| BAKER BROS. ADVISORS LP | 42.9M | $1.15B | — | Held |
| BlackRock, Inc. | 20.8M | $554.4M | — | Held |
| Vanguard | 15.2M | $404.8M | — | Held |
| State Street | 7.91M | $211.3M | — | Held |
| RTW INVESTMENTS, LP | 7.14M | $190.8M | — | Held |
| Point72 Asset Management, L.P. | 3.38M | $90.2M | — | Held |
| GEODE CAPITAL MANAGEMENT, LLC | 3.24M | $86.5M | — | Held |
| DIMENSIONAL FUND ADVISORS LP | 2.92M | $78M | — | Held |
| Palo Alto Investors LP | 2.48M | $66.3M | — | Held |
| FIRST TRUST ADVISORS LP | 2.27M | $60.6M | — | Held |
| BRAIDWELL LP | 2.03M | $54.3M | — | Held |
| GOLDMAN SACHS GROUP INC | 1.57M | $41.9M | — | Held |
| FRED ALGER MANAGEMENT, LLC | 1.56M | $41.7M | — | Held |
| Pictet Asset Management Holding SA | 1.55M | $41.5M | — | Held |
| Renaissance Technologies | 1.53M | $40.9M | — | Held |
| NORGES BANK | 1.51M | $40.3M | $14.3M | Added$16.7M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1.5M | $40.1M | — | Held |
| Trails Edge Capital Partners, LP | 1.42M | $37.9M | — | Held |
| Citadel | 1.37M | $36.5M | — | Held |
| Frazier Life Sciences Management, L.P. | 1.3M | $34.6M | — | Held |
| NORTHERN TRUST CORP | 1.24M | $33M | — | Held |
| BANK OF AMERICA CORP /DE/ | 1.22M | $32.6M | $4.77M | Added$13.7M |
| Qube Research & Technologies Ltd | 1.2M | $32.1M | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.17M | $31.3M | — | Held |
| MORGAN STANLEY | 1.14M | $30.5M | $6.13M | Added$5.14M |
| TWO SIGMA INVESTMENTS, LP | 1.12M | $29.9M | — | Held |
| Rockefeller Capital Management L.P. | 1.11M | $29.7M | — | Held |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 1.07M | $28.6M | — | Held |
| Nuveen, LLC | 1.06M | $28.2M | — | Held |
| D. E. Shaw & Co., Inc. | 1.03M | $27.4M | — | Held |
| Logos Global Management LP | 850K | $22.7M | — | Held |
| Invesco Ltd. | 848K | $22.6M | — | Held |
| DEUTSCHE BANK AG\ | 828.6K | $22.1M | — | Held |
| EMERALD ADVISERS, LLC | 811.2K | $21.7M | — | Held |
| UBS Group AG | 769.4K | $20.6M | — | Held |
| Bank of New York Mellon Corp | 752K | $20.1M | — | Held |
| PRINCIPAL FINANCIAL GROUP INC | 745.4K | $19.9M | — | Held |
| Fidelity | 727K | $19.4M | — | Held |
| PANAGORA ASSET MANAGEMENT INC | 681.1K | $18.2M | — | Held |
| Fisher Asset Management, LLC | 665.1K | $17.8M | — | Held |
| AMERIPRISE FINANCIAL INC | 662.2K | $17.7M | — | Held |
| Allspring Global Investments Holdings, LLC | 658.8K | $17.3M | — | Held |
| VOYA INVESTMENT MANAGEMENT LLC | 641.5K | $17.1M | — | Held |
| JUPITER ASSET MANAGEMENT LTD | 621K | $16.6M | — | Held |
| Icahn Capital | 604.7K | $16.2M | — | Held |
| RICE HALL JAMES & ASSOCIATES, LLC | 603.7K | $16.1M | — | Held |
| Connor, Clark & Lunn Investment Management Ltd. | 581K | $15.5M | — | Held |
| MILLENNIUM MANAGEMENT LLC | 553.7K | $14.8M | — | Held |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 532.5K | $14.2M | — | Held |
| MARSHALL WACE, LLP | 493.4K | $13.2M | — | Held |
| PRUDENTIAL FINANCIAL INC | 485.9K | $13M | — | Held |
| EMERALD MUTUAL FUND ADVISERS TRUST | 484.5K | $12.9M | — | Held |
| GLENMEDE TRUST CO NA | 453.6K | $12.1M | — | Held |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 433.2K | $11.6M | — | Held |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 371K | $9.91M | — | Held |
| TWO SIGMA ADVISERS, LP | 370.2K | $9.89M | — | Held |
| BARCLAYS PLC | 368.3K | $9.84M | $1.98M | Added$554.8K |
| RHUMBLINE ADVISERS | 361.1K | $9.64M | — | Held |
| Man Group plc | 348.2K | $9.3M | — | Held |
| Edgestream Partners, L.P. | 316.2K | $8.45M | — | Held |
| Legal & General Group Plc | 314.4K | $8.4M | — | Held |
| GREAT LAKES ADVISORS, LLC | 313.5K | $8.37M | — | Held |
| TANG CAPITAL MANAGEMENT LLC | 300K | $8.01M | — | Held |
| Trexquant Investment LP | 297.8K | $7.95M | — | Held |
| Allianz Asset Management GmbH | 295.5K | $7.89M | — | Held |
| ROYAL BANK OF CANADA | 290.9K | $7.77M | — | Held |
| JANUS HENDERSON GROUP PLC | 290.1K | $7.75M | — | Held |
| JPMORGAN CHASE & CO | 270.8K | $7.23M | — | Held |
| NORDEA INVESTMENT MANAGEMENT AB | 237.6K | $6.35M | — | Held |
| Swiss National Bank | 232.9K | $6.22M | — | Held |
| LAZARD ASSET MANAGEMENT LLC | 226.2K | $6.04M | — | Held |
| F/m Investments LLC | 224K | $5.98M | — | Held |
| SPHERA FUNDS MANAGEMENT LTD. | 212.2K | $5.67M | — | Held |
| WELLS FARGO & COMPANY/MN | 209.2K | $5.59M | — | Held |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 205.4K | $5.49M | — | Held |
| Rafferty Asset Management, LLC | 198.3K | $5.3M | — | Held |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 194.1K | $5.19M | — | New |
| VICTORY CAPITAL MANAGEMENT INC | 177.6K | $4.74M | — | Held |
| Eversept Partners, LP | 176.6K | $4.72M | — | Held |
| FRANKLIN RESOURCES INC | 171.5K | $4.58M | — | Held |
| Birchview Capital, LP | 171K | $4.57M | — | Held |
| Ishara Investments LP | 160K | $4.27M | — | Held |
| ALPS ADVISORS INC | 158.2K | $4.23M | — | Held |
| ALLIANCEBERNSTEIN L.P. | 156.2K | $4.17M | — | Held |
| SEI INVESTMENTS CO | 154.1K | $4.12M | — | Held |
| ENVESTNET ASSET MANAGEMENT INC | 152.2K | $4.06M | — | Held |
| STATE OF WISCONSIN INVESTMENT BOARD | 150.4K | $4.02M | — | Held |
| HUSSMAN STRATEGIC ADVISORS, INC. | 147K | $3.93M | — | Held |
| Russell Investments Group, Ltd. | 138.3K | $3.69M | — | Held |
| Bridgewater | 138.2K | $3.69M | — | Held |
| Axecap Investments, LLC | 136.7K | $3.65M | — | Held |
| Erste Asset Management GmbH | 133.7K | $3.64M | — | Held |
| AMERICAN CENTURY COMPANIES INC | 129K | $3.45M | — | Held |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 128.7K | $3.44M | — | Held |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 126.8K | $3.39M | — | Held |
| SEGALL BRYANT & HAMILL, LLC | 126.1K | $3.37M | — | Held |
| MARTINGALE ASSET MANAGEMENT L P | 109.3K | $2.92M | — | Held |
| Jump Financial, LLC | 108.4K | $2.89M | — | Held |
| Avidity Partners Management LP | 106.9K | $2.86M | — | Held |
| BURNEY CO/ | 105.4K | $2.82M | — | Held |
| Phocas Financial Corp. | 104.1K | $2.78M | — | Held |
| Hennion & Walsh Asset Management, Inc. | 103.8K | $2.77M | — | Held |
| Nan Fung Group Holdings Ltd | 103K | $2.75M | — | Held |
| HOHIMER WEALTH MANAGEMENT, LLC | 101.8K | $2.72M | — | Held |
| Stonepine Capital Management, LLC | 100K | $2.67M | — | Held |
| GUGGENHEIM CAPITAL LLC | 94.7K | $2.53M | — | Held |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 92.6K | $2.48M | — | Held |
| CITIGROUP INC | 83.7K | $2.24M | — | Held |
| IEQ CAPITAL, LLC | 82.3K | $2.2M | — | Held |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 81.6K | $2.18M | — | Held |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 79.9K | $2.13M | — | Held |
| WESBANCO BANK INC | 78.2K | $2.09M | — | Held |
| PROFUND ADVISORS LLC | 77.1K | $2.06M | — | Held |
| ExodusPoint Capital Management, LP | 76.2K | $2.03M | — | Held |
| Engineers Gate Manager LP | 73.8K | $1.97M | — | Held |
| MetLife Investment Management, LLC | 70.5K | $1.88M | — | Held |
| Hudson Bay Capital Management LP | 70K | $1.87M | $375.9K | Added$369.5K |
| CANADA PENSION PLAN INVESTMENT BOARD | 68.1K | $1.82M | — | Held |
| Sofinnova Investments, Inc. | 65.6K | $1.75M | — | Held |
| Illinois Municipal Retirement Fund | 63.2K | $1.69M | — | Held |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 63K | $1.68M | — | Held |
| Weiss Asset Management LP | 58.7K | $1.57M | — | New |
| Louisiana State Employees Retirement System | 57.3K | $1.53M | — | Held |
| MACKENZIE FINANCIAL CORP | 57.3K | $1.53M | — | Held |
| Horizon Investments, LLC | 55.4K | $1.48M | — | Held |
| WELLINGTON MANAGEMENT GROUP LLP | 53.3K | $1.42M | — | Held |
| NEW YORK STATE COMMON RETIREMENT FUND | 52.1K | $1.39M | — | Held |
| INTECH INVESTMENT MANAGEMENT LLC | 48.3K | $1.29M | — | Held |
| State of Tennessee, Department of Treasury | 49.5K | $1.24M | — | Held |
| BNP PARIBAS FINANCIAL MARKETS | 44.8K | $1.2M | — | Held |
| KLP KAPITALFORVALTNING AS | 44.5K | $1.19M | — | Held |
| Creative Planning | 44K | $1.18M | — | Held |
| Concurrent Investment Advisors, LLC | 43.5K | $1.16M | — | Held |
| VIRTUS ADVISERS, LLC | 43K | $1.15M | $230.8K | Added$230.8K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 49.8K | $1.13M | — | Held |
| STRS OHIO | 41.4K | $1.11M | — | Held |
| Squarepoint Ops LLC | 40.7K | $1.09M | — | Held |
| State of New Jersey Common Pension Fund D | 40.3K | $1.08M | — | Held |
| LPL Financial LLC | 40.2K | $1.07M | — | Held |
| DIVERSIFIED TRUST CO | 39.8K | $1.06M | — | Held |
| Merit Financial Group, LLC | 39.4K | $1.05M | — | Held |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 37.8K | $1.01M | — | Held |
| Police & Firemen's Retirement System of New Jersey | 34.4K | $919K | — | Held |
| Brevan Howard Capital Management LP | 34.2K | $913.2K | — | Held |
| YOUSIF CAPITAL MANAGEMENT, LLC | 34.4K | $903.3K | — | Held |
| ARIZONA STATE RETIREMENT SYSTEM | 33K | $882.7K | — | Held |
| MML INVESTORS SERVICES, LLC | 32.7K | $874.4K | — | Held |
| COMERICA BANK | 31.8K | $850.4K | — | Held |
| ProShare Advisors LLC | 31.7K | $846.1K | — | Held |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 31K | $827.9K | — | Held |
| TRUIST FINANCIAL CORP | 29.8K | $796.9K | — | Held |
| AlphaQuest LLC | 28.8K | $769.1K | — | Held |
| OREGON PUBLIC EMPLOYEES RETIREMENT FUND | 28.7K | $765.7K | — | Held |
| CAPITAL FUND MANAGEMENT S.A. | 28.5K | $762.3K | — | Held |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 28.2K | $760.3K | — | Held |
| Cerity Partners LLC | 27.7K | $740.6K | — | Held |
| China Universal Asset Management Co., Ltd. | 27.6K | $736.3K | — | Held |
| BANK OF MONTREAL /CAN/ | 27.4K | $732.4K | — | Held |
| HSBC HOLDINGS PLC | 26.3K | $702.9K | — | Held |
| Virtus Investment Advisers, LLC | 25.2K | $672.3K | — | Held |
| Mariner, LLC | 24.2K | $645.2K | — | Held |
| CHOREO, LLC | 23.2K | $619.1K | — | Held |
| Atria Investments, Inc | 22K | $587.7K | — | Held |
| OP Asset Management Ltd | 21.7K | $579.6K | $34.5K | Added$442.6K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 20.7K | $551.6K | — | Held |
| RAYMOND JAMES FINANCIAL INC | 20.6K | $551.5K | — | Held |
| J.W. COLE ADVISORS, INC. | 20.6K | $551.1K | — | Held |
| PSP Research LLC | 19.8K | $528K | — | Held |
| AVIVA PLC | 19.3K | $515.8K | — | Held |
| Gotham Asset Management, LLC | 18.4K | $492.6K | — | Held |
| Maryland State Retirement & Pension System | 18.3K | $488.4K | — | Held |
| Amundi | 18.2K | $487.3K | — | Held |
| State of Wyoming | 17.8K | $475.8K | — | Held |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 17.4K | $466K | — | Held |
| Cetera Investment Advisers | 16.4K | $436.8K | — | Held |
| Quarry LP | 16K | $427.4K | — | Held |
| CoreCap Advisors, LLC | 15.4K | $410.4K | — | Held |
| COMMONWEALTH EQUITY SERVICES, LLC | 14.7K | $392.8K | — | Held |
| DNB Asset Management AS | 14.7K | $392.7K | — | Held |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 14.3K | $382.2K | — | Held |
| CIM INVESTMENT MANAGEMENT INC | 14.2K | $380.3K | — | Held |
| JGP Global Gestao de Recursos Ltda. | 13.8K | $369.7K | — | Held |
| Pallas Capital Advisors LLC | 13.2K | $352.4K | — | Held |
| STIFEL FINANCIAL CORP | 12.8K | $343K | — | Held |
| Entropy Technologies, LP | 12.8K | $341.8K | — | Held |
| denkapparat Operations GmbH | 12.5K | $334.9K | — | Held |
| Swiss Life Asset Management Ltd | 12.3K | $329.2K | — | New |
| Yorktown Management & Research Co Inc | 12.1K | $321.9K | — | Held |
| Advyzon Investment Management, LLC | 11.6K | $310.2K | — | Held |
| PERSONAL CFO SOLUTIONS, LLC | 11.3K | $302K | — | Held |
| Pinnacle Wealth Planning Services, Inc. | 11.2K | $299K | — | Held |
| Uniting Wealth Partners, LLC | 11K | $293.8K | — | Held |
| XPONANCE LLC | 11K | $293.6K | — | Held |
| Focus Partners Wealth | 10.7K | $284.6K | — | Held |
| Stirlingshire Investments, Inc. | 10.6K | $283.6K | — | Held |
| FOX RUN MANAGEMENT, L.L.C. | 10.6K | $281.8K | — | Held |
| Ameritas Investment Partners, Inc. | 10.4K | $277.7K | — | Held |
| EntryPoint Capital, LLC | 10.3K | $276.3K | — | Held |
| Quantinno Capital Management LP | 10.1K | $269.4K | — | Held |
| Abel Hall, LLC | 10.1K | $269.1K | — | Held |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 10K | $267.4K | — | Held |
| Kelsey Financial, LLC | 10K | $267.1K | — | Held |
| HighTower Advisors, LLC | 9.96K | $266.2K | — | Held |
| OSAIC HOLDINGS, INC. | 9.92K | $264.9K | — | Held |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 9.9K | $264.3K | — | Held |
| MERCER GLOBAL ADVISORS INC /ADV | 9.62K | $256.9K | — | Held |
| GARRISON POINT ADVISORS, LLC | 9.5K | $253.8K | — | Held |
| GROUP ONE TRADING LLC | 9.31K | $248.8K | — | Held |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 9.16K | $244.6K | — | Held |
| Violich Capital Management, Inc. | 9.03K | $241.1K | — | Held |
| Advisors Asset Management, Inc. | 8.77K | $234.2K | — | Held |
| Assenagon Asset Management S.A. | 8.72K | $232.8K | — | Held |
| Walleye Capital LLC | 8.48K | $226.4K | — | Held |
| Legato Capital Management LLC | 8.41K | $224.6K | — | Held |
| CAPTRUST FINANCIAL ADVISORS | 8.24K | $220.2K | — | Held |
| CIBC WORLD MARKETS CORP | 8.23K | $219.9K | — | Held |
| Mirae Asset Global Investments Co., Ltd. | 8.22K | $219.6K | — | Held |
| Ensign Peak Advisors, Inc | 7.9K | $211K | — | Held |
| Vanguard Personalized Indexing Management, LLC | 7.81K | $208.7K | — | Held |
| Westover Capital Advisors, LLC | 7.59K | $202.8K | — | Held |
| GLOBEFLEX CAPITAL L P | 7.54K | $201.3K | — | Held |
| Quantbot Technologies LP | 7.45K | $199.1K | — | Held |
| Walleye Trading LLC | 6.85K | $182.9K | — | Held |
| EXCHANGE TRADED CONCEPTS, LLC | 6.15K | $164.2K | — | Held |
| Neo Ivy Capital Management | 6.01K | $160.5K | — | Held |
| PNC Financial Services Group, Inc. | 5.24K | $139.9K | — | Held |
| Global Retirement Partners, LLC | 5.05K | $134.9K | — | Held |
| Kestra Advisory Services, LLC | 4.39K | $117.4K | — | Held |
| GAMMA Investing LLC | 3.41K | $91.1K | — | Held |
| GF FUND MANAGEMENT CO. LTD. | 3.32K | $88.8K | — | Held |
| HOLLENCREST CAPITAL MANAGEMENT | 3K | $80.1K | — | Held |
| Smartleaf Asset Management LLC | 2.6K | $69.3K | — | Held |
| SIMPLEX TRADING, LLC | 2.44K | $65K | — | Held |
| Nemes Rush Group LLC | 2K | $53.4K | — | Held |
| Leonteq Securities AG | 1.96K | $52.2K | $10.5K | Cut−$24.8K |
| Signature Equity Partners, LLC | 1.95K | $52.1K | — | Held |
| NISA INVESTMENT ADVISORS, LLC | 1.77K | $47.4K | — | Held |
| FEDERATED HERMES, INC. | 1.61K | $43.1K | — | Held |
| EverSource Wealth Advisors, LLC | 1.44K | $38.5K | — | Held |
| Steward Partners Investment Advisory, LLC | 1.43K | $38.1K | — | Held |
| Transamerica Financial Advisors, LLC | 1.33K | $35.7K | — | Held |
| IFP Advisors, Inc | 1.28K | $34.1K | $5.93K | Added$10.6K |
| JONES FINANCIAL COMPANIES LLLP | 1.28K | $34.1K | — | Held |
| Tower Research Capital LLC (TRC) | 1.14K | $30.5K | — | Held |
| Clearstead Advisors, LLC | 1.02K | $27.2K | — | Held |
| MEEDER ASSET MANAGEMENT INC | 984 | $26.3K | — | Held |
| Farther Finance Advisors, LLC | 958 | $25.6K | — | Held |
| Salomon & Ludwin, LLC | 917 | $24K | — | Held |
| Sterling Capital Management LLC | 890 | $23.8K | — | Held |
| Essential Partners LLC | 768 | $20.5K | $4.12K | Cut−$7.49K |