| BAKER BROS. ADVISORS LP | 11M | $107.4M | — | Held |
| RTW INVESTMENTS, LP | 7.14M | $69.4M | — | Held |
| BlackRock, Inc. | 6.07M | $59M | — | Held |
| Vanguard | 3.78M | $36.7M | — | Held |
| State Street | 3.69M | $35.9M | — | Held |
| Fidelity | 2.98M | $29M | — | Held |
| FCPM III SERVICES B.V. | 2.81M | $27.3M | — | Held |
| D. E. Shaw & Co., Inc. | 2.58M | $25M | — | Held |
| TORONTO DOMINION BANK | 2.23M | $21.7M | — | Held |
| Erste Asset Management GmbH | 2.12M | $20.6M | — | Held |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.81M | $17.6M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 1.75M | $17M | — | Held |
| Commodore Capital LP | 1.43M | $13.9M | — | Held |
| Rosalind Advisors, Inc. | 1.41M | $13.7M | — | Held |
| ADAR1 Capital Management, LLC | 1.24M | $12.1M | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 1.12M | $10.9M | — | Held |
| Redmile Group, LLC | 1.1M | $10.7M | — | Held |
| JPMORGAN CHASE & CO | 925.2K | $8.99M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 834.6K | $8.11M | — | Held |
| MORGAN STANLEY | 814.9K | $7.92M | $4.51M | Added$2.16M |
| Boxer Capital Management, LLC | 750K | $7.29M | $4.15M | Added$2.89M |
| Jefferies Financial Group Inc. | 714.2K | $6.94M | — | Held |
| GOLDMAN SACHS GROUP INC | 658.1K | $6.4M | — | Held |
| Invesco Ltd. | 613K | $5.96M | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 606.8K | $5.9M | — | Held |
| UBS Group AG | 604.3K | $5.87M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 587.9K | $5.71M | — | Held |
| JANE STREET GROUP, LLC | 584.3K | $5.68M | — | Held |
| NAN FUNG TRINITY (HK) LTD | 575.5K | $5.59M | — | Held |
| Woodline Partners LP | 571K | $5.55M | — | Held |
| NORTHERN TRUST CORP | 539.6K | $5.24M | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 460.7K | $4.48M | — | Held |
| TWO SIGMA INVESTMENTS, LP | 444.1K | $4.32M | — | Held |
| Renaissance Technologies | 405.1K | $3.94M | — | Held |
| Quinn Opportunity Partners LLC | 392.9K | $3.82M | — | Held |
| Jump Financial, LLC | 296.8K | $2.89M | — | Held |
| BARCLAYS PLC | 292.2K | $2.84M | $1.62M | Added$930K |
| TD Asset Management Inc | 266.5K | $2.59M | — | Held |
| Omega Fund Management, LLC | 248.7K | $2.42M | — | Held |
| DIADEMA PARTNERS LP | 231K | $2.25M | — | Held |
| Caption Management, LLC | 228.6K | $2.22M | — | Held |
| BANK OF AMERICA CORP /DE/ | 215.3K | $2.09M | $604.3K | Added$1.64M |
| Bank of New York Mellon Corp | 209.2K | $2.03M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 208.7K | $2.03M | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 178.9K | $1.75M | — | Held |
| Trexquant Investment LP | 180.5K | $1.75M | — | Held |
| Resolute Capital Asset Partners LLC | 175K | $1.7M | — | Held |
| Citadel | 158.4K | $1.54M | — | Held |
| Hudson Bay Capital Management LP | 153.7K | $1.49M | — | New |
| AMERICAN CENTURY COMPANIES INC | 148.1K | $1.44M | — | Held |
| Rafferty Asset Management, LLC | 140.9K | $1.37M | — | Held |
| TUDOR INVESTMENT CORP ET AL | 128.4K | $1.25M | $114.8K | Added$1.16M |
| SummitTX Capital, L.P. | 108.8K | $1.06M | — | Held |
| MARSHALL WACE, LLP | 93.6K | $909.6K | — | Held |
| WELLS FARGO & COMPANY/MN | 90.7K | $881.8K | — | Held |
| RHUMBLINE ADVISERS | 89.3K | $868.1K | — | Held |
| Point72 Asset Management, L.P. | 72.2K | $701.9K | — | Held |
| Squarepoint Ops LLC | 67.3K | $653.9K | — | Held |
| Susquehanna Portfolio Strategies, LLC | 66.9K | $650K | — | Held |
| Nan Fung Group Holdings Ltd | 63.7K | $619.3K | — | Held |
| ALLIANCEBERNSTEIN L.P. | 62.1K | $604K | — | Held |
| ACT CAPITAL MANAGEMENT, LLC | 61.5K | $597.8K | — | Held |
| Persistent Asset Partners Ltd | 61.5K | $597.7K | — | New |
| Nuveen, LLC | 57.6K | $560K | — | Held |
| DEUTSCHE BANK AG\ | 53.9K | $524.3K | — | Held |
| Brevan Howard Capital Management LP | 53K | $514.8K | — | Held |
| PROFUND ADVISORS LLC | 52.1K | $506.8K | — | Held |
| NEOS Investment Management LLC | 52.1K | $505.9K | — | Held |
| TEMA ETFS LLC | 51.3K | $498.5K | — | Held |
| RAYMOND JAMES FINANCIAL INC | 47.4K | $460.4K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 44K | $451.5K | — | Held |
| Creative Planning | 45.2K | $439K | — | Held |
| Aquatic Capital Management LLC | 44.6K | $433.8K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 41.2K | $400.3K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 40.4K | $393K | — | Held |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 36K | $350.3K | — | Held |
| Schonfeld Strategic Advisors LLC | 35.2K | $342.3K | — | Held |
| OSAIC HOLDINGS, INC. | 35.2K | $342.1K | — | Held |
| MetLife Investment Management, LLC | 34.3K | $333.7K | — | Held |
| XTX Topco Ltd | 33.2K | $322.3K | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 32.1K | $311.9K | — | Held |
| TWO SIGMA ADVISERS, LP | 30.7K | $298.4K | — | Held |
| AlphaQuest LLC | 28.1K | $272.9K | — | Held |
| Virtus Investment Advisers, LLC | 26.1K | $254K | — | Held |
| Dynamic Technology Lab Private Ltd | 25.9K | $252K | — | Held |
| Balyasny Asset Management L.P. | 25.3K | $246.1K | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 24.7K | $240.1K | — | Held |
| Ballentine Partners, LLC | 23.7K | $230K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 21K | $203.7K | — | Held |
| CITIGROUP INC | 20.2K | $196.3K | — | Held |
| HighTower Advisors, LLC | 20.1K | $195.6K | — | Held |
| AXQ CAPITAL, LP | 19.9K | $193.1K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 18.4K | $179.3K | — | Held |
| 9823 Capital, L.P. | 18.3K | $178.2K | — | Held |
| Centiva Capital, LP | 18K | $175K | — | Held |
| INCEPTIONR LLC | 17.7K | $171.6K | — | Held |
| LPL Financial LLC | 17.1K | $166.4K | — | Held |
| GRIFFIN ASSET MANAGEMENT, INC. | 16.4K | $159.4K | — | Held |
| ProShare Advisors LLC | 16.1K | $156.6K | — | Held |
| J. Goldman & Co LP | 15.6K | $151.6K | — | Held |
| COMMONWEALTH EQUITY SERVICES, LLC | 15.4K | $149.8K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 15.2K | $147.9K | — | Held |
| Velan Capital Investment Management LP | 15K | $145.8K | — | Held |
| Quadrature Capital Ltd | 14.7K | $142.8K | — | Held |
| Graham Capital Management, L.P. | 14.4K | $139.6K | — | Held |
| HORIZON KINETICS ASSET MANAGEMENT LLC | 13.8K | $134.1K | — | Held |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 12.8K | $124.8K | — | Held |
| China Universal Asset Management Co., Ltd. | 12.8K | $124.2K | — | Held |
| AMERIPRISE FINANCIAL INC | 12.6K | $122.3K | — | Held |
| SIMPLEX TRADING, LLC | 12.4K | $120.1K | — | Held |
| Quantinno Capital Management LP | 12.3K | $119.4K | — | Held |
| HAMILTON CAPITAL PARTNERS, LLC | 11.5K | $111.7K | — | Held |
| Summit Financial, LLC | 11K | $107.3K | — | Held |
| LETKO, BROSSEAU & ASSOCIATES INC | 10.8K | $105K | — | Held |
| Entropy Technologies, LP | 10.5K | $101.9K | — | Held |
| Quadcap Wealth Management, LLC | 10K | $97.2K | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 8.26M | $80.3K | — | Held |
| Russell Investments Group, Ltd. | 8.12K | $78.9K | — | Held |
| Ameritas Investment Partners, Inc. | 6.17K | $59.9K | — | Held |
| Legal & General Group Plc | 6.01K | $58.4K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 4.26K | $41.4K | — | Held |
| Sterling Capital Management LLC | 4.1K | $39.9K | — | Held |
| Allworth Financial LP | 3.9K | $37.9K | $21.1K | Added$21.9K |
| Tower Research Capital LLC (TRC) | 3.84K | $37.3K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 3.81K | $37.1K | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 3.63K | $35.3K | — | Held |
| US BANCORP \DE\ | 3.14K | $30.5K | — | Held |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 3K | $29.2K | — | Held |
| ROYAL BANK OF CANADA | 2.3K | $22K | — | Held |
| SIGNATUREFD, LLC | 2.19K | $21.2K | — | Held |
| Steward Partners Investment Advisory, LLC | 2.06K | $20.1K | — | Held |
| Farther Finance Advisors, LLC | 2.06K | $20K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 1.54K | $15K | — | Held |
| SBI Securities Co., Ltd. | 1.01K | $9.85K | — | Held |
| COMERICA BANK | 787 | $7.65K | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 632 | $6.14K | — | Held |
| Clearstead Advisors, LLC | 500 | $4.86K | — | Held |
| GAMMA Investing LLC | 494 | $4.8K | — | Held |
| QUADRANT CAPITAL GROUP LLC | 392 | $3.81K | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 387 | $3.76K | — | Held |
| Optiver Holding B.V. | 313 | $3.04K | — | Held |
| HRT FINANCIAL LP | 253.6K | $2.46K | — | Held |
| Pinnacle Wealth Planning Services, Inc. | 137 | $1.33K | — | Held |
| PNC Financial Services Group, Inc. | 121 | $1.18K | — | Held |
| Physician Wealth Advisors, Inc. | 111 | $1.08K | — | Held |
| Parallel Advisors, LLC | 105 | $1.02K | — | Held |
| EverSource Wealth Advisors, LLC | 100 | $972 | — | Held |
| Larson Financial Group LLC | 100 | $972 | — | Held |
| HUNTINGTON NATIONAL BANK | 92 | $894 | — | Held |
| Sound Income Strategies, LLC | 125 | $880 | — | Held |
| Smartleaf Asset Management LLC | 80 | $786 | — | Held |
| SG Americas Securities, LLC | 72K | $699 | — | Held |
| Parkside Financial Bank & Trust | 60 | $584 | — | Held |
| ACADIAN ASSET MANAGEMENT LLC | 56.7K | $550 | — | Held |
| GSA CAPITAL PARTNERS LLP | 29.1K | $283 | — | Held |
| Arax Advisory Partners | 19 | $185 | — | Held |
| MAI Capital Management | 19 | $185 | — | Held |
| ROTHSCHILD INVESTMENT LLC | 9 | $87 | — | Held |
| VESTOR CAPITAL, LLC | 400 | $43 | — | Held |
| CWM, LLC | 4.05K | $39 | — | Held |
| AMALGAMATED BANK | 2.17K | $21 | — | Held |
| CoreCap Advisors, LLC | 2 | $19 | — | Held |
| Essential Partners LLC | 1 | $10 | $6 | Added$6 |
| Daiwa Securities Group Inc. | 200 | $2 | — | Held |
| Covestor Ltd | 10 | $0 | — | Held |
| BESSEMER GROUP INC | 0 | $0 | — | Held |