Stock
Reported value
$281.5M
Holders
84
+20 new · −3 exited
Holders’ est. mark
$90.1M
Price effect on 60 books still in the name
Largest holder
$40.5M
ORBIMED ADVISORS LLC
Notable conviction
Share of each notable manager’s 13F book.
- Renaissance Technologies0.0% · $3.89M
- Citadel0.0% · $951.8K
- Fidelity0.0% · $2.52M
- State Street0.0% · $1.7M
Holder count by quarter
Who holds it
Notable only| Investor | Shares | Value | Est. mark | Change |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 6.31M | $40.5M | $17.5M | Added$17.5M |
| Redmile Group, LLC | 5.54M | $35.6M | $15.4M | Added$15.4M |
| Prosight Management, LP | 5M | $32.2M | $6.62M | Added$23.5M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 4.64M | $29.9M | $12.9M | Added$6.85M |
| NEXTBio Capital Management LP | 3.15M | $20.3M | $8.76M | Added$8.76M |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.28M | $14.6M | — | Held |
| CLARK ESTATES INC/NY | 1.48M | $9.49M | $4.1M | Added$4.1M |
| PINNACLE ASSOCIATES LTD | 1.37M | $8.8M | $3.75M | Added$3.87M |
| Aberdeen Group plc | 1.16M | $7.45M | $1.48M | Added$5.52M |
| Point72 Asset Management, L.P. | 1.03M | $6.63M | $2.87M | Added$2.73M |
| AMERIPRISE FINANCIAL INC | 905.7K | $5.82M | $32K | Added$5.78M |
| 683 Capital Management, LLC | 800K | $5.14M | $2.22M | Added$70.5K |
| MILLENNIUM MANAGEMENT LLC | 763.7K | $4.91M | $1.33M | Added$3.17M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 716K | $4.6M | $412.6K | Added$4.06M |
| GEODE CAPITAL MANAGEMENT, LLC | 645.7K | $4.15M | $1.72M | Added$1.9M |
| Renaissance Technologies | 604.5K | $3.89M | $947.1K | Added$2.64M |
| MARSHALL WACE, LLP | 581.5K | $3.74M | $1.36M | Added$1.95M |
| BlackRock, Inc. | 510.8K | $3.28M | $1.16M | Added$1.76M |
| S&G Foundation | 435.7K | $2.8M | — | Held |
| JANE STREET GROUP, LLC | 415.9K | $2.67M | $150.2K | Added$2.48M |
| Fidelity | 392.5K | $2.52M | $1.09M | Added$1.09M |
| TD Asset Management Inc | 382.6K | $2.46M | $697.9K | Added$1.54M |
| VANGUARD FIDUCIARY TRUST CO | 324.6K | $2.09M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 316K | $2.03M | $878.5K | Added$434.2K |
| DIADEMA PARTNERS LP | 293.7K | $1.89M | — | New |
| SPHERA FUNDS MANAGEMENT LTD. | 280.8K | $1.81M | $542.7K | Added$1.09M |
| State Street | 263.8K | $1.7M | $598.9K | Added$909.8K |
| Hudson Bay Capital Management LP | 228.8K | $1.47M | — | New |
| MORGAN STANLEY | 200.1K | $1.29M | $50.3K | Added$1.22M |
| DEUTSCHE BANK AG\ | 194.8K | $1.25M | — | New |
| GOLDMAN SACHS GROUP INC | 191.4K | $1.23M | $356.3K | Added$763.2K |
| DIMENSIONAL FUND ADVISORS LP | 155.6K | $1M | $64.5K | Added$916.1K |
| Citadel | 148K | $951.8K | $191.4K | Added$700.5K |
| XTX Topco Ltd | 142.5K | $916.1K | $69.1K | Added$825.3K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 142.3K | $915K | $382.2K | Added$428.8K |
| Connor, Clark & Lunn Investment Management Ltd. | 139.3K | $895.7K | $182.7K | Added$655.8K |
| Qube Research & Technologies Ltd | 126.8K | $815.3K | $107.7K | Added$673.8K |
| NORTHERN TRUST CORP | 126.1K | $810.6K | $350.4K | Added$279.7K |
| BARCLAYS PLC | 119.9K | $770.8K | — | New |
| Bank of New York Mellon Corp | 89.8K | $577.2K | $249.6K | Added$174.3K |
| BANK OF AMERICA CORP /DE/ | 79.9K | $513.9K | $222.2K | Cut−$3.53M |
| Brevan Howard Capital Management LP | 79.5K | $511K | — | New |
| CITIGROUP INC | 75K | $482.3K | $69K | Added$391.6K |
| Persistent Asset Partners Ltd | 74.2K | $477.3K | — | New |
| Pathstone Holdings, LLC | 74K | $475.5K | $205.6K | Cut−$97.8K |
| Hillsdale Investment Management Inc. | 65.4K | $420.5K | — | New |
| Davis Asset Management, L.P. | 48.3K | $310.4K | — | New |
| AMERICAN CENTURY COMPANIES INC | 48.1K | $309.5K | $48K | Added$246.4K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 42.3K | $272K | $117.6K | Added$117.6K |
| HSBC HOLDINGS PLC | 42.4K | $268.7K | — | New |
| EP Wealth Advisors, LLC | 41.2K | $264.7K | $114.4K | Added$114.4K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 40.9K | $262.9K | $58K | Added$186.6K |
| PIPER SANDLER & CO. | 39.5K | $253.8K | $109.7K | Added$109.7K |
| Invesco Ltd. | 36.9K | $237.5K | $78.5K | Added$134.4K |
| UBS Group AG | 36.3K | $233.3K | $36.7K | Added$185.1K |
| OMERS ADMINISTRATION Corp | 33.3K | $214.1K | $73.7K | Added$117.4K |
| Squarepoint Ops LLC | 31.2K | $200.4K | $86.6K | Cut−$36.1K |
| Dynamic Technology Lab Private Ltd | 29.6K | $190.3K | — | New |
| Vanguard Global Advisers, LLC | 26.3K | $169.1K | — | Held |
| RITHOLTZ WEALTH MANAGEMENT | 26K | $167.2K | $72.3K | Added$72.3K |
| Jump Financial, LLC | 24.7K | $158.7K | — | New |
| BENJAMIN EDWARDS INC | 23.4K | $150.5K | — | New |
| Mallini Complete Financial Planning LLC | 22.6K | $145.5K | $62.9K | Added$62.9K |
| CHOREO, LLC | 27.3K | $130.2K | $53.6K | Added$53.6K |
| Diametric Capital, LP | 18.4K | $118.5K | — | New |
| Catalyst Funds Management Pty Ltd | 17.9K | $115.1K | — | New |
| Engineers Gate Manager LP | 16.1K | $103.4K | $38K | Added$53.5K |
| Verdad Advisers, LP | 13.4K | $86K | — | New |
| Creative Planning | 12.3K | $79.3K | $34.3K | Added$34.3K |
| Quadrature Capital Ltd | 12.1K | $78K | — | New |
| Schonfeld Strategic Advisors LLC | 11.5K | $74.2K | — | New |
| T. Rowe Price Investment Management, Inc. | 9.87M | $63.4K | $3.77K | Added$58.5K |
| US BANCORP \DE\ | 8.01K | $51.5K | — | New |
| BNP PARIBAS FINANCIAL MARKETS | 5.64K | $36.3K | $1.5K | Added$34.3K |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.78M | $11.5K | $4.96K | Added$4.43K |
| ALGERT GLOBAL LLC | 286.1K | $1.84K | — | New |
| JPMORGAN CHASE & CO | 248 | $1.48K | $573 | Added$226 |
| ACADIAN ASSET MANAGEMENT LLC | 183.2K | $1.17K | $219 | Added$883 |
| HRT FINANCIAL LP | 90.7K | $583 | — | New |
| LBJ Family Wealth Advisors, Ltd. | 82.2K | $490 | $190 | Added$190 |
| Optiver Holding B.V. | 66 | $424 | $183 | Added$183 |
| SBI Securities Co., Ltd. | 50 | $322 | $139 | Cut−$14 |
| CWM, LLC | 39 | $251 | $251 | Added$251 |
| ROYAL BANK OF CANADA | 73 | $0 | $0 | Held |
Who left
Positions as of Q1 2026. 13F filings arrive up to 45 days after quarter-end and omit shorts. Values are quarter-end marks, as filed. Estimated mark is the price effect on shares still held — not realized P&L or investment advice.