| BAKER BROS. ADVISORS LP | 2.14M | $1.25B | — | Held |
| RTW INVESTMENTS, LP | 1.99M | $1.16B | — | Held |
| Vanguard | 1.81M | $1.05B | — | Held |
| Avoro Capital Advisors LLC | 1.81M | $1.05B | — | Held |
| PAULSON & CO. INC. | 1.71M | $994.4M | — | Held |
| BlackRock, Inc. | 1.64M | $957.8M | — | Held |
| JANUS HENDERSON GROUP PLC | 1.58M | $918.2M | — | Held |
| State Street | 583K | $339.5M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 461.4K | $268.7M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 451.7K | $263.1M | — | Held |
| Fidelity | 439.4K | $255.9M | — | Held |
| BANK OF AMERICA CORP /DE/ | 416K | $242.3M | $30.2M | Added$130.2M |
| Invesco Ltd. | 365.3K | $212.7M | — | Held |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 354.2K | $206.3M | — | Held |
| GOLDMAN SACHS GROUP INC | 305.8K | $178.1M | — | Held |
| Polar Capital Holdings Plc | 270.2K | $157.3M | — | Held |
| ARMISTICE CAPITAL, LLC | 265.7K | $154.7M | — | Held |
| Hood River Capital Management LLC | 247.6K | $144.2M | — | Held |
| ALKEON CAPITAL MANAGEMENT LLC | 240K | $139.8M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 219.1K | $127.6M | — | Held |
| Artisan Partners Limited Partnership | 198.7K | $115.7M | — | Held |
| NORGES BANK | 196.4K | $114.4M | $23.6M | Added$83.2M |
| DEUTSCHE BANK AG\ | 192.1K | $111.9M | — | Held |
| AMERICAN CENTURY COMPANIES INC | 185.1K | $107.8M | — | Held |
| Pictet Asset Management Holding SA | 181.9K | $106M | — | Held |
| Fiera Capital Corp | 169.5K | $98.7M | — | Held |
| NORTHERN TRUST CORP | 151.8K | $88.4M | — | Held |
| MORGAN STANLEY | 150.5K | $87.6M | $18.6M | Cut−$26.9M |
| Erste Asset Management GmbH | 141.1K | $82.3M | — | Held |
| Rock Springs Capital Management LP | 139.6K | $81.3M | — | Held |
| Bank of New York Mellon Corp | 136.9K | $79.7M | — | Held |
| Point72 Asset Management, L.P. | 126.4K | $73.6M | — | Held |
| Woodline Partners LP | 125.7K | $73.2M | — | Held |
| Nuveen, LLC | 118.4K | $68.9M | — | Held |
| Driehaus Capital Management LLC | 111.7K | $65M | — | Held |
| UBS Group AG | 102.6K | $59.8M | — | Held |
| MPM BIOIMPACT LLC | 96.8K | $56.4M | — | Held |
| JANE STREET GROUP, LLC | 93.1K | $54.2M | — | Held |
| D. E. Shaw & Co., Inc. | 88.6K | $51.6M | — | Held |
| FRANKLIN RESOURCES INC | 86.1K | $50.1M | — | Held |
| Tri Locum Partners LP | 86K | $50.1M | — | Held |
| Renaissance Technologies | 83.9K | $48.8M | — | Held |
| ArrowMark Colorado Holdings LLC | 82.6K | $48.1M | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 75.9K | $44.2M | — | Held |
| Squarepoint Ops LLC | 74.9K | $43.6M | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 73.7K | $42.9M | — | Held |
| First Light Asset Management, LLC | 66.8K | $38.9M | — | Held |
| RAYMOND JAMES FINANCIAL INC | 66.7K | $38.9M | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 64.5K | $37.5M | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 64.3K | $37.4M | — | Held |
| Candriam S.C.A. | 63.9K | $37.2M | — | Held |
| Connor, Clark & Lunn Investment Management Ltd. | 58.3K | $33.9M | — | Held |
| Jain Global LLC | 52.7K | $30.7M | — | Held |
| Ensign Peak Advisors, Inc | 51K | $29.7M | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 50.6K | $29.5M | — | Held |
| EULAV Asset Management | 49K | $28.5M | — | Held |
| Russell Investments Group, Ltd. | 48.2K | $28M | — | Held |
| CANADA PENSION PLAN INVESTMENT BOARD | 46.1K | $26.9M | — | Held |
| WELLS FARGO & COMPANY/MN | 43.5K | $25.3M | — | Held |
| JPMORGAN CHASE & CO | 40.1K | $23.3M | — | Held |
| MARSHALL WACE, LLP | 39.6K | $23M | — | Held |
| EMERALD ADVISERS, LLC | 38.9K | $22.7M | — | Held |
| BARCLAYS PLC | 38.7K | $22.5M | $4.79M | Cut−$344.4K |
| Citadel | 36.1K | $21M | — | Held |
| Atika Capital Management LLC | 34K | $19.8M | — | Held |
| SEGALL BRYANT & HAMILL, LLC | 33.5K | $19.5M | — | Held |
| GILDER GAGNON HOWE & CO LLC | 33.5K | $19.5M | — | Held |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 32.9K | $19.1M | — | Held |
| California Public Employees Retirement System | 31.3K | $18.2M | — | Held |
| Affinity Asset Advisors, LLC | 31.1K | $18.1M | — | Held |
| GROUPAMA ASSET MANAGMENT | 30.6K | $17.8M | $3.39M | Added$5.24M |
| AMERIPRISE FINANCIAL INC | 29.3K | $17.1M | — | Held |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 29.1K | $17M | — | Held |
| Swiss National Bank | 28.6K | $16.6M | — | Held |
| STEADFAST CAPITAL MANAGEMENT LP | 26.9K | $15.6M | — | Held |
| EMERALD MUTUAL FUND ADVISERS TRUST | 25K | $14.6M | — | Held |
| FIRST TRUST ADVISORS LP | 24.8K | $14.5M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 23.8K | $13.9M | — | Held |
| RHUMBLINE ADVISERS | 23.7K | $13.8M | — | Held |
| CITIGROUP INC | 23.3K | $13.6M | — | Held |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 23.2K | $13.5M | — | Held |
| SEI INVESTMENTS CO | 23.1K | $13.4M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 21.9K | $12.8M | — | Held |
| Tao Capital Management LP | 21K | $12.2M | — | Held |
| Rockefeller Capital Management L.P. | 19.7K | $11.4M | — | Held |
| Rhenman & Partners Asset Management AB | 19.6K | $11.4M | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 19.3K | $11.3M | — | Held |
| Jump Financial, LLC | 19.2K | $11.2M | — | Held |
| Bridgewater | 19.2K | $11.2M | — | Held |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 19.1K | $11.1M | — | Held |
| NEUBERGER BERMAN GROUP LLC | 18.7K | $10.9M | — | Held |
| STEMPOINT CAPITAL LP | 17.7K | $10.3M | — | Held |
| WCM INVESTMENT MANAGEMENT, LLC | 17.3K | $10.1M | — | Held |
| LPL Financial LLC | 16.5K | $9.63M | — | Held |
| FEDERATED HERMES, INC. | 16.3K | $9.51M | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 16.1K | $9.36M | — | Held |
| ENVESTNET ASSET MANAGEMENT INC | 15.4K | $8.95M | — | Held |
| Legal & General Group Plc | 15.2K | $8.87M | — | Held |
| Man Group plc | 14.8K | $8.6M | — | Held |
| CASTLEARK MANAGEMENT LLC | 14.5K | $8.42M | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 14K | $8.16M | — | Held |
| Skandinaviska Enskilda Banken AB (publ) | 13.4K | $7.84M | — | Held |
| Informed Momentum Co LLC | 12.8K | $7.48M | — | Held |
| JOURNEY STRATEGIC WEALTH LLC | 12.8K | $7.47M | — | Held |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 12.1K | $7.05M | — | Held |
| IMC-Chicago, LLC | 12.1K | $7.02M | — | Held |
| Nan Fung Group Holdings Ltd | 11.9K | $6.91M | — | Held |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 11.6K | $6.75M | — | Held |
| Voleon Capital Management LP | 11.2K | $6.54M | — | Held |
| Creative Planning | 11.1K | $6.49M | — | Held |
| Resolute Capital Asset Partners LLC | 10.9K | $6.36M | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 10.6K | $6.15M | — | Held |
| Rafferty Asset Management, LLC | 10.5K | $6.13M | — | Held |
| EFG International AG | 10.4K | $6.05M | — | Held |
| TD Asset Management Inc | 10.4K | $6.05M | — | Held |
| MetLife Investment Management, LLC | 10.2K | $5.96M | — | Held |
| ROYAL BANK OF CANADA | 10.2K | $5.95M | — | Held |
| Icahn Capital | 10K | $5.83M | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 9.28K | $5.4M | — | Held |
| Verition Fund Management LLC | 8.89K | $5.18M | — | Held |
| Engineers Gate Manager LP | 8.71K | $5.07M | — | Held |
| Hennion & Walsh Asset Management, Inc. | 8.16K | $4.75M | — | Held |
| Trexquant Investment LP | 7.78K | $4.53M | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 7.3K | $4.25M | — | Held |
| PRINCIPAL FINANCIAL GROUP INC | 7.26K | $4.23M | — | Held |
| PFM Health Sciences, LP | 7.26K | $4.23M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 6.98K | $4.06M | — | Held |
| Entropy Technologies, LP | 6.94K | $4.04M | — | Held |
| Capricorn Fund Managers Ltd | 6.6K | $3.84M | — | Held |
| Calamos Advisors LLC | 6.57K | $3.82M | — | Held |
| Susquehanna Portfolio Strategies, LLC | 6.25K | $3.64M | — | Held |
| VICTORY CAPITAL MANAGEMENT INC | 5.82K | $3.39M | — | Held |
| F/m Investments LLC | 5.74K | $3.34M | — | Held |
| PRUDENTIAL FINANCIAL INC | 5.67K | $3.3M | — | Held |
| Assenagon Asset Management S.A. | 5.39K | $3.14M | — | Held |
| Orion Porfolio Solutions, LLC | 5.35K | $3.12M | — | Held |
| TUDOR INVESTMENT CORP ET AL | 5.29K | $3.08M | $114.5K | Added$2.65M |
| Fieldview Capital Management, LLC | 5.2K | $3.03M | — | Held |
| O'Neil Global Advisors, Inc. | 5.06K | $2.95M | — | Held |
| State of New Jersey Common Pension Fund D | 5.04K | $2.94M | — | Held |
| Police & Firemen's Retirement System of New Jersey | 5.02K | $2.92M | — | Held |
| ASSETMARK, INC | 4.81K | $2.8M | — | Held |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 4.76K | $2.77M | — | Held |
| Pathstone Holdings, LLC | 4.73K | $2.76M | — | Held |
| PEAK FINANCIAL ADVISORS LLC | 4.47K | $2.6M | — | Held |
| ProShare Advisors LLC | 4.45K | $2.59M | — | Held |
| PROFUND ADVISORS LLC | 4.16K | $2.42M | — | Held |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 5.6K | $2.4M | — | Held |
| ARIZONA STATE RETIREMENT SYSTEM | 4.04K | $2.35M | — | Held |
| Cetera Investment Advisers | 3.94K | $2.3M | — | Held |
| Moody Aldrich Partners LLC | 3.88K | $2.26M | — | Held |
| Knights of Columbus Asset Advisors LLC | 3.7K | $2.16M | — | Held |
| China Universal Asset Management Co., Ltd. | 3.7K | $2.16M | — | Held |
| Cinctive Capital Management LP | 3.69K | $2.15M | — | Held |
| Brevan Howard Capital Management LP | 3.63K | $2.12M | — | Held |
| Allworth Financial LP | 3.56K | $2.07M | $438.8K | Added$444.6K |
| Newbridge Financial Services Group, Inc. | 3.55K | $2.07M | — | Held |
| MARTINGALE ASSET MANAGEMENT L P | 3.39K | $1.97M | — | Held |
| FARALLON CAPITAL MANAGEMENT LLC | 3.32K | $1.93M | $410.5K | Added$410.5K |
| SPHERA FUNDS MANAGEMENT LTD. | 3.3K | $1.92M | — | Held |
| STRS OHIO | 3.3K | $1.92M | — | Held |
| KLP KAPITALFORVALTNING AS | 3.24K | $1.89M | — | Held |
| OSAIC HOLDINGS, INC. | 3.05K | $1.78M | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 2.98K | $1.73M | — | Held |
| Penn Capital Management Company, LLC | 2.9K | $1.72M | — | Held |
| Bellevue Group AG | 2.88K | $1.68M | — | Held |
| Dana Investment Advisors, Inc. | 2.87K | $1.67M | — | Held |
| HighVista Strategies LLC | 2.84K | $1.65M | — | Held |
| XTX Topco Ltd | 2.82K | $1.64M | — | Held |
| AMI ASSET MANAGEMENT CORP | 2.75K | $1.6M | — | Held |
| Aigen Investment Management, LP | 2.65K | $1.54M | — | Held |
| QUADRANT CAPITAL GROUP LLC | 2.6K | $1.52M | — | Held |
| BAMCO INC /NY/ | 2.5K | $1.46M | — | Held |
| Strid Group, LLC | 2.5K | $1.46M | — | Held |
| Mariner, LLC | 2.43K | $1.41M | — | Held |
| Allianz Asset Management GmbH | 2.4K | $1.4M | — | Held |
| COMMONWEALTH EQUITY SERVICES, LLC | 2.34K | $1.36M | — | Held |
| STIFEL FINANCIAL CORP | 2.33K | $1.36M | — | Held |
| Jefferies Financial Group Inc. | 2.3K | $1.34M | — | Held |
| Inspire Investing, LLC | 2.26K | $1.31M | — | Held |
| Snowden Capital Advisors LLC | 2.23K | $1.3M | — | Held |
| GUGGENHEIM CAPITAL LLC | 2.16K | $1.26M | — | Held |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 2.15K | $1.25M | — | Held |
| D.A. DAVIDSON & CO. | 2.13K | $1.24M | — | Held |
| Knott David M Jr | 2K | $1.16M | — | Held |
| TOTH FINANCIAL ADVISORY CORP | 2K | $1.16M | — | Held |
| FORA Capital, LLC | 2K | $1.16M | — | Held |
| Illinois Municipal Retirement Fund | 1.9K | $1.11M | — | Held |
| Seven Fleet Capital Management LP | 1.86K | $1.08M | — | Held |
| MML INVESTORS SERVICES, LLC | 1.67K | $971.3K | — | Held |
| Kestra Advisory Services, LLC | 1.58K | $920.1K | — | Held |
| TEMA ETFS LLC | 1.57K | $914.9K | — | Held |
| NEOS Investment Management LLC | 1.57K | $914.9K | — | Held |
| J. Safra Sarasin Holding AG | 1.55K | $900.3K | — | Held |
| Ameritas Investment Partners, Inc. | 1.54K | $894.5K | — | Held |
| AlTi Global, Inc. | 1.49K | $869.4K | — | Held |
| XPONANCE LLC | 1.46K | $852K | — | Held |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 1.51K | $844.3K | — | Held |
| Cerity Partners LLC | 1.44K | $840.9K | — | Held |
| NEW YORK LIFE INVESTMENT MANAGEMENT LLC | 1.39K | $807.1K | — | Held |
| Sanctuary Advisors, LLC | 1.37K | $798.4K | $169.6K | Added$126.5K |
| TWO SIGMA SECURITIES, LLC | 1.34K | $778K | — | Held |
| OPPENHEIMER ASSET MANAGEMENT INC. | 1.31K | $764.6K | — | Held |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 1.28K | $747.1K | — | Held |
| Vanguard Personalized Indexing Management, LLC | 1.25K | $727.3K | — | Held |
| Federation des caisses Desjardins du Quebec | 1.25K | $725.6K | — | Held |
| CIBC WORLD MARKETS CORP | 1.23K | $716.9K | — | Held |
| B. Metzler seel. Sohn & Co. AG | 1.22K | $711K | — | Held |
| Virtus Investment Advisers, LLC | 1.19K | $695.3K | — | Held |
| HighTower Advisors, LLC | 1.17K | $683.1K | — | Held |
| Everhart Financial Group, Inc. | 1.16K | $677.3K | — | Held |
| Verity Asset Management, Inc. | 1.16K | $674.4K | — | Held |
| CAPTRUST FINANCIAL ADVISORS | 1.13K | $658.6K | — | Held |
| HSBC HOLDINGS PLC | 1.1K | $646.2K | — | Held |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 1.09K | $633.6K | — | Held |
| PIER 88 INVESTMENT PARTNERS LLC | 1.08K | $628.9K | — | Held |
| Graham Capital Management, L.P. | 1.06K | $618.4K | — | Held |
| NATIXIS | 1.04K | $606.2K | — | Held |
| Cynosure Group, LLC | 1.02K | $596.9K | — | Held |
| BLAIR WILLIAM & CO/IL | 1K | $582.3K | — | Held |
| Optimize Financial Inc | 992 | $577.7K | — | Held |
| Atria Investments, Inc | 988 | $575.4K | — | Held |
| SYON CAPITAL LLC | 965 | $562K | — | Held |
| Baader Bank Aktiengesellschaft | 902 | $524.8K | — | Held |
| ADAR1 Capital Management, LLC | 895 | $521.2K | — | Held |
| PSP Research LLC | 892 | $519.4K | — | Held |
| INTRUST BANK NA | 848 | $493.8K | — | Held |
| IFG Advisory, LLC | 844 | $491.5K | — | Held |
| QRG CAPITAL MANAGEMENT, INC. | 834 | $485.7K | — | Held |
| ELEVATION POINT WEALTH PARTNERS, LLC | 824 | $479.8K | $87K | Added$385.7K |
| CIBC Asset Management Inc | 816 | $475.2K | — | Held |
| PharVision Advisers, LLC | 813 | $473.4K | — | Held |
| Vestmark Advisory Solutions, Inc. | 806 | $469.4K | — | Held |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 800 | $465.9K | — | Held |
| Chicago Partners Investment Group LLC | 961 | $461.7K | — | Held |
| Vise Technologies, Inc. | 769 | $447.8K | — | Held |
| Dorsey & Whitney Trust CO LLC | 752 | $437.9K | — | Held |
| COMERICA BANK | 743 | $433.1K | — | Held |
| Eurizon Capital SGR S.p.A. | 729 | $424.8K | — | Held |
| Abel Hall, LLC | 710 | $413.5K | — | Held |
| Composition Wealth, LLC | 703 | $409.4K | — | Held |
| Cannon Global Investment Management, LLC | 700 | $407.6K | — | Held |
| GLENMEDE TRUST CO NA | 691 | $402.4K | — | Held |
| Swiss Life Asset Management Ltd | 690 | $401.8K | $79.9K | Added$105.5K |
| Advisory Services Network, LLC | 658 | $383.2K | — | Held |
| Allspring Global Investments Holdings, LLC | 631 | $374.7K | — | Held |
| M&T Bank Corp | 629 | $365.9K | — | Held |
| CARY STREET PARTNERS FINANCIAL LLC | 628 | $365.7K | — | Held |
| JGP Global Gestao de Recursos Ltda. | 625 | $364K | — | Held |
| Tower Research Capital LLC (TRC) | 612 | $356.4K | — | Held |