13F

Stock

Lyell Immunopharma, Inc.

LYEL · held by 74 managers

Reported value

$250.8M

Holders

74

+14 new · −9 exited

Holders’ est. mark

−$109.2M

Price effect on 56 books still in the name

Largest holder

$65.1M

ARCH Venture Management, LLC

Notable conviction

Share of each notable manager’s 13F book.

Holder count by quarter

Who holds it

Notable only
InvestorSharesValueEst. markChange
ARCH Venture Management, LLC3.25M$65.1M−$29.6MCut−$19.8M
GSK plc1.51M$30.3M−$16.2MCut−$16.2M
Foresite Capital Management IV, LLC800.4K$16.1M−$8.58MCut−$8.58M
Orland Properties Ltd754.7K$15.1M−$8.09MCut−$8.09M
VANGUARD CAPITAL MANAGEMENT LLC718.2K$14.4MHeld
Decheng Capital LLC692K$13.9M−$7.42MCut−$7.42M
Almitas Capital LLC577.8K$11.6M−$6.19MCut−$6.19M
Foresite Capital Management V, LLC477.1K$9.57M−$5.11MCut−$5.11M
MILLENNIUM MANAGEMENT LLC458.9K$9.21M−$628.7KAdded$7.4M
Citadel381.5K$7.65M−$3.48MCut−$2.34M
venBio Partners LLC337.7K$6.77M−$3.62MCut−$3.62M
SUSQUEHANNA INTERNATIONAL GROUP, LLP310.2K$6.22M−$1.62MAdded$1.57M
Alphabet Inc.293.3K$5.88M−$3.14MCut−$3.14M
BlackRock, Inc.191.8K$3.85M−$1.95MCut−$1.75M
GEODE CAPITAL MANAGEMENT, LLC167K$3.35M−$1.75MCut−$1.67M
MARSHALL WACE, LLP148.5K$2.98M−$785.9KAdded$722.6K
Renaissance Technologies116.4K$2.34M−$423.3KAdded$1.12M
GOLDMAN SACHS GROUP INC114.5K$2.3M−$1.04MCut−$679K
Velan Capital Investment Management LP102K$2.05MNew
MIC Capital Management UK LLP87K$1.75M−$932.9KCut−$932.9K
VANGUARD FIDUCIARY TRUST CO86.9K$1.74MHeld
CHARLES SCHWAB INVESTMENT MANAGEMENT INC86K$1.72M−$915.7KCut−$904.7K
Opaleye Management Inc.79.1K$1.59MNew
State Street72.5K$1.45M−$551.8KCut−$129.5K
JANE STREET GROUP, LLC63.9K$1.28M−$133KAdded$899.7K
MORGAN STANLEY56.2K$1.13M−$460.4KCut−$195.6K
Qube Research & Technologies Ltd55.1K$1.11M−$97KAdded$826.9K
DIMENSIONAL FUND ADVISORS LP47.9K$959KNew
RBF Capital, LLC44.1K$884.5K−$472.7KCut−$1.41M
Ikarian Capital, LLC41.1K$824.1K−$440.4KCut−$440.4K
Clearstead Advisors, LLC39.9K$800.7KNew
BANK OF AMERICA CORP /DE/33.3K$668.4K−$86.2KAdded$420.8K
UBS Group AG31.8K$638.2K−$141.5KAdded$231.8K
NORTHERN TRUST CORP30.3K$607.4K−$324.6KCut−$324.6K
CANADA PENSION PLAN INVESTMENT BOARD29.4K$590K−$315.3KCut−$398.4K
VANGUARD PORTFOLIO MANAGEMENT LLC23K$461.7KHeld
Walleye Capital LLC22.2K$445.5KNew
Point72 Asset Management, L.P.21.3K$427.1K−$123.1KAdded$73.8K
Susquehanna Portfolio Strategies, LLC20.8K$417.2K−$223KCut−$223K
Jump Financial, LLC20.1K$403.7KNew
Squarepoint Ops LLC19.3K$387KNew
BRIDGEWAY CAPITAL MANAGEMENT, LLC18K$361.1K−$193KCut−$193K
AMERICAN CENTURY COMPANIES INC16K$320.4KNew
Brevan Howard Capital Management LP13.4K$269.5KNew
TWO SIGMA INVESTMENTS, LP11.6K$232.4K−$124.2KCut−$248.3K
CITIGROUP INC5.91K$118.6K−$45.4KCut−$11.7K
Vanguard Global Advisers, LLC5.17K$103.6KHeld
China Universal Asset Management Co., Ltd.3.77K$75.6K−$37.1KCut−$30.8K
HSG Holding Ltd152.3K$73.1K−$3.86MCut−$3.86M
BNP PARIBAS FINANCIAL MARKETS2.1K$42.1K−$22.5KCut−$55.5K
Fidelity1.82K$36.6K−$19.5KCut−$19.7K
BARCLAYS PLC1.67K$33.5K−$17.9KCut−$457.9K
JPMORGAN CHASE & CO1.47K$28.3K−$16.9KCut−$21.4K
Tower Research Capital LLC (TRC)1.3K$26.1K−$12.8KCut−$10.7K
Mirae Asset Global Investments Co., Ltd.1.11K$22.2K−$11.1KCut−$9.51K
JONES FINANCIAL COMPANIES LLLP1.02K$20.2K−$11.4KCut−$11.4K
SIMPLEX TRADING, LLC693$13.9K−$396Added$12.8K
IFP Advisors, Inc648$13KNew
Advisors Asset Management, Inc.567$11.4K−$6.08KCut−$6.08K
GF FUND MANAGEMENT CO. LTD.470$9.43K−$4.46KCut−$3.38K
Zurcher Kantonalbank (Zurich Cantonalbank)447$8.97KNew
ROYAL BANK OF CANADA251$6K−$426Added$5K
Seneschal Advisors, LLC126$2.53KNew
WELLS FARGO & COMPANY/MN125$2.51K−$1.34KCut−$1.34K
OSAIC HOLDINGS, INC.124$2.49K−$1.33KCut−$1.33K
GROUP ONE TRADING LLC100$2.01KNew
MAI Capital Management100$2.01K−$1.07KCut−$1.07K
US BANCORP \DE\58$1.16K−$622Cut−$622
Cornerstone Financial Management LLC46$923−$493Cut−$493
Allworth Financial LP43$863New
GAMMA Investing LLC35$702−$375Cut−$375
NISA INVESTMENT ADVISORS, LLC25$502−$268Cut−$268
PRICE T ROWE ASSOCIATES INC /MD/13.1K$264−$141Cut−$141
CWM, LLC2$40$40Added$39

Who left

Positions as of Q1 2026. 13F filings arrive up to 45 days after quarter-end and omit shorts. Values are quarter-end marks, as filed. Estimated mark is the price effect on shares still held — not realized P&L or investment advice.