| Bain Capital Life Sciences Investors, LLC | 12.4M | $362.9M | — | Held |
| HealthCor Partners Management LP | 6.7M | $195.2M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 5.89M | $171.8M | — | Held |
| Fidelity | 4.12M | $120.2M | — | Held |
| BAILLIE GIFFORD & CO | 3.01M | $87.6M | — | Held |
| BAMCO INC /NY/ | 2.3M | $67.2M | — | Held |
| Schusterman Interests, LLC | 1.94M | $56.5M | — | Held |
| Capricorn Investment Group LLC | 1.66M | $48.2M | — | Held |
| Vanguard | 1.58M | $46.1M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1.43M | $41.7M | — | Held |
| BlackRock, Inc. | 1.34M | $39.1M | — | Held |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 1.26M | $36.7M | — | Held |
| Citadel | 1.25M | $36.4M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 1.09M | $31.7M | — | Held |
| JANUS HENDERSON GROUP PLC | 865.6K | $25.2M | — | Held |
| MORGAN STANLEY | 745.9K | $21.7M | −$3.36M | Cut−$3.67M |
| Ensign Peak Advisors, Inc | 700.8K | $20.4M | — | Held |
| FRANKLIN RESOURCES INC | 685.2K | $20M | — | Held |
| JPMORGAN CHASE & CO | 586.3K | $17.1M | — | Held |
| Invesco Ltd. | 577.4K | $16.8M | — | Held |
| EVENTIDE ASSET MANAGEMENT, LLC | 506K | $14.7M | — | Held |
| UBS Group AG | 501.2K | $14.6M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 499.9K | $14.6M | — | Held |
| RTW INVESTMENTS, LP | 495K | $14.4M | — | Held |
| FRED ALGER MANAGEMENT, LLC | 440.5K | $12.8M | — | Held |
| State Street | 322.4K | $9.4M | — | Held |
| Board of Trustees of The Leland Stanford Junior University | 312.2K | $9.1M | — | Held |
| Point72 Asset Management, L.P. | 304.5K | $8.88M | — | Held |
| Rock Springs Capital Management LP | 277.7K | $8.09M | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 228.6K | $6.66M | — | Held |
| Alyeska Investment Group, L.P. | 225K | $6.56M | — | Held |
| EMERALD ADVISERS, LLC | 221.6K | $6.46M | — | Held |
| NZS Capital, LLC | 209.7K | $6.11M | — | Held |
| GILDER GAGNON HOWE & CO LLC | 185.9K | $5.42M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 153.3K | $4.47M | — | Held |
| Freestone Grove Partners LP | 150K | $4.37M | — | Held |
| GOLDMAN SACHS GROUP INC | 147.2K | $4.29M | — | Held |
| NORTHERN TRUST CORP | 138.8K | $4.04M | — | Held |
| EMERALD MUTUAL FUND ADVISERS TRUST | 131.3K | $3.83M | — | Held |
| Catalio Capital Management, LP | 113.9K | $3.32M | — | Held |
| ROYAL BANK OF CANADA | 110.5K | $3.22M | — | Held |
| AMERIPRISE FINANCIAL INC | 101.5K | $2.96M | — | Held |
| SEVEN GRAND MANAGERS, LLC | 100K | $2.92M | — | Held |
| West Family Investments, Inc. | 87.8K | $2.56M | −$395.9K | Cut−$395.9K |
| BANK OF AMERICA CORP /DE/ | 86.7K | $2.53M | −$293.1K | Added$341.2K |
| Ghisallo Capital Management LLC | 75K | $2.19M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 67.8K | $1.98M | — | Held |
| BURKEHILL GLOBAL MANAGEMENT, LP | 65K | $1.89M | — | Held |
| VARCOV Co. | 56.8K | $1.66M | — | Held |
| TD Asset Management Inc | 56.6K | $1.65M | — | Held |
| Brevan Howard Capital Management LP | 52.6K | $1.53M | — | Held |
| Bank of New York Mellon Corp | 48.7K | $1.42M | — | Held |
| Lisanti Capital Growth, LLC | 43.8K | $1.28M | — | Held |
| XTX Topco Ltd | 43.2K | $1.26M | — | Held |
| XXEC, Inc. | 41.9K | $1.22M | — | Held |
| Swiss National Bank | 41.1K | $1.2M | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 36.9K | $1.11M | — | Held |
| NORGES BANK | 35K | $1.02M | — | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 32.8K | $955.3K | — | Held |
| BCWM, LLC | 31.1K | $907.7K | — | Held |
| BARCLAYS PLC | 30.3K | $884.3K | −$75.4K | Added$321.6K |
| TrueMark Investments, LLC | 26.5K | $772.6K | — | Held |
| Nuveen, LLC | 23.2K | $677.4K | — | Held |
| WELLS FARGO & COMPANY/MN | 21.5K | $626.4K | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 20.7K | $603.2K | — | Held |
| RHUMBLINE ADVISERS | 20.1K | $584.6K | — | Held |
| Lykos Global Management, LP | 20K | $583K | — | Held |
| Quent Capital, LLC | 20K | $583K | — | Held |
| D. E. Shaw & Co., Inc. | 18.5K | $539.7K | — | Held |
| Legal & General Group Plc | 17.7K | $516.5K | — | Held |
| BRANDYWINE MANAGERS, LLC | 16.8K | $489K | — | Held |
| Legato Capital Management LLC | 16.2K | $471.6K | — | Held |
| Sandia Investment Management LP | 15.9K | $464K | — | Held |
| Perpetual Ltd | 15.7K | $458.9K | — | Held |
| SEI INVESTMENTS CO | 15.2K | $441.7K | — | Held |
| DEUTSCHE BANK AG\ | 13.8K | $403.6K | — | Held |
| BOOTHBAY FUND MANAGEMENT, LLC | 11.3K | $329.7K | — | Held |
| MetLife Investment Management, LLC | 11K | $321.7K | — | Held |
| STIFEL FINANCIAL CORP | 10.6K | $308.3K | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 8.6K | $250.7K | — | Held |
| CONNABLE OFFICE INC | 7.55K | $220.1K | — | Held |
| STALEY CAPITAL ADVISERS INC | 7K | $204.1K | — | Held |
| KLP KAPITALFORVALTNING AS | 4.5K | $131.2K | — | Held |
| Police & Firemen's Retirement System of New Jersey | 4.49K | $130.9K | — | Held |
| STRS OHIO | 3.4K | $99.1K | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 3.1K | $90.4K | — | Held |
| Caitong International Asset Management Co., Ltd | 2.48K | $72.3K | — | Held |
| CITIGROUP INC | 2.44K | $71.3K | — | Held |
| Ameritas Investment Partners, Inc. | 1.58K | $45.9K | — | Held |
| Russell Investments Group, Ltd. | 1.54K | $44.8K | — | Held |
| PRICE T ROWE ASSOCIATES INC /MD/ | 863.3K | $25.2K | — | Held |
| LORD, ABBETT & CO. LLC | 790.9K | $23.1K | — | Held |
| JONES FINANCIAL COMPANIES LLLP | 600 | $17.5K | — | Held |
| Sterling Capital Management LLC | 597 | $17.4K | — | Held |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 490 | $14.3K | — | Held |
| Tower Research Capital LLC (TRC) | 459 | $13.4K | — | Held |
| COMERICA BANK | 351 | $10.2K | — | Held |
| MAI Capital Management | 334 | $9.74K | — | Held |
| Center for Financial Planning, Inc. | 268 | $7.81K | — | Held |
| Quarry LP | 90 | $2.62K | — | Held |
| Bell Investment Advisors, Inc | 70 | $2.04K | — | Held |
| Rachor Investment Advisory Services, LLC | 65 | $1.9K | — | Held |
| Steward Partners Investment Advisory, LLC | 62 | $1.81K | — | Held |
| Nemes Rush Group LLC | 27 | $787 | — | Held |
| OSAIC HOLDINGS, INC. | 25 | $728 | — | Held |
| Bare Financial Services, Inc | 16 | $466 | — | Held |
| SG Americas Securities, LLC | 10.7K | $312 | — | Held |
| Thrivent Financial for Lutherans | 8.61K | $251 | — | Held |
| Rockefeller Capital Management L.P. | 6 | $175 | — | Held |
| AMALGAMATED BANK | 610 | $18 | — | Held |
| FNY Investment Advisers, LLC | 290 | $8 | — | New |
| CWM, LLC | 44 | $1 | — | Held |
| Avion Wealth | 17 | $0 | — | Held |