| TCG Crossover Management, LLC | 7.92M | $33M | — | New |
| Commodore Capital LP | 6.34M | $26.4M | — | New |
| Avidity Partners Management LP | 6.05M | $25.2M | $4.56M | Added$16.4M |
| BlackRock, Inc. | 5.35M | $22.3M | $6.48M | Added$9.76M |
| Opaleye Management Inc. | 4.88M | $20.3M | −$50.5K | Added$15.3M |
| VANGUARD CAPITAL MANAGEMENT LLC | 4.38M | $18.3M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 4.05M | $16.9M | $2M | Added$13M |
| Citadel | 3.57M | $14.9M | $384.1K | Added$14.1M |
| Affinity Asset Advisors, LLC | 3.16M | $13.2M | $426K | Added$12.4M |
| State Street | 3.13M | $13.1M | $1.62M | Added$9.92M |
| Balyasny Asset Management L.P. | 2.99M | $12.5M | — | New |
| MORGAN STANLEY | 2.98M | $12.4M | $4.24M | Added$135.6K |
| Spruce Street Capital LP | 2.63M | $11M | — | New |
| GEODE CAPITAL MANAGEMENT, LLC | 1.77M | $7.37M | $2.01M | Added$3.48M |
| Patient Square Capital LP | 1.63M | $6.78M | $1.61M | Added$3.66M |
| Nicholson Wealth Management Group, LLC | 1.62M | $6.75M | $2.3M | Added$2.3M |
| GOLDMAN SACHS GROUP INC | 1.24M | $5.18M | $227K | Added$4.74M |
| Yu Fan | 1.06M | $4.4M | — | New |
| TWO SIGMA INVESTMENTS, LP | 1M | $4.18M | $1.42M | Added$888.2K |
| Ally Bridge Group (NY) LLC | 926.6K | $3.86M | — | New |
| Nuveen, LLC | 910.2K | $3.8M | $1.29M | Added$292.1K |
| Hills Bank & Trust Co | 872.2K | $3.64M | $1.24M | Added$1.06M |
| Octagon Capital Advisors LP | 791.6K | $3.3M | — | New |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 752K | $3.14M | — | Held |
| ADAR1 Capital Management, LLC | 749.3K | $3.12M | $135.2K | Added$2.86M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 661.3K | $2.76M | $760.4K | Added$1.29M |
| VANGUARD FIDUCIARY TRUST CO | 566.7K | $2.36M | — | Held |
| NORTHERN TRUST CORP | 528.9K | $2.21M | $623.7K | Added$997.8K |
| UBS Group AG | 520.9K | $2.17M | $739.7K | Cut−$375.2K |
| DIMENSIONAL FUND ADVISORS LP | 450.1K | $1.88M | $130K | Added$1.63M |
| WealthPlan Investment Management, LLC | 404.1K | $1.68M | $573.8K | Added$573.8K |
| Seven Fleet Capital Management LP | 379.1K | $1.58M | — | New |
| Fidelity | 313.7K | $1.31M | $436K | Added$463.6K |
| PORTLAND INVESTMENT COUNSEL INC. | 250K | $1.04M | $355K | Added$355K |
| BANK OF AMERICA CORP /DE/ | 241.9K | $1.01M | $343.5K | Cut−$158.6K |
| Invesco Ltd. | 231.4K | $964.8K | $34.5K | Added$898K |
| FEDERATED HERMES, INC. | 222.1K | $926.3K | $303.5K | Added$338.5K |
| CITIGROUP INC | 212.1K | $884.6K | $106.6K | Added$678.2K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 186.6K | $778.2K | $115.6K | Added$554.3K |
| Bank of New York Mellon Corp | 185.3K | $772.8K | $263.2K | Added$254.2K |
| Jefferies Financial Group Inc. | 183.3K | $764.5K | — | New |
| Squarepoint Ops LLC | 169.1K | $705.3K | — | New |
| WELLINGTON MANAGEMENT GROUP LLP | 168.2K | $701.5K | — | New |
| Rothschild Wealth LLC | 164.8K | $687.3K | $233.9K | Added$234.3K |
| STATE OF WISCONSIN INVESTMENT BOARD | 119.1K | $496.7K | — | New |
| ExodusPoint Capital Management, LP | 117.1K | $488.1K | — | New |
| VOYA INVESTMENT MANAGEMENT LLC | 115.5K | $481.6K | $15.2K | Added$452.2K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 110.8K | $462K | $136K | Added$198.6K |
| Trueblood Wealth Management, LLC | 99.1K | $413.1K | $140.7K | Added$85.7K |
| Rafferty Asset Management, LLC | 92.8K | $387K | — | New |
| RHUMBLINE ADVISERS | 77.1K | $321.5K | $108.7K | Added$110.9K |
| Vanguard Global Advisers, LLC | 74K | $308.4K | — | Held |
| Creative Planning | 71.5K | $298K | $57.4K | Added$186.9K |
| Quantinno Capital Management LP | 65.5K | $273.1K | — | New |
| Corient Private Wealth LLC | 61.9K | $258K | — | New |
| Caption Management, LLC | 60K | $250.2K | — | New |
| ALLIANCEBERNSTEIN L.P. | 83.5K | $229.5K | $0 | Held |
| DEUTSCHE BANK AG\ | 53.2K | $221.7K | $75.5K | Added$72.5K |
| SIMPLEX TRADING, LLC | 42.5K | $177.2K | — | New |
| PROFUND ADVISORS LLC | 41.6K | $173.3K | — | New |
| SYKON CAPITAL LLC | 37.9K | $158.2K | $53.9K | Added$53.9K |
| AMERICAN CENTURY COMPANIES INC | 35.7K | $149K | $17.8K | Added$114.4K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 34.8K | $143.1K | $37.5K | Added$67K |
| TUDOR INVESTMENT CORP ET AL | 33.9K | $141.6K | — | New |
| MetLife Investment Management, LLC | 33.1K | $137.9K | $23.7K | Added$92K |
| WEALTH EFFECTS LLC | 33K | $137.6K | $35.5K | Added$68.9K |
| Taylor & Morgan Wealth Management, LLC | 29K | $120.9K | $41.2K | Cut−$145.8K |
| JPMORGAN CHASE & CO | 29.2K | $112K | $30.3K | Added$34.9K |
| Icahn Capital | 26.7K | $111.4K | — | New |
| Koa Wealth Management, LLC | 26K | $108.3K | $36.9K | Added$36.9K |
| WINTON GROUP Ltd | 24.3K | $101.3K | — | New |
| MONETA GROUP INVESTMENT ADVISORS LLC | 23.7K | $98.9K | $33.7K | Added$33.7K |
| WELLS FARGO & COMPANY/MN | 23.5K | $98K | $33.4K | Cut−$85.8K |
| Hudson Bay Capital Management LP | 23.1K | $96.3K | — | New |
| MERCER GLOBAL ADVISORS INC /ADV | 22.3K | $92.9K | $31.6K | Added$16.7K |
| BNP PARIBAS FINANCIAL MARKETS | 21.7K | $90.3K | $17.8K | Added$55.9K |
| CIBC Asset Management Inc | 20.9K | $87.2K | $29.7K | Added$29.7K |
| Police & Firemen's Retirement System of New Jersey | 20.8K | $86.7K | $29.5K | Added$29.5K |
| HighTower Advisors, LLC | 20K | $83.5K | $28.4K | Cut−$17.9K |
| INTECH INVESTMENT MANAGEMENT LLC | 19.5K | $81.3K | $27.7K | Added$10.7K |
| Iowa State Bank | 19.1K | $79.5K | $27.1K | Added$27.1K |
| Vontobel Holding Ltd. | 18K | $75.1K | $25.6K | Added$6.43K |
| AXQ CAPITAL, LP | 17K | $71.1K | $18.1K | Added$36K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 16.7K | $69.6K | $23.7K | Added$17.2K |
| Qube Research & Technologies Ltd | 15.6K | $65.1K | $22.2K | Cut−$158.5K |
| AUCTUS ADVISORS LLC | 15.5K | $64.8K | $22.1K | Cut−$22.3K |
| BARCLAYS PLC | 15K | $62.8K | $21.4K | Cut−$192.4K |
| Dynamic Technology Lab Private Ltd | 14.1K | $58.6K | — | New |
| Polymer Capital Management (US) LLC | 13.1K | $54.6K | — | New |
| NISA INVESTMENT ADVISORS, LLC | 12.7K | $52.9K | $199 | Added$52.5K |
| Susquehanna Portfolio Strategies, LLC | 12.5K | $52.2K | — | New |
| Scientech Research LLC | 11.9K | $49.6K | — | New |
| Mariner, LLC | 11.8K | $49.3K | — | New |
| Abel Hall, LLC | 11.8K | $49.2K | — | New |
| Tower Research Capital LLC (TRC) | 11.7K | $48.7K | $14.5K | Added$20.7K |
| E Fund Management Co., Ltd. | 11.7K | $48.7K | — | Held |
| PRUDENTIAL FINANCIAL INC | 10.8K | $45.1K | — | New |
| VICTORY CAPITAL MANAGEMENT INC | 10.6K | $44.1K | — | New |
| NEW YORK STATE COMMON RETIREMENT FUND | 10.3K | $43K | $14.6K | Added$14.6K |
| Pekin Hardy Strauss, Inc. | 10K | $41.7K | — | New |
| Russell Investments Group, Ltd. | 8.48K | $35.3K | $12K | Added$12K |
| Ameritas Investment Partners, Inc. | 5.48K | $22.8K | $7.78K | Added$7.78K |
| Legal & General Group Plc | 5.43K | $22.6K | $7.7K | Added$7.7K |
| STRS OHIO | 5.3K | $22.1K | $7.53K | Added$7.53K |
| ROYAL BANK OF CANADA | 4.5K | $19K | $6.88K | Added$3K |
| JDM Financial Group LLC | 3.5K | $14.6K | $4.97K | Added$4.97K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3.43K | $14.3K | $4.87K | Added$4.22K |
| Rockefeller Capital Management L.P. | 3K | $12.5K | $4.26K | Added$4.26K |
| GROUP ONE TRADING LLC | 2.15K | $8.99K | $3.06K | Cut−$1.38K |
| Sterling Capital Management LLC | 2.07K | $8.64K | $2.94K | Cut−$806 |
| TORONTO DOMINION BANK | 1.74K | $7.24K | — | New |
| CWM, LLC | 1.42K | $5.92K | $438 | Added$5.92K |
| VESTOR CAPITAL, LLC | 1.1M | $4.58K | −$2.67K | Added$1.91K |
| JONES FINANCIAL COMPANIES LLLP | 1.02K | $4.16K | $185 | Added$3.77K |
| GAMMA Investing LLC | 586 | $2.44K | $277 | Added$1.91K |
| NATIONAL BANK OF CANADA /FI/ | 582 | $2.41K | $819 | Added$619 |
| OSAIC HOLDINGS, INC. | 500 | $2.08K | $710 | Cut−$2.04K |
| JNBA Financial Advisors | 500 | $2.08K | $710 | Added$710 |
| Farther Finance Advisors, LLC | 348 | $1.54K | $581 | Added$573 |
| US BANCORP \DE\ | 344 | $1.43K | — | New |
| Caitong International Asset Management Co., Ltd | 339 | $1.41K | $482 | Cut−$82.8K |
| PNC Financial Services Group, Inc. | 221 | $922 | $108 | Added$713 |
| TD Waterhouse Canada Inc. | 200 | $876 | $328 | Added$328 |
| Vermillion Wealth Management, Inc. | 194 | $809 | $275 | Added$275 |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 90 | $398 | $150 | Added$150 |
| Fortitude Family Office, LLC | 93 | $388 | — | New |
| Advisory Services Network, LLC | 44 | $183 | — | New |
| PRICE T ROWE ASSOCIATES INC /MD/ | 42.3K | $177 | $43 | Added$95 |
| GSA CAPITAL PARTNERS LLP | 37.3K | $156 | $53 | Cut−$81 |
| Allworth Financial LP | 35 | $146 | — | New |
| MAI Capital Management | 35 | $146 | — | New |
| EverSource Wealth Advisors, LLC | 35 | $146 | $1 | Added$143 |
| ROTHSCHILD INVESTMENT LLC | 34 | $142 | $10 | Added$123 |
| Transamerica Financial Advisors, LLC | 25 | $104 | — | New |
| Virtu Financial LLC | 14.9K | $62 | — | New |
| Essential Partners LLC | 5 | $21 | — | New |
| Keating Financial Advisory Services, Inc. | 2 | $8 | — | New |
| SBI Securities Co., Ltd. | 1 | $4 | $1 | Added$1 |