| Polar Capital Holdings Plc | 2.88M | $44.4M | — | Held |
| Soleus Capital Management, L.P. | 2.7M | $41.7M | — | Held |
| MORGAN STANLEY | 2.55M | $39.3M | $13.1M | Added$13.1M |
| ORBIMED ADVISORS LLC | 2.41M | $37.2M | — | Held |
| BlackRock, Inc. | 2.38M | $36.8M | — | Held |
| Driehaus Capital Management LLC | 1.51M | $23.3M | — | Held |
| Vanguard | 1.48M | $22.9M | — | Held |
| First Light Asset Management, LLC | 1.35M | $20.8M | — | Held |
| DEUTSCHE BANK AG\ | 929.5K | $14.4M | — | Held |
| ARMISTICE CAPITAL, LLC | 792K | $12.2M | — | Held |
| KOTLER KEVIN | 631.5K | $9.75M | — | Held |
| Fidelity | 624.9K | $9.65M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 596.2K | $9.21M | — | Held |
| State Street | 447.9K | $6.92M | — | Held |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 396.6K | $6.12M | — | Held |
| Nantahala Capital Management, LLC | 295.1K | $4.56M | — | Held |
| NORTHERN TRUST CORP | 231.8K | $3.58M | — | Held |
| Walleye Capital LLC | 228.8K | $3.53M | — | Held |
| Renaissance Technologies | 222.3K | $3.43M | — | Held |
| Palumbo Wealth Management LLC | 214.2K | $3.31M | — | Held |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 213.9K | $3.3M | — | Held |
| Qube Research & Technologies Ltd | 199K | $3.07M | — | Held |
| TUDOR INVESTMENT CORP ET AL | 193.3K | $2.99M | $788.5K | Added$1.4M |
| BANK OF AMERICA CORP /DE/ | 170.4K | $2.63M | $295.9K | Added$2.04M |
| GOLDMAN SACHS GROUP INC | 164.7K | $2.54M | — | Held |
| Citadel | 131.9K | $2.04M | — | Held |
| JPMORGAN CHASE & CO | 130.9K | $2.02M | — | Held |
| JANE STREET GROUP, LLC | 117.6K | $1.82M | — | Held |
| LAZARD ASSET MANAGEMENT LLC | 113.2K | $1.75M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 93.7K | $1.45M | — | Held |
| Nuveen, LLC | 92.8K | $1.43M | — | Held |
| SEI INVESTMENTS CO | 80.2K | $1.24M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 76.2K | $1.18M | — | Held |
| Informed Momentum Co LLC | 75.8K | $1.17M | — | Held |
| Russell Investments Group, Ltd. | 73.7K | $1.14M | — | Held |
| Legato Capital Management LLC | 69.2K | $1.07M | — | Held |
| BARCLAYS PLC | 68.6K | $1.06M | $333.4K | Added$388.4K |
| TWO SIGMA INVESTMENTS, LP | 68.1K | $1.05M | — | Held |
| HighMark Wealth Management LLC | 63K | $972.7K | — | Held |
| PRINCIPAL FINANCIAL GROUP INC | 58.4K | $902K | — | Held |
| Connor, Clark & Lunn Investment Management Ltd. | 58.3K | $899.5K | — | Held |
| PANAGORA ASSET MANAGEMENT INC | 58K | $895.6K | — | Held |
| Bank of New York Mellon Corp | 53.8K | $831.4K | — | Held |
| TWO SIGMA ADVISERS, LP | 51.1K | $789K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 46.9K | $724.4K | — | Held |
| UBS Group AG | 44.9K | $693.5K | — | Held |
| Trexquant Investment LP | 39.2K | $604.6K | — | Held |
| HSBC HOLDINGS PLC | 37.6K | $579K | — | Held |
| XTX Topco Ltd | 34K | $524.6K | — | Held |
| WELLS FARGO & COMPANY/MN | 33.1K | $510.9K | — | Held |
| ExodusPoint Capital Management, LP | 31.8K | $491K | — | Held |
| MARSHALL WACE, LLP | 31K | $479.1K | — | Held |
| RHUMBLINE ADVISERS | 29.3K | $452.5K | — | Held |
| Numerai GP LLC | 29.3K | $452K | — | Held |
| Squarepoint Ops LLC | 28K | $432.6K | — | Held |
| Jump Financial, LLC | 25.7K | $396.8K | — | Held |
| Point72 Asset Management, L.P. | 24.6K | $380.5K | — | Held |
| Western Wealth Management, LLC | 22.9K | $354.3K | — | Held |
| Man Group plc | 21.6K | $333.9K | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 20.2K | $311.9K | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 17.8K | $275.6K | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 26.8K | $264.4K | — | Held |
| ROYAL BANK OF CANADA | 15.5K | $239K | — | Held |
| MetLife Investment Management, LLC | 15.3K | $236K | — | Held |
| Engineers Gate Manager LP | 12.2K | $187.6K | — | Held |
| EntryPoint Capital, LLC | 12K | $184.6K | — | Held |
| Invesco Ltd. | 11.9K | $184.3K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 11.9K | $183K | — | Held |
| PharVision Advisers, LLC | 11.7K | $180.6K | — | Held |
| PFM Health Sciences, LP | 11.3K | $174.9K | — | Held |
| Aquatic Capital Management LLC | 10.4K | $160.7K | — | Held |
| Brevan Howard Capital Management LP | 10.2K | $157.3K | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 10.1K | $156.3K | — | Held |
| AlphaQuest LLC | 8.95K | $138.2K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 7.7K | $118.9K | — | Held |
| Mitsubishi UFJ Asset Management Co., Ltd. | 7.66K | $116.2K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 6.37K | $98.4K | — | Held |
| Legal & General Group Plc | 2.6K | $40.2K | — | Held |
| Tower Research Capital LLC (TRC) | 2.52K | $38.8K | — | Held |
| Ameritas Investment Partners, Inc. | 2.46K | $37.9K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1.57K | $24.2K | — | Held |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 1.2K | $18.5K | — | Held |
| Quarry LP | 790 | $12.2K | — | Held |
| Kemnay Advisory Services Inc. | 653 | $10.1K | — | Held |
| CITIGROUP INC | 576 | $8.89K | — | Held |
| Optiver Holding B.V. | 270 | $4.17K | — | Held |
| ALGERT GLOBAL LLC | 172.9K | $2.67K | — | Held |
| Sterling Capital Management LLC | 156 | $2.41K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 53 | $818 | — | Held |
| GSA CAPITAL PARTNERS LLP | 29.9K | $462 | — | Held |
| Sound Income Strategies, LLC | 21 | $356 | — | Held |
| SBI Securities Co., Ltd. | 20 | $309 | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 14.8K | $230 | — | Held |
| Hughes Financial Services, LLC | 14 | $216 | — | Held |
| Larson Financial Group LLC | 11 | $170 | — | Held |
| GAMMA Investing LLC | 9 | $139 | — | Held |
| SG Americas Securities, LLC | 7.61K | $118 | — | Held |
| ACADIAN ASSET MANAGEMENT LLC | 3.25K | $49 | — | Held |
| AMALGAMATED BANK | 800 | $12 | — | Held |
| CWM, LLC | 156 | $2 | — | Held |