | 1.18M | $19.9M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 565.1K | $9.56M | — | Held |
| State Street | 501.9K | $8.49M | — | Held |
| MORGAN STANLEY | 493.9K | $8.35M | −$2.38M | Cut−$4.38M |
| National Philanthropic Trust | 492.1K | $8.32M | −$2.37M | Cut−$2.37M |
| Westside Investment Management, Inc. | 470.9K | $7.96M | — | Held |
| OBERWEIS ASSET MANAGEMENT INC/ | 431.3K | $7.29M | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 277.5K | $4.69M | — | Held |
| NORTHERN TRUST CORP | 231.8K | $3.92M | — | Held |
| CANNELL CAPITAL LLC | 216.9K | $3.67M | — | Held |
| Renaissance Technologies | 205.7K | $3.48M | — | Held |
| GOLDMAN SACHS GROUP INC | 196.3K | $3.32M | — | Held |
| Diametric Capital, LP | 193.2K | $3.27M | — | Held |
| JPMORGAN CHASE & CO | 185.4K | $3.14M | — | Held |
| Lumbard & Kellner, LLC | 174.9K | $2.96M | — | Held |
| Aristides Capital LLC | 161.4K | $2.73M | — | Held |
| Bank of New York Mellon Corp | 127.7K | $2.16M | — | Held |
| UBS Group AG | 126.7K | $2.14M | — | Held |
| Jefferies Financial Group Inc. | 118.3K | $2M | — | Held |
| BANK OF AMERICA CORP /DE/ | 104.8K | $1.77M | −$359.8K | Added$149.8K |
| Woodline Partners LP | 95.5K | $1.61M | — | Held |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 84K | $1.42M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 81.2K | $1.37M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 79.3K | $1.34M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 77.2K | $1.31M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 76.6K | $1.3M | — | Held |
| Connor, Clark & Lunn Investment Management Ltd. | 76.6K | $1.3M | — | Held |
| Citadel | 74.1K | $1.25M | — | Held |
| Nuveen, LLC | 58.9K | $996.3K | — | Held |
| JANE STREET GROUP, LLC | 58.1K | $981.7K | — | Held |
| BARCLAYS PLC | 51.4K | $870K | −$177.4K | Added$70.2K |
| Russell Investments Group, Ltd. | 49.7K | $840.3K | — | Held |
| PRELUDE CAPITAL MANAGEMENT, LLC | 45.3K | $766.4K | — | Held |
| ANCHOR CAPITAL ADVISORS LLC | 40.7K | $687.7K | — | Held |
| XTX Topco Ltd | 32.5K | $550K | — | Held |
| BLAIR WILLIAM & CO/IL | 32.4K | $547.9K | — | Held |
| RHUMBLINE ADVISERS | 30.4K | $514.7K | — | Held |
| WELLS FARGO & COMPANY/MN | 28.3K | $478.4K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 24.6K | $416.2K | — | Held |
| Guilbault Capital LLC | 23.2K | $392.7K | — | Held |
| Aquatic Capital Management LLC | 22.8K | $385.6K | — | Held |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 20.2K | $341.3K | — | Held |
| Invesco Ltd. | 19.7K | $333K | — | Held |
| JUNCTURE WEALTH STRATEGIES, LLC | 19K | $321.2K | — | Held |
| Bridge City Capital, LLC | 18.6K | $314.5K | — | Held |
| DEUTSCHE BANK AG\ | 18.2K | $308.6K | — | Held |
| CHICAGO TRUST Co NA | 16.7K | $282.4K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 14.6K | $267K | — | Held |
| Voleon Capital Management LP | 15.6K | $263.5K | — | Held |
| MetLife Investment Management, LLC | 15.5K | $262.7K | — | Held |
| D. E. Shaw & Co., Inc. | 15.3K | $259.2K | — | Held |
| PDT Partners, LLC | 14.9K | $251.8K | — | Held |
| TWO SIGMA ADVISERS, LP | 14.7K | $248.6K | — | Held |
| Squarepoint Ops LLC | 13.5K | $228K | — | Held |
| Point72 Asset Management, L.P. | 12.9K | $218.6K | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 12.5K | $211.4K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 12.4K | $210K | — | Held |
| RAYMOND JAMES FINANCIAL INC | 12.3K | $207.1K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 11.9K | $200.6K | — | Held |
| Quantum Private Wealth, LLC | 11.5K | $194.5K | — | Held |
| ENVESTNET ASSET MANAGEMENT INC | 10.9K | $185.1K | — | Held |
| Jump Financial, LLC | 10.6K | $178.4K | — | Held |
| Man Group plc | 10.5K | $177.1K | — | Held |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 10K | $169.1K | — | Held |
| Quantbot Technologies LP | 9.36K | $158.2K | — | Held |
| State of Wyoming | 8.16K | $138K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 8.1K | $137K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 7.21K | $121.9K | — | Held |
| China Universal Asset Management Co., Ltd. | 4.37K | $73.9K | — | Held |
| AlphaQuest LLC | 4.15K | $70.2K | — | Held |
| Fidelity | 3.08K | $52K | — | Held |
| Tower Research Capital LLC (TRC) | 2.99K | $50.6K | — | Held |
| Caitong International Asset Management Co., Ltd | 2.94K | $49.7K | — | Held |
| Legal & General Group Plc | 2.73K | $46.2K | — | Held |
| Ameritas Investment Partners, Inc. | 2.17K | $36.6K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1.58K | $26.7K | — | Held |
| CITIGROUP INC | 1.45K | $24.5K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 1.3K | $22K | — | Held |
| Truvestments Capital LLC | 1.18K | $20K | — | Held |
| ROYAL BANK OF CANADA | 1.02K | $17K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 527 | $8.91K | — | Held |
| GROUP ONE TRADING LLC | 500 | $8.46K | — | Held |
| THOMPSON SIEGEL & WALMSLEY LLC | 408.5K | $6.91K | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 221 | $3.74K | — | Held |
| OSAIC HOLDINGS, INC. | 200 | $3.38K | — | Held |
| Sterling Capital Management LLC | 167 | $2.82K | — | Held |
| Vermillion & White Wealth Management Group, LLC | 150 | $2.54K | — | Held |
| Farther Finance Advisors, LLC | 146 | $2.47K | — | Held |
| US BANCORP \DE\ | 54 | $913 | — | Held |
| PNC Financial Services Group, Inc. | 51 | $862 | — | Held |
| GAMMA Investing LLC | 23 | $389 | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 15.4K | $260 | — | Held |
| SBI Securities Co., Ltd. | 10 | $169 | — | Held |
| Allworth Financial LP | 7 | $119 | — | New |
| State of Alaska, Department of Revenue | 6.94K | $117 | — | Held |
| SG Americas Securities, LLC | 6.47K | $109 | — | Held |
| Hughes Financial Services, LLC | 1 | $17 | — | Held |
| AMALGAMATED BANK | 805 | $14 | — | Held |
| Daiwa Securities Group Inc. | 89 | $2 | — | Held |
| CWM, LLC | 26 | $0 | — | Held |