| JPMORGAN CHASE & CO | 12.9M | $2.94B | — | Held |
| Vanguard | 12.3M | $2.82B | — | Held |
| BlackRock, Inc. | 10.9M | $2.49B | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 4.98M | $1.14B | — | Held |
| FARALLON CAPITAL MANAGEMENT LLC | 3.91M | $896.7M | $266.6M | Added$212.1M |
| State Street | 3.23M | $739M | — | Held |
| Coatue | 2.63M | $603.3M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 2.61M | $596.1M | — | Held |
| Icahn Capital | 2.6M | $595.5M | — | Held |
| FRANKLIN RESOURCES INC | 2.53M | $580.6M | — | Held |
| Castle Hook Partners LP | 2.17M | $496.6M | — | Held |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 2.05M | $469.2M | — | Held |
| FRED ALGER MANAGEMENT, LLC | 1.82M | $417.5M | — | Held |
| NORGES BANK | 1.63M | $372.4M | $125.5M | Added$169.9M |
| Sofinnova Investments, Inc. | 1.55M | $355.2M | — | Held |
| RTW INVESTMENTS, LP | 1.5M | $343.6M | — | Held |
| Fidelity | 1.48M | $338.1M | — | Held |
| Capital World Investors | 1.43M | $328.3M | — | Held |
| Invesco Ltd. | 1.33M | $304.5M | — | Held |
| MORGAN STANLEY | 1.23M | $282.7M | $84.1M | Added$76.2M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1.18M | $270.3M | — | Held |
| FEDERATED HERMES, INC. | 1.02M | $233.5M | — | Held |
| MAVERICK CAPITAL LTD | 944K | $216.3M | — | Held |
| BANK OF AMERICA CORP /DE/ | 875.4K | $200.5M | $51.9M | Added$78M |
| GILDER GAGNON HOWE & CO LLC | 828.3K | $189.8M | — | Held |
| Clearbridge Investments, LLC | 790.1K | $181M | — | Held |
| NORTHERN TRUST CORP | 775.8K | $177.7M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 741.7K | $169.9M | — | Held |
| ARK Investment Management LLC | 731.1K | $167.5M | — | Held |
| GOLDMAN SACHS GROUP INC | 716.8K | $164.2M | — | Held |
| PointState Capital LP | 715.5K | $163.9M | — | Held |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 714.7K | $163.7M | — | Held |
| Sumitomo Mitsui Trust Group, Inc. | 711.4K | $163M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 674.4K | $154.5M | — | Held |
| Bank of New York Mellon Corp | 652.9K | $149.6M | — | Held |
| Driehaus Capital Management LLC | 625.9K | $143.4M | — | Held |
| RAYMOND JAMES FINANCIAL INC | 614.2K | $141.1M | — | Held |
| Chevy Chase Trust Holdings, LLC | 582K | $133.3M | — | Held |
| VICTORY CAPITAL MANAGEMENT INC | 556.7K | $127.5M | — | Held |
| D. E. Shaw & Co., Inc. | 553.6K | $126.8M | — | Held |
| AMERICAN CENTURY COMPANIES INC | 540.7K | $123.9M | — | Held |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 521.8K | $119.5M | — | Held |
| Nuveen, LLC | 479.2K | $109.8M | — | Held |
| AGF MANAGEMENT LTD | 474.1K | $108.6M | — | Held |
| Amova Asset Management Americas, Inc. | 471.1K | $107.8M | — | Held |
| Allspring Global Investments Holdings, LLC | 454.5K | $104M | — | Held |
| UBS Group AG | 438.9K | $100.5M | — | Held |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 407.7K | $93.4M | — | Held |
| PANAGORA ASSET MANAGEMENT INC | 393.4K | $90.1M | — | Held |
| WELLS FARGO & COMPANY/MN | 384.8K | $88.1M | — | Held |
| Qube Research & Technologies Ltd | 367.9K | $84.3M | — | Held |
| ORBIMED ADVISORS LLC | 365.8K | $83.8M | — | Held |
| Legal & General Group Plc | 363.1K | $83.2M | — | Held |
| Swiss National Bank | 357.2K | $81.8M | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 350.9K | $80.4M | — | Held |
| Robeco Institutional Asset Management B.V. | 343.8K | $78.8M | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 336.5K | $77.1M | — | Held |
| AMERIPRISE FINANCIAL INC | 335.3K | $76.8M | — | Held |
| Eversept Partners, LP | 334.5K | $76.6M | — | Held |
| Amundi | 333.2K | $76.3M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 332.2K | $76.1M | — | Held |
| ZEVENBERGEN CAPITAL INVESTMENTS LLC | 323.6K | $74.1M | — | Held |
| FIRST TRUST ADVISORS LP | 319.7K | $73.2M | — | Held |
| PRINCIPAL FINANCIAL GROUP INC | 319.5K | $73.2M | — | Held |
| TWO SIGMA ADVISERS, LP | 307.7K | $70.5M | — | Held |
| DEUTSCHE BANK AG\ | 284.5K | $65.2M | — | Held |
| Kinetic Partners Management, LP | 273.3K | $62.6M | — | Held |
| TUDOR INVESTMENT CORP ET AL | 271.4K | $62.2M | $1.31M | Added$59.1M |
| TWO SIGMA INVESTMENTS, LP | 267.2K | $61.2M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 245.1K | $56.1M | — | Held |
| ROYAL BANK OF CANADA | 244K | $55.9M | — | Held |
| Rokos Capital Management LLP | 242.9K | $55.6M | — | Held |
| Civilization Ventures Management, LLC | 228.5K | $52.3M | — | Held |
| California Public Employees Retirement System | 223.5K | $51.2M | — | Held |
| NOMURA ASSET MANAGEMENT CO LTD | 218.2K | $50M | — | Held |
| National Pension Service | 217.8K | $49.9M | — | Held |
| IEQ CAPITAL, LLC | 209.8K | $48.1M | — | Held |
| ENVESTNET ASSET MANAGEMENT INC | 205.9K | $47.2M | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 201.9K | $46.3M | — | Held |
| NEUBERGER BERMAN GROUP LLC | 197.1K | $45.1M | — | Held |
| JENNISON ASSOCIATES LLC | 195.9K | $44.9M | — | Held |
| AustralianSuper Pty Ltd | 195.4K | $44.8M | — | Held |
| Renaissance Technologies | 190.6K | $43.7M | — | Held |
| Eagle Health Investments LP | 183.3K | $42M | — | Held |
| Capital Impact Advisors, LLC | 178.6K | $40.9M | — | Held |
| SEI INVESTMENTS CO | 176.3K | $40.4M | — | Held |
| RHUMBLINE ADVISERS | 166.1K | $38.1M | — | Held |
| CIBC Private Wealth Group LLC | 163.5K | $37.5M | — | Held |
| TD Asset Management Inc | 157.5K | $36.1M | — | Held |
| Mitsubishi UFJ Asset Management Co., Ltd. | 157.6K | $36.1M | — | Held |
| Ensign Peak Advisors, Inc | 153.3K | $35.1M | — | Held |
| Artemis Investment Management LLP | 153.3K | $35.1M | — | Held |
| BARCLAYS PLC | 152.9K | $35M | $10.4M | Added$5.26M |
| WORLDQUANT MILLENNIUM ADVISORS LLC | 149.2K | $34.2M | — | Held |
| LOOMIS SAYLES & CO L P | 145.6K | $33.4M | — | Held |
| LPL Financial LLC | 144.2K | $33M | — | Held |
| Blue Water Life Science Advisors, LP | 141.5K | $32.4M | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 139.9K | $32.1M | — | Held |
| Zweig-DiMenna Associates LLC | 134.8K | $30.9M | — | Held |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 131.7K | $30.2M | — | Held |
| CITIGROUP INC | 130.3K | $29.9M | — | Held |
| Erste Asset Management GmbH | 126.5K | $29M | — | Held |
| Jump Financial, LLC | 125.7K | $28.8M | — | Held |
| Point72 Asset Management, L.P. | 125.3K | $28.7M | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 122.8K | $28.1M | — | Held |
| Ilex Capital Partners (UK) LLP | 117.7K | $27M | — | Held |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 115.7K | $26.5M | — | Held |
| Cerity Partners LLC | 115.3K | $26.4M | — | Held |
| BRAIDWELL LP | 111.5K | $25.5M | — | Held |
| Citadel | 109.9K | $25.2M | — | Held |
| SAMLYN CAPITAL, LLC | 108K | $24.7M | — | Held |
| HSBC HOLDINGS PLC | 105K | $24.2M | — | Held |
| Candriam S.C.A. | 99.1K | $22.7M | — | Held |
| AVIVA PLC | 98.7K | $22.6M | — | Held |
| MPM BIOIMPACT LLC | 93.6K | $21.4M | — | Held |
| GROUPAMA ASSET MANAGMENT | 92.3K | $21.1M | $5.26M | Added$8.71M |
| PICTON MAHONEY ASSET MANAGEMENT | 92.1K | $21.1M | — | Held |
| PARADIGM CAPITAL MANAGEMENT INC/NY | 90.4K | $20.7M | — | Held |
| Skandinaviska Enskilda Banken AB (publ) | 82.1K | $18.8M | — | Held |
| Gotham Asset Management, LLC | 81.3K | $18.6M | — | Held |
| First Turn Management, LLC | 80.9K | $18.5M | — | Held |
| JAG CAPITAL MANAGEMENT, LLC | 80.8K | $18.5M | — | Held |
| Russell Investments Group, Ltd. | 80.2K | $18.4M | — | Held |
| Lagoda Investment Management, L.P. | 79.3K | $18.2M | — | Held |
| Science & Technology Partners, L.P. | 79.3K | $18.2M | — | Held |
| Davern Capital Partners, LP | 78.7K | $18M | — | Held |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 78.5K | $18M | — | Held |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 78.3K | $17.9M | — | New |
| Mariner, LLC | 78.1K | $17.9M | — | Held |
| HighTower Advisors, LLC | 75.9K | $17.4M | — | Held |
| GDS Wealth Management | 73.3K | $16.8M | — | Held |
| Allianz Asset Management GmbH | 72.6K | $16.6M | — | Held |
| Sterling Capital Management LLC | 71.2K | $16.3M | — | Held |
| PARNASSUS INVESTMENTS, LLC | 70.8K | $16.2M | — | Held |
| JANE STREET GROUP, LLC | 70.7K | $16.2M | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 67.8K | $15.5M | — | Held |
| Foresite Capital Management VI LLC | 67.4K | $15.4M | — | Held |
| Foresite Capital Management V, LLC | 67.4K | $15.4M | — | Held |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 66.6K | $15.3M | — | Held |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 65.7K | $15.1M | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 65.7K | $15.1M | — | Held |
| MERCER GLOBAL ADVISORS INC /ADV | 62.8K | $14.4M | — | Held |
| Catalio Capital Management, LP | 62.3K | $14.3M | — | Held |
| Trexquant Investment LP | 60.9K | $13.9M | — | Held |
| Walleye Capital LLC | 60.4K | $13.8M | — | Held |
| Jain Global LLC | 58.6K | $13.4M | — | Held |
| Engineers Gate Manager LP | 57.5K | $13.2M | — | Held |
| DANSKE BANK A/S | 57K | $13.1M | $3.1M | Added$4.34M |
| Robinhood Asset Management, LLC | 56.7K | $13M | — | Held |
| Quantinno Capital Management LP | 56.5K | $13M | — | Held |
| Bellevue Group AG | 56K | $12.8M | — | Held |
| Verition Fund Management LLC | 55.8K | $12.8M | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 55.5K | $12.8M | — | Held |
| CAPITAL FUND MANAGEMENT S.A. | 52.2K | $12M | — | Held |
| Mitsubishi UFJ Trust & Banking Corp | 52.2K | $11.9M | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 51.9K | $11.9M | — | Held |
| TRUIST FINANCIAL CORP | 51.5K | $11.8M | — | Held |
| Pictet Asset Management Holding SA | 50.9K | $11.7M | — | Held |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 45.8K | $11.5M | — | Held |
| Systrade AG | 50K | $11.5M | — | Held |
| KORNITZER CAPITAL MANAGEMENT INC /KS | 49.9K | $11.4M | — | Held |
| Asset Management One Co., Ltd. | 49.3K | $11.4M | — | Held |
| GCM Grosvenor Holdings, LLC | 49.7K | $11.4M | — | Held |
| CI INVESTMENTS INC. | 49K | $11.2M | — | Held |
| KLP KAPITALFORVALTNING AS | 48.2K | $11M | — | Held |
| Swedbank AB | 48.2K | $11M | — | Held |
| STRS OHIO | 47.5K | $10.9M | — | Held |
| EFG International AG | 46.8K | $10.7M | — | Held |
| BANK OF MONTREAL /CAN/ | 45.6K | $10.4M | — | Held |
| Korea Investment CORP | 45.4K | $10.4M | — | Held |
| State of New Jersey Common Pension Fund D | 44.8K | $10.3M | — | Held |
| PERKINS CAPITAL MANAGEMENT INC | 44.5K | $10.2M | — | Held |
| Assenagon Asset Management S.A. | 44.4K | $10.2M | — | Held |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 42.8K | $9.8M | — | Held |
| PINNBROOK CAPITAL MANAGEMENT LP | 41.9K | $9.59M | — | Held |
| Rhenman & Partners Asset Management AB | 40.5K | $9.28M | — | Held |
| Lansforsakringar Fondforvaltning AB (publ) | 40.4K | $9.27M | — | Held |
| DEEPWATER ASSET MANAGEMENT, LLC | 39.6K | $9.08M | — | Held |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 39.1K | $8.95M | — | Held |
| Resona Asset Management Co.,Ltd. | 37.7K | $8.65M | — | Held |
| Artisan Partners Limited Partnership | 37.4K | $8.57M | — | Held |
| Schonfeld Strategic Advisors LLC | 37K | $8.48M | — | Held |
| CREDIT AGRICOLE S A | 36.8K | $8.43M | — | Held |
| Caisse de depot et placement du Quebec | 36.4K | $8.33M | — | Held |
| Meridiem Capital Partners LP | 36K | $8.25M | — | Held |
| Creative Planning | 35.9K | $8.22M | — | Held |
| ARIZONA STATE RETIREMENT SYSTEM | 35.7K | $8.17M | — | Held |
| Brevan Howard Capital Management LP | 35.3K | $8.16M | — | Held |
| STIFEL FINANCIAL CORP | 35.4K | $8.11M | — | Held |
| Voleon Capital Management LP | 32.7K | $7.48M | — | Held |
| MEEDER ASSET MANAGEMENT INC | 31.9K | $7.31M | — | Held |
| FJARDE AP-FONDEN /FOURTH SWEDISH NATIONAL PENSION FUND | 31.8K | $7.29M | — | Held |
| OP Asset Management Ltd | 31.5K | $7.21M | $1.85M | Added$2.83M |
| Board of Trustees of The Leland Stanford Junior University | 31.3K | $7.17M | — | Held |
| Vestmark Advisory Solutions, Inc. | 30.2K | $6.93M | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 29.9K | $6.85M | — | Held |
| E. Ohman J:or Asset Management AB | 29.8K | $6.83M | — | Held |
| SWS Partners | 29K | $6.64M | — | Held |
| Andra AP-fonden | 28.2K | $6.46M | — | Held |
| FORSTA AP-FONDEN | 27.7K | $6.35M | — | Held |
| XPONANCE LLC | 27.2K | $6.23M | — | Held |
| STOREBRAND ASSET MANAGEMENT AS | 26.4K | $6.04M | — | Held |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 26.1K | $5.97M | — | Held |
| Graham Capital Management, L.P. | 25.7K | $5.9M | — | Held |
| Cetera Investment Advisers | 25K | $5.72M | — | Held |
| Rafferty Asset Management, LLC | 25K | $5.72M | — | Held |
| Man Group plc | 24.9K | $5.7M | — | Held |
| COMERICA BANK | 24.8K | $5.68M | — | Held |
| DNB Asset Management AS | 24.8K | $5.68M | — | Held |
| OSAIC HOLDINGS, INC. | 24.6K | $5.64M | — | Held |
| Pathstone Holdings, LLC | 23.8K | $5.44M | — | Held |
| BEACONLIGHT CAPITAL, LLC | 23.3K | $5.33M | — | Held |
| BRITISH COLUMBIA INVESTMENT MANAGEMENT Corp | 23.1K | $5.29M | — | Held |
| Banco Santander, S.A. | 23K | $5.27M | — | New |
| Mesirow Financial Investment Management, Inc. | 22.9K | $5.26M | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 22.4K | $5.14M | — | Held |
| Faithward Advisors, LLC | 22.1K | $5.07M | — | Held |
| SeaBridge Investment Advisors LLC | 21.8K | $4.99M | — | Held |
| Utah Retirement Systems | 21.4K | $4.91M | — | Held |
| Aubrey Capital Management Ltd | 21.4K | $4.9M | — | Held |
| TORONTO DOMINION BANK | 21.1K | $4.83M | — | Held |
| Entropy Technologies, LP | 20.2K | $4.63M | — | Held |
| Soleus Capital Management, L.P. | 20K | $4.58M | — | Held |
| Police & Firemen's Retirement System of New Jersey | 19.9K | $4.56M | — | Held |
| GUGGENHEIM CAPITAL LLC | 19.6K | $4.49M | — | Held |
| CAPTRUST FINANCIAL ADVISORS | 19.6K | $4.49M | — | Held |
| Nicholas Investment Partners, LP | 19.4K | $4.43M | — | Held |
| Pinnacle Financial Partners, Inc. | 19.3K | $4.43M | — | Held |
| Merit Financial Group, LLC | 18.7K | $4.29M | — | Held |
| Exome Asset Management LLC | 18.6K | $4.27M | — | Held |
| ASSETMARK, INC | 17.4K | $3.99M | — | Held |
| Leeward Financial Partners, LLC | 17.3K | $3.97M | — | Held |
| Focus Partners Wealth | 17.2K | $3.93M | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 17K | $3.9M | — | Held |
| OpenArc Corporate Advisory, LLC | 17K | $3.9M | — | Held |
| Rockingstone Advisors LLC | 17K | $3.9M | — | Held |
| BANK OF HAWAII | 16.7K | $3.83M | — | Held |
| NISSAY ASSET MANAGEMENT CORP /JAPAN | 16.6K | $3.79M | — | Held |
| Elo Mutual Pension Insurance Co | 16.4K | $3.76M | — | Held |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 16.3K | $3.73M | — | Held |
| SALEM INVESTMENT COUNSELORS INC | 16.3K | $3.73M | — | Held |
| Sanctuary Advisors, LLC | 15.9K | $3.64M | $941.2K | Added$1.42M |
| Guided Capital Wealth Management, LLC | 15.8K | $3.62M | — | Held |
| Portolan Capital Management, LLC | 15.6K | $3.57M | — | Held |
| BRANDYWINE MANAGERS, LLC | 15.6K | $3.57M | — | Held |
| Silvant Capital Management LLC | 15.5K | $3.56M | — | Held |
| Advisors Asset Management, Inc. | 15.5K | $3.54M | — | Held |
| Chicago Capital, LLC | 15.1K | $3.45M | — | Held |
| Keebeck Wealth Management | 14.9K | $3.41M | — | Held |
| NIA IMPACT ADVISORS, LLC | 14.9K | $3.41M | — | Held |