| ORBIMED ADVISORS LLC | 1.25M | $11.3M | −$4.13M | Cut−$4.13M |
| JANUS HENDERSON GROUP PLC | 1.23M | $11.1M | −$3.76M | Cut−$2.98M |
| Parkman Healthcare Partners LLC | 521.1K | $4.72M | — | New |
| BlackRock, Inc. | 446.9K | $4.04M | −$1.41M | Cut−$1.23M |
| Schonfeld Strategic Advisors LLC | 283.2K | $2.56M | — | New |
| VANGUARD CAPITAL MANAGEMENT LLC | 276.1K | $2.5M | — | Held |
| KCM Capital Inc | 200K | $1.81M | — | New |
| GEODE CAPITAL MANAGEMENT, LLC | 193.2K | $1.75M | −$535K | Cut−$253.1K |
| Russell Investments Group, Ltd. | 159.3K | $1.44M | −$525.7K | Cut−$537.4K |
| State Street | 113.7K | $1.03M | −$227.5K | Added$177.7K |
| NORTHERN TRUST CORP | 54.5K | $493K | −$167.3K | Cut−$133.1K |
| KORNITZER CAPITAL MANAGEMENT INC /KS | 53.4K | $483.6K | −$176.3K | Cut−$198.6K |
| BURKEHILL GLOBAL MANAGEMENT, LP | 50K | $452.5K | −$165K | Cut−$165K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 47.6K | $431.2K | — | Held |
| VANGUARD FIDUCIARY TRUST CO | 45.4K | $410.9K | — | Held |
| Citadel | 44.6K | $403.6K | — | New |
| WESBANCO BANK INC | 37K | $334.9K | −$122.1K | Cut−$122.1K |
| Boston Partners | 25.2K | $228.1K | −$83.2K | Cut−$94.3K |
| XTX Topco Ltd | 24.7K | $223.9K | — | New |
| GOLDMAN SACHS GROUP INC | 22.6K | $204.9K | −$44.9K | Added$36.9K |
| TD Waterhouse Canada Inc. | 20K | $192K | −$53.6K | Cut−$1.96M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 16.8K | $151.8K | −$55.4K | Cut−$55.4K |
| BANK OF AMERICA CORP /DE/ | 15.6K | $141K | −$51.4K | Cut−$120K |
| MERCER GLOBAL ADVISORS INC /ADV | 15.1K | $136.6K | −$49.8K | Cut−$50.6K |
| JANE STREET GROUP, LLC | 15K | $136.1K | — | New |
| Quadrature Capital Ltd | 13.4K | $120.8K | — | New |
| Bank of New York Mellon Corp | 13.1K | $118.6K | −$43.2K | Cut−$43.2K |
| Centiva Capital, LP | 12.7K | $115.3K | — | New |
| Board of Trustees of The Leland Stanford Junior University | 12.5K | $113.3K | −$41.3K | Cut−$195.8K |
| MORGAN STANLEY | 11.4K | $103.4K | −$37.7K | Cut−$61.2K |
| Renaissance Technologies | 10.4K | $94.1K | −$34.3K | Cut−$206K |
| UBS Group AG | 10.3K | $93.2K | −$34K | Cut−$38.7K |
| DEUTSCHE BANK AG\ | 9.83K | $89K | −$32.4K | Cut−$32.4K |
| RHUMBLINE ADVISERS | 5.18K | $46.9K | −$14.6K | Cut−$7.69K |
| JPMORGAN CHASE & CO | 5.06K | $46.7K | −$10.1K | Added$6.59K |
| Vanguard Global Advisers, LLC | 3.58K | $32.4K | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 3.35K | $30.3K | −$10.7K | Cut−$9.71K |
| WELLS FARGO & COMPANY/MN | 3.33K | $30.2K | −$11K | Cut−$66.6K |
| BNP PARIBAS FINANCIAL MARKETS | 2.57K | $23.2K | −$7.09K | Cut−$3.32K |
| NEW YORK STATE COMMON RETIREMENT FUND | 1.8K | $16.3K | −$5.94K | Cut−$5.94K |
| BARCLAYS PLC | 1.78K | $16.1K | −$5.86K | Cut−$115.2K |
| Tower Research Capital LLC (TRC) | 1.67K | $15.1K | −$3.41K | Added$2.36K |
| Fidelity | 1.3K | $11.7K | −$1.01K | Added$7.94K |
| Police & Firemen's Retirement System of New Jersey | 1.26K | $11.4K | −$4.15K | Cut−$4.15K |
| US BANCORP \DE\ | 600 | $5.43K | — | New |
| Legal & General Group Plc | 579 | $5.26K | −$1.87K | Cut−$2.83K |
| Ameritas Investment Partners, Inc. | 565 | $5.11K | −$1.86K | Cut−$1.86K |
| ROYAL BANK OF CANADA | 572 | $5K | −$2.25K | Cut−$8K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 460 | $4.16K | −$1.38K | Cut−$987 |
| CITIGROUP INC | 409 | $3.7K | −$617 | Added$1.39K |
| JONES FINANCIAL COMPANIES LLLP | 380 | $3.67K | −$1.02K | Cut−$1.02K |
| GAMMA Investing LLC | 135 | $1.22K | — | New |
| Sterling Capital Management LLC | 130 | $1.18K | −$429 | Cut−$1.03K |
| CWM, LLC | 59 | $534 | $533 | Added$532 |
| Sunrise Financial Services, LLC | 26 | $235 | — | New |
| OSAIC HOLDINGS, INC. | 20 | $181 | −$66 | Cut−$66 |
| Root Financial Partners, LLC | 15 | $136 | — | New |
| HRT FINANCIAL LP | 12.3K | $111 | — | New |
| MAI Capital Management | 4 | $37 | — | New |
| Caitong International Asset Management Co., Ltd | 4 | $36 | — | New |
| Essential Partners LLC | 4 | $36 | −$3 | Added$24 |
| Advisory Services Network, LLC | 3 | $27 | — | New |
| Allworth Financial LP | 2 | $19 | −$6 | Cut−$6 |
| Farther Finance Advisors, LLC | 2 | $19 | — | New |
| True Wealth Design, LLC | 2 | $19 | −$6 | Cut−$31 |
| IFP Advisors, Inc | 1 | $9 | −$4 | Cut−$16 |