| TCG Crossover Management, LLC | 10M | $15.6M | — | Held |
| BlackRock, Inc. | 7.15M | $11.2M | — | Held |
| Vanguard | 6.91M | $10.8M | — | Held |
| Foresite Capital Management IV, LLC | 3.89M | $6.06M | — | Held |
| Merck & Co., Inc. | 3.55M | $5.53M | — | Held |
| 683 Capital Management, LLC | 3.35M | $5.23M | — | Held |
| Balyasny Asset Management L.P. | 3.27M | $5.09M | — | Held |
| D. E. Shaw & Co., Inc. | 2.37M | $3.69M | — | Held |
| Fidelity | 2.23M | $3.48M | — | Held |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 2.17M | $3.39M | — | Held |
| Ikarian Capital, LLC | 2.08M | $3.25M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 2.08M | $3.24M | — | Held |
| Kynam Capital Management, LP | 2M | $3.12M | — | Held |
| State Street | 1.81M | $2.83M | — | Held |
| Renaissance Technologies | 1.54M | $2.41M | — | Held |
| MEDICI CAPITAL LLC | 1.5M | $2.34M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 1.33M | $2.08M | — | Held |
| Euclidean Capital LLC | 1.31M | $2.04M | — | Held |
| MARSHALL WACE, LLP | 1.17M | $1.82M | — | Held |
| Spruce Street Capital LP | 1.12M | $1.74M | — | Held |
| ADAR1 Capital Management, LLC | 1.11M | $1.73M | — | Held |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1.06M | $1.65M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 1.04M | $1.62M | — | Held |
| DEUTSCHE BANK AG\ | 1.04M | $1.61M | — | Held |
| Eversept Partners, LP | 1.01M | $1.57M | — | Held |
| JANE STREET GROUP, LLC | 993.9K | $1.55M | — | Held |
| DAFNA Capital Management LLC | 908.4K | $1.42M | — | Held |
| Elmind Capital, LP | 900K | $1.4M | — | Held |
| PANAGORA ASSET MANAGEMENT INC | 850.3K | $1.33M | — | Held |
| Vestal Point Capital, LP | 755K | $1.18M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 665.5K | $1.04M | — | Held |
| TWO SIGMA ADVISERS, LP | 651.8K | $1.02M | — | Held |
| MACKENZIE FINANCIAL CORP | 660.2K | $1M | — | Held |
| Icahn Capital | 599.6K | $935.3K | — | Held |
| XTX Topco Ltd | 592.8K | $924.8K | — | Held |
| NORTHERN TRUST CORP | 587.7K | $916.7K | — | Held |
| BOOTHBAY FUND MANAGEMENT, LLC | 559.7K | $873.2K | — | Held |
| GOLDMAN SACHS GROUP INC | 438K | $683.2K | — | Held |
| BARCLAYS PLC | 398.7K | $622K | −$558.2K | Cut−$1.96M |
| AMERIPRISE FINANCIAL INC | 354.3K | $552.7K | — | Held |
| MORGAN STANLEY | 319.1K | $497.8K | −$446.7K | Cut−$787.4K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 291.2K | $454.2K | — | Held |
| Invesco Ltd. | 279.5K | $436K | — | Held |
| Bank of New York Mellon Corp | 217.9K | $339.9K | — | Held |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | 200K | $312K | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 199.1K | $310.5K | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 172.3K | $268.8K | — | Held |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 136K | $212.2K | — | Held |
| BANK OF AMERICA CORP /DE/ | 134.5K | $209.8K | −$188.3K | Cut−$519.2K |
| Utah Retirement Systems | 133.7K | $208.6K | — | Held |
| Nuveen, LLC | 133.2K | $207.9K | — | Held |
| UBS Group AG | 119.4K | $186.3K | — | Held |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 115K | $179.4K | — | Held |
| STRS OHIO | 110.4K | $172.2K | — | Held |
| Graham Capital Management, L.P. | 104.9K | $163.6K | — | Held |
| RHUMBLINE ADVISERS | 101.9K | $159K | — | Held |
| Jasper Ridge Partners, L.P. | 95.1K | $148.3K | — | Held |
| Citadel | 93.5K | $145.9K | — | Held |
| ALLIANCEBERNSTEIN L.P. | 92.9K | $145K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 93.1K | $141.4K | — | Held |
| WELLS FARGO & COMPANY/MN | 90.1K | $140.6K | — | Held |
| Man Group plc | 86.2K | $134.4K | — | Held |
| SIMPLEX TRADING, LLC | 82K | $127.9K | — | Held |
| Squarepoint Ops LLC | 77.6K | $121.1K | — | Held |
| Russell Investments Group, Ltd. | 71.9K | $112.1K | — | Held |
| Blackstone Inc. | 66.9K | $104.3K | — | New |
| Quadrature Capital Ltd | 62.3K | $97.1K | — | Held |
| Cannell & Spears LLC | 54.6K | $85.2K | — | Held |
| Lexington Partners L.P. | 53.5K | $83.4K | — | Held |
| Vanguard Personalized Indexing Management, LLC | 53.1K | $82.8K | — | Held |
| HSBC HOLDINGS PLC | 48.5K | $75.7K | — | Held |
| OXFORD ASSET MANAGEMENT LLP | 42.9K | $66.9K | — | New |
| TUDOR INVESTMENT CORP ET AL | 41.3K | $64.4K | −$57.8K | Cut−$57.8K |
| Tower Research Capital LLC (TRC) | 39.5K | $61.7K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 37.3K | $58.1K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 34.5K | $53.8K | — | Held |
| JPMORGAN CHASE & CO | 32.6K | $50.9K | — | Held |
| PRUDENTIAL FINANCIAL INC | 32.2K | $50.3K | — | Held |
| Vontobel Holding Ltd. | 30K | $46.8K | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 28.8K | $45K | — | Held |
| Dynamic Technology Lab Private Ltd | 25.9K | $40K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 23.4K | $36.5K | — | Held |
| Point72 Asset Management, L.P. | 23.1K | $36K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 22.4K | $34.9K | — | Held |
| HERSHEY TRUST CO | 20.6K | $32.1K | — | Held |
| Bronte Capital Management Pty Ltd. | 19.3K | $30.1K | — | Held |
| SEI INVESTMENTS CO | 16.9K | $26.3K | — | Held |
| ProShare Advisors LLC | 14.7K | $22.9K | — | Held |
| NEUBERGER BERMAN GROUP LLC | 14.2K | $22.1K | — | Held |
| DIVERSIFIED TRUST CO | 14.1K | $22K | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 13.9K | $21.7K | — | Held |
| Cerity Partners LLC | 13.7K | $21.3K | — | Held |
| R Squared Ltd | 12.5K | $19.5K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 10.3K | $16.1K | — | Held |
| Corient Private Wealth LLC | 10.3K | $16K | — | Held |
| HighTower Advisors, LLC | 10K | $15.6K | — | Held |
| Texas Yale Capital Corp. | 10K | $15.6K | — | Held |
| Ameritas Investment Partners, Inc. | 8.18K | $12.8K | — | Held |
| CITIGROUP INC | 6.16K | $9.6K | — | Held |
| Legal & General Group Plc | 6.04K | $9.42K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 4.94K | $7.71K | — | Held |
| ROYAL BANK OF CANADA | 4.68K | $7K | — | Held |
| Sterling Capital Management LLC | 4.42K | $6.9K | — | Held |
| ACADIAN ASSET MANAGEMENT LLC | 3.44M | $5.36K | — | Held |
| GAMMA Investing LLC | 1.07K | $1.68K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 1.02K | $1.58K | — | Held |
| Physician Wealth Advisors, Inc. | 752 | $1.17K | — | Held |
| OSAIC HOLDINGS, INC. | 620 | $967 | — | Held |
| True Wealth Design, LLC | 563 | $879 | — | Held |
| Hughes Financial Services, LLC | 553 | $863 | — | Held |
| EverSource Wealth Advisors, LLC | 504 | $786 | — | Held |
| Essential Partners LLC | 431 | $672 | −$604 | Cut−$897 |
| DekaBank Deutsche Girozentrale | 100K | $661 | — | Held |
| Federation des caisses Desjardins du Quebec | 415 | $647 | — | Held |
| Wilmington Savings Fund Society, FSB | 400 | $624 | — | Held |
| Rockefeller Capital Management L.P. | 367 | $573 | — | Held |
| MARK SHEPTOFF FINANCIAL PLANNING, LLC | 300 | $468 | — | Held |
| GSA CAPITAL PARTNERS LLP | 225.6K | $352 | — | Held |
| ROTHSCHILD INVESTMENT LLC | 209 | $326 | — | Held |
| NATIONAL BANK OF CANADA /FI/ | 200 | $312 | — | Held |
| HRT FINANCIAL LP | 57.3K | $89 | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 56.2K | $89 | — | Held |
| Kingdom Financial Group LLC. | 48 | $75 | — | Held |
| IFP Advisors, Inc | 47 | $73 | −$66 | Cut−$66 |
| SG Americas Securities, LLC | 27K | $42 | — | Held |
| Virtu Financial LLC | 21.9K | $34 | — | Held |
| SBI Securities Co., Ltd. | 20 | $31 | — | Held |
| CWM, LLC | 12.2K | $19 | — | Held |
| COMERICA BANK | 9 | $14 | — | Held |
| AMALGAMATED BANK | 2.52K | $4 | — | Held |