| BVF INC/IL | 19.8M | $62.2M | — | Held |
| WELLS FARGO & COMPANY/MN | 1.01M | $3.16M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 933.3K | $2.93M | — | Held |
| Renaissance Technologies | 668.9K | $2.1M | — | Held |
| BlackRock, Inc. | 502.2K | $1.58M | — | Held |
| Point72 Asset Management, L.P. | 384.8K | $1.21M | — | Held |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 375.6K | $1.18M | — | Held |
| NORTHERN TRUST CORP | 282K | $885.3K | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 213.5K | $670.4K | — | Held |
| UBS Group AG | 194.3K | $610.3K | — | Held |
| MARSHALL WACE, LLP | 186.7K | $586.3K | — | Held |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 147.6K | $463.5K | — | Held |
| Dauntless Investment Group, LLC | 115.7K | $363.2K | — | Held |
| MORGAN STANLEY | 94.3K | $296.2K | $23K | Added$30.3K |
| TWO SIGMA INVESTMENTS, LP | 87.9K | $276K | — | Held |
| Citadel | 71.2K | $223.4K | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 63.6K | $199.7K | — | Held |
| BANK OF AMERICA CORP /DE/ | 21.5K | $67.4K | $1.48K | Added$50.3K |
| GOLDMAN SACHS GROUP INC | 18.6K | $58.3K | — | Held |
| China Universal Asset Management Co., Ltd. | 16.4K | $51.4K | — | Held |
| SEI INVESTMENTS CO | 15.9K | $49.9K | — | Held |
| EFG International AG | 12.9K | $40.5K | — | Held |
| JANE STREET GROUP, LLC | 10.7K | $33.6K | — | Held |
| Quinn Opportunity Partners LLC | 10.1K | $31.7K | — | Held |
| Silverberg Bernstein Capital Management LLC | 10K | $31.3K | — | Held |
| JPMORGAN CHASE & CO | 8.72K | $27.4K | — | Held |
| Banque Cantonale Vaudoise | 7.89K | $25K | — | Held |
| Tower Research Capital LLC (TRC) | 6.17K | $19.4K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 4.88K | $15.3K | — | Held |
| Leonteq Securities AG | 3K | $9.42K | — | New |
| CITIGROUP INC | 2.8K | $8.79K | — | Held |
| BARCLAYS PLC | 2.7K | $8.48K | $675 | Cut−$6.81K |
| BNP PARIBAS FINANCIAL MARKETS | 2.48K | $7.79K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 1.97K | $6.19K | — | Held |
| Rockefeller Capital Management L.P. | 1K | $3.14K | — | Held |
| Activest Wealth Management | 1K | $3.14K | — | Held |
| ROYAL BANK OF CANADA | 858 | $2K | — | Held |
| SBI Securities Co., Ltd. | 547 | $1.72K | — | Held |
| ACADIAN ASSET MANAGEMENT LLC | 464.7K | $1.44K | — | Held |
| OSAIC HOLDINGS, INC. | 221 | $693 | — | Held |
| Strengthening Families & Communities, LLC | 200 | $628 | — | Held |